Results 11 to 20 of about 24,200 (214)

The road not taken: Less traveled roads from the TGN to the plasma membrane [PDF]

, 2015
: The trans-Golgi network functions in the distribution of cargo into different transport vesicles that are destined to endosomes, lysosomes and the plasma membrane. Over the years, it has become clear that more than one transport pathway promotes plasma
Anne Spang, Spang, Anne
core   +1 more source

Further Characterization of Dopamine Release by Permeabilized PC 12 Cells [PDF]

, 1987
Rat pheochromocytoma cells (PC 12) permeabilized with staphylococcal α-toxin release [3H]dopamine after addition of micromolar Ca2+. This does not require additional Mg2+-ATP (in contrast to bovine adrenal medullary chromaffin cells).
Ahnert-Hilger, G., Manfred Gratzl, Gratzl, Manfred, Gudrun Ahnert‐Hilger   +3 more
core   +1 more source

Novel role for proteinase-activated receptor 2 (PAR2) in membrane trafficking of proteinase-activated receptor 4 (PAR4) [PDF]

, 2012
Proteinase-activated receptors 4 (PAR(4)) is a class A G protein-coupled receptor (GPCR) recognized through the ability of serine proteases such as thrombin and trypsin to mediate receptor activation. Due to the irreversible nature of activation, a fresh
Robben, Joris, Cooke, Alexandra, Gould, Gwyn W., McIntosh, Kathryn A., Gould, Gwyn, Milligan, Graeme, Cunningham, Margaret Rose, Pediani, John D., Cooke, Alexandra E., McIntosh, Kathryn, Nilsson, Mary, Mundell, Stuart, Plevin, Robin, Cunningham, Margaret R., McIntosh, Kathryn A, Pediani, John D, Gould, Gwyn W, Pediani, John, Nilsson, Mary Francis, Cunningham, Margaret R, Cooke, Alexandra E   +20 more
core   +1 more source

Inhibition of activity of GABA transporter GAT1 by δ-opioid receptor [PDF]

, 2012
Analgesia is a well-documented effect of acupuncture. A critical role in pain sensation plays the nervous system, including the GABAergic system and opioid receptor (OR) activation.
Fucke, Thomas, Schwarz, Wolfgang, Xu, Nanjie, Pu, Lu, Pei, Gang, Gu, Quanbao, Xia, Peng, Ren, Shuanglai   +7 more
core   +1 more source

SLC6 transporter oligomerization [PDF]

, 2021
Transporters of the solute carrier 6 (SLC6) family mediate the reuptake of neurotransmitters such as dopamine, norepinephrine, serotonin, GABA, and glycine.
Jayaraman, Kumaresan; orcid:, Luethi, Dino; orcid:, Schütz, Gerhard J.; orcid:, Szöllősi, Dániel; orcid:, Reith, Maarten E. A.; orcid:, Das, Anand Kant, Sitte, Harald H.; orcid:, Stockner, Thomas; orcid:   +7 more
core   +3 more sources

Neurobeachin, a Regulator of Synaptic Protein Targeting, Is Associated with Body Fat Mass and Feeding Behavior in Mice and Body-Mass Index in Humans [PDF]

, 2012
Neurobeachin (Nbea) regulates neuronal membrane protein trafficking and is required for the development and functioning of central and neuromuscular synapses. In homozygous knockout (KO) mice, Nbea deficiency causes perinatal death.
Schiöth, H., Martin Klingenspor, Schiöth Helgi B., Fredriksson, Robert, Hölter, S.M., Josefin A. Jacobsson (177194), Klockars, A., Hrabě de Angelis Martin, Hrabě de Angelis, M., Sabine M Hölter, Rozman, Jane, Alsio, Johan, Kilimann, Manfred W., Siv Strömberg (177203), Martin Hrabě de Angelis, Wolfgang Wurst (712), Wurst, Wolfgang, de Angelis, M. H., Riserus, Ulf, Pawel K. Olszewski (177186), de Angelis, M., Kilimann, M., Klingenspor Martin, Alsiö Johan, Olszewski, P.K., Klopstock Thomas, Klopstock, T., Holter, Sabine, Rathkolb, B., Hölter, S. M., Jacobsson, Josefin A., Wurst, W., Alsiö, Johan,, Nicole Ehrhardt, Wolf Eckhard, Kilimann, M.W., Olszewski Pawel K., Kilimann Manfred W., Jan Rozman, Ralf Elvert, Ulf Risérus (177224), Hrabé de Angelis, Martin, Jacobsson, J. A., Wolf, E., Ehrhardt, Nicole, Elvert, Ralf, Becker, L., de Angelis, Martin Hrabě, Lore Becker (160172), Elvert, R., Wolfgang Hans (39864), Jacobsson Josefin A., Sabine M. Hölter (160170), Levine, Allen S., Klingenspor, Martin, Johan Alsiö, Risérus Ulf, Klockars, Anica,, Marcus, Claude, Jacobsson, Josefin A.,, Jacobsson, J.A., Claude Marcus, Anica Klockars (177212), Olszewski, P. K., Ehrhardt Nicole, Hölter, S., Hans, W., Schiöth, H. B., Birgit Rathkolb, Lore Becker, Ehrhardt, N., Valérie Gailus-Durner (125329), Klopstock, Thomas, Ulf Risérus, Fredriksson, R., Fuchs, Helmut, Ralf Elvert (177237), Gailus-Durner, Valerie, Wolfgang Wurst, Hölter Sabine M., Eckhard Wolf, Fuchs Helmut, Anica Klockars, Kilimann, Manfred W.,, Levine, A. S., Risérus, Ulf,, Thomas Klopstock, Levine, A.S., Helgi B Schiöth, Marcus Claude, Levine, A., Schiöth, H.B., Rathkolb, Birgit, Hans, Wolfgang, Robert Fredriksson (27811), Klockars, Anica, Manfred W Kilimann, Rozman, J., Rozman, Jan, Jan Rozman (149181), Olszewski, Pawel K.,, Hans Wolfgang, Helgi B. Schiöth (152210), Fuchs, H., Schiöth, Helgi B.,, Martin Hrabě de Angelis (2579524), Birgit Rathkolb (39867), Strömberg Siv, Manfred W. Kilimann (148306), Strömberg, Siv,, Valérie Gailus-Durner, Strömberg, S., Allen S Levine, Gailus-Durner, V., Helmut Fuchs, Claude Marcus (147851), Siv Strömberg, Eckhard Wolf (39870), Klockars Anica, Robert Fredriksson, Schiöth, Helgi B., Wurst Wolfgang, Kilimann, M. W., Elvert Ralf, Nicole Ehrhardt (177249), Fredriksson, Robert,, Josefin A Jacobsson, Alsiö, J., Olszewski, Pawel K., Johan Alsiö (177218), Jacobsson, J., Thomas Klopstock (160225), Martin Klingenspor (68144), Levine Allen S., Becker, Lore, Stromberg, Siv, Wolfgang Hans, Marcus, C., Helmut Fuchs (39863), Klingenspor, M., Fredriksson Robert, Rathkolb Birgit, Olszewski, P., Hoelter, Sabine M., Pawel K Olszewski, Allen S. Levine (177271), Gailus-Durner Valérie, Wolf, Eckhard, Becker Lore, Rozman Jan, Riserus, U.   +150 more
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Stable Dopamine-Signaling mRNA Co-Expression in the Substantia Nigra Is Deregulated in Pathological Conditions, but Not in Dopamine Transporter Knockout Rats

Biomolecules
Dopamine transporter (DAT) mutations are associated with neurological and psychiatric diseases, and DAT gene knockout in rats (DAT-KO) provides an opportunity to evaluate the DAT role in pathological conditions.
Anastasia N. Vaganova, Zoia S. Fesenko, Anna B. Volnova, Raul R. Gainetdinov   +3 more
doaj   +1 more source

Prediction of 123I-FP-CIT SPECT Results from First Acquired Projections Using Artificial Intelligence

Diagnostics
Background/Objectives: 123I-FP-CIT dopamine transporter imaging is commonly used for the diagnosis of Parkinsonian syndromes in patients whose clinical presentation is atypical. Prolonged immobility, which can be difficult to maintain in this population,
Wadi’ Othmani, Arthur Coste, Dimitri Papathanassiou, David Morland   +3 more
doaj   +1 more source

Kelvin Probe Force Microscopy in Bionanotechnology: Current Advances and Future Perspectives

Advanced Materials, EarlyView.
Kelvin probe force microscopy (KPFM) enables the nanoscale mapping of electrostatic surface potentials. While widely applied in materials science, its use in biological systems remains emerging. This review presents recent advances in KPFM applied to biological samples and provides a critical perspective on current limitations and future directions for
Ehsan Rahimi, Mario Palacios‐Corella, Arjan Mol, Salvador Pané, Josep Puigmartí‐Luis   +4 more
wiley   +1 more source

AI–Guided 4D Printing of Carnivorous Plants–Inspired Microneedles for Accelerated Wound Healing

Advanced Materials, EarlyView.
This work presents an artificial intelligence (AI)‐guided 4D‐printed microneedle platform inspired by carnivorous plants for wound healing. A thermo‐responsive shape memory polymer enables body temperature–triggered self‐coiling for autonomous wound closure.
Hyun Lee, Moon‐Jo Kim, DongEung Kim, Chan Ho Moon, Seojoon Bang, Hyeong Seok Kang, Ju Yeong Gwon, Jong Hwa Seo, Junhyub Jeon, Junhyuk Son, Munwon Lim, Minho Kang, Dong Yun Lee, Donghyun Lim, Jung‐Hoon Park, Gi Doo Cha, Soo‐Hong Lee, Tae‐Sik Jang, Kisuk Yang, Yunho Jeong, Youngho Eom, Hyun‐Do Jung   +21 more
wiley   +1 more source