Results 221 to 230 of about 2,920,752 (311)

Targeting Microbiome Metabolites: Reshaping Immunotherapy and Clinical Management Strategies for Colorectal Cancer

iMetaMed, EarlyView.
The occurrence and progression of colorectal cancer are intricately linked to metabolites produced by the gut microbiota. Metabolites generated by pathogenic microbial communities can promote colorectal cancer development by reshaping the immune microenvironment.
Xinrui Yang, Ke Zhang, Lijie Xia, Jinyao Li   +3 more
wiley   +1 more source

Seasonal variation in D2/3 dopamine receptor availability in the human brain. [PDF]

Eur J Nucl Med Mol Imaging
Sun L, Malén T, Tuisku J, Kaasinen V, Hietala JA, Rinne J, Nuutila P, Nummenmaa L.   +7 more
europepmc   +1 more source

Metabolomic and lipidomic signatures of Helicobacter pylori infection: Unveiling biochemical pathways associated with neurodegeneration

iMetaOmics, EarlyView.
Our study employed an integrated lipidomics and metabolomics approach to elucidate Helicobacter pylori‐driven metabolic perturbations along the gut–brain axis. H. pylori infection was established in gastric epithelial (AGS) cells, and the resulting conditioned media (secretome) was collected and exposed to neuronal (IMR‐32) cells.
Meenakshi Kandpal, Tarun Prakash Verma, Siddharth Singh, Hamendra Parmar, Hem Chandra Jha   +4 more
wiley   +1 more source

Tyrosine Hydroxylase Inhibitors and Dopamine Receptor Agonists Combination Therapy for Parkinson's Disease. [PDF]

Int J Mol Sci
Yi LX, Tan EK, Zhou ZD.
europepmc   +1 more source

Organic neuromorphic electronics powering intelligent sensory and edge computing systems

InfoMat, EarlyView.
Organic electronic materials are promising candidates for neuromorphic sensing applications, including chemical, physical, visual, and multimodal sensing, owing to their mechanical softness, biocompatibility, and intrinsic ionic–electronic coupling.
Seungjun Woo, Minji Chung, Hyun Woo Song, Seoyoung Kim, Eun Kwang Lee, Joon Hak Oh   +5 more
wiley   +1 more source

PET clinical study of novel antipsychotic LB-102 demonstrates unexpectedly prolonged dopamine receptor target engagement. [PDF]

Neuropsychopharmacology
Wong DF, Chand GB, Caito N, Eramo A, Grattan VT, Hixon MS, Nicol G, Lessie E, Prensky Z, Kuwabara H, Tian L, Valenta I, Schindler TH, Gründer G, Vaino AR.   +14 more
europepmc   +1 more source

Sex differences in sensitivity to dopamine receptor manipulations of risk-based decision making in rats. [PDF]

Neuropsychopharmacology
Wheeler AR, Truckenbrod LM, Boehnke A, Kahanek P, Orsini CA.   +4 more
europepmc   +1 more source

Disease-Associated Dopamine Receptor D2 Variants Exhibit Functional Consequences Depending on Different Heterotrimeric G-Protein Subunit Combinations. [PDF]

Biomedicines
Niebrügge N, Trovato O, Praschberger R, Lieb A.   +3 more
europepmc   +1 more source

Suppression of dopamine receptor 2 inhibits the formation of human prostate cancer PC‑3‑derived cancer stem cell‑like cells through AMPK inhibition. [PDF]

Oncol Lett
Park J, Jang HJ, Jung WK, Kang DY, Gong YL, Kim HJ, Kang JS, Yang JW, Byun Y, Park SK.   +9 more
europepmc   +1 more source

A subset of dopamine receptor-expressing neurons in the nucleus accumbens controls feeding and energy homeostasis. [PDF]

Nat Metab
Liu Y, Wang Y, Zhao ZD, Xie G, Zhang C, Chen R, Zhang Y.   +6 more
europepmc   +1 more source