Results 291 to 300 of about 835,318 (379)

Item Response Modeling and Artificial Neural Network for Differentiation of Parkinson's Patients and Subjects Without Evidence of Dopaminergic Deficit

CPT: Pharmacometrics &Systems Pharmacology, EarlyView.
ABSTRACT Approximately 15% of patients suspected of having Parkinson's disease (PD) present dopamine active transporter (DaT) scans without evidence of dopaminergic deficits (SWEDD), most of which will never develop PD. Leveraging Movement Disorders Society Unified Parkinson's Disease Rating Scale (MDS‐UPDRS) scores from the Parkinson's Progression ...
Leticia Arrington, Sven C. van Dijkman, Elodie L. Plan, Mats O. Karlsson   +3 more
wiley   +1 more source

Synaptic vesicle characterization of iPSC-derived dopaminergic neurons provides insight into distinct secretory vesicle pools. [PDF]

NPJ Parkinsons Dis
Fujise K, Mishra J, Rosenfeld MS, Rafiq NM.   +3 more
europepmc   +1 more source

Neuroprotective Effects of Ascorbic Acid, Vanillic Acid, and Ferulic Acid in Dopaminergic Neurons of Zebrafish. [PDF]

Biomedicines
Hedayatikatouli F, Kalyn M, Elsaid D, Mbesha HA, Ekker M.   +4 more
europepmc   +1 more source

Semaglutide to remodel mitochondrial dynamics and mitophagy balance for vascular dementia therapy

VIEW, EarlyView.
The effects of semaglutide on IR, mitochondrial dynamics, and mitophagy in the hippocampus of BCAS mice after CCH. It was shown that semaglutide maintained the balance of mitochondrial dynamics and mitophagy by improving IR and passing through GLP‐1R/PI3K/Akt pathway, reduced hippocampal neuroinflammation and neuron loss, and thus promoted the recovery
Xiaoyan Yang, Peng Feng, Hongxu Zhu, Mingkang Wang, Nan Li, Bo Bai, Yuxiang Sun, Zhongrui Yan, Wenshi Wei, Jie Chang, Christian Hölscher, Wenxian Du   +11 more
wiley   +1 more source

Yin Yang 1 and guanine quadruplexes protect dopaminergic neurons from cellular stress via transmissive dormancy. [PDF]

Nat Commun
Zuurbier KR, Fonseca RS, Arneaud SLB, Wall JM, Kim J, Tatge L, Otuzoglu G, Bali S, Metang P, Douglas PM.   +9 more
europepmc   +1 more source

Treatment of Neurogenic Voice Disorders

World Journal of Otorhinolaryngology - Head and Neck Surgery, EarlyView.
ABSTRACT This overview serves as a foundational resource for clinicians caring for neurologically complex patients presenting with voice complaints. Neurogenic voice disorders are diverse in their clinical presentations and therapeutic approaches. A thorough medical history, including family history, detailed laryngeal examination, voice assessments ...
Mausumi Syamal
wiley   +1 more source

Spasmodic Dysphonia

World Journal of Otorhinolaryngology - Head and Neck Surgery, EarlyView.
ABSTRACT Spasmodic dysphonia is a laryngeal dystonia that can present as adductor, abductor, or mixed types, with or without tremor. The etiology is not understood fully. Comprehensive evaluation is required to establish the diagnosis. Treatments include voice therapy, medications, botulinum toxin injection, laryngeal surgery, deep brain stimulation ...
Aaron J. Jaworek, Robert T. Sataloff
wiley   +1 more source

Fibrin-Polycaprolactone Scaffolds for the Differentiation of Human Neural Progenitor Cells into Dopaminergic Neurons. [PDF]

ACS Omega
Ramirez SP, Hernandez I, Dorado ZN, Loyola CD, Roberson DA, Joddar B.   +5 more
europepmc   +1 more source

Applications of Artificial Intelligence in Neurological Voice Disorders

World Journal of Otorhinolaryngology - Head and Neck Surgery, EarlyView.
ABSTRACT Neurological voice disorders, such as Parkinson's disease, laryngeal dystonia, and stroke‐induced dysarthria, significantly impact speech production and communication. Traditional diagnostic methods rely on subjective assessment, whereas artificial intelligence (AI) offers objective, noninvasive, and scalable solutions for voice analysis. This
Dongren Yao, Aki Koivu, Kristina Simonyan   +2 more
wiley   +1 more source

Functional maturation and experience-dependent plasticity in adult-born olfactory bulb dopaminergic neurons

Tufo C, Cheah M, Lipovsek M, Browne LP, Grubb MS.   +4 more
europepmc   +1 more source