Results 101 to 110 of about 9,627,086 (290)

A Novel Pak1 Activator Ameliorates ER Stress for HFpEF Therapy

Advanced Science, EarlyView.
Chronic metabolic stress is a major contributor to HFpEF progression. Under prolonged metabolic stress, Pak1 activity becomes impaired, contributing to disrupted ER proteostasis, cardiomyocyte apoptosis, fibrosis, and diastolic dysfunction. Mechanistically, Pak1 overexpression activates the ERK1/2–MNK1–eIF4E signaling axis, promotes translational ...
Honglin Xu, Hongyuan Zhang, Tayyiba Azam, Susanne S. Hille, Yingjuan Liu, Min Zi, Jiaqing Lang, He Yu, Yujia Cao, Bernard D. Keavney, Tamer M. A. Mohamed, Jessica M. Miller, Riham R. E. Abouleisa, Ming Xu, Elizabeth J. Cartwright, Oliver J. Müller, Ming Lei, Xin Wang   +17 more
wiley   +1 more source

IDENTIFICATION OF AIR RADAR TARGETS USING THE DOPPLER EFFECT FROM A HEATED JET ENGINE

Вестник Дагестанского государственного технического университета: Технические науки, 2018
Objectives The aim of the study is to develop a methodology for identifyingaircraft by the deflections of an electromagnetic radar beam by a heated jet engine. Methods Atoms of the crystal lattice of the metallic parts of the operating jet engine will be
P. Sh. Adalaeva, T. G. Aigumov, S. V. Magomedova, T. A. Chelushkina   +3 more
doaj   +1 more source

Acoustic topological beam nonreciprocity via the rotational Doppler effect. [PDF]

Sci Adv, 2022
Wang Q, Zhou Z, Liu D, Ding H, Gu M, Li Y.   +5 more
europepmc   +1 more source

Sonoselective Transfection of Glioma Endothelium

Advanced Science, EarlyView.
Delivering non‐viral, gene‐bearing nanoparticles with thiol‐decorated surfaces to gliomas with focused ultrasound yields transfection tropism for endothelial cells. From this platform, “sonoselective” transfection of glioma endothelium is achieved via incorporation of an endothelial cell‐specific promoter.
Anna C. Debski, Catherine M. Gorick, Victoria R. Breza, Jackson Tirrell, Krishan Perumal, Katherine M. Nowak, Ji Song, Natasha D. Sheybani, Richard J. Price   +8 more
wiley   +1 more source

Remote Measurement of the Angular Velocity Vector Based on Vectorial Doppler Effect Using Air-Core Optical Fiber. [PDF]

Research (Wash D C), 2022
Wan Z, Liang Y, Zhang X, Tang Z, Fang L, Ma Z, Ramachandran S, Wang J.   +7 more
europepmc   +1 more source

Engineered Brain‐Targeted Exosomes Delivering FGF1 for Sustained Glycemic Regulation and Multitarget Neurovascular Protection in Diabetic Stroke

Advanced Science, EarlyView.
ABSTRACT Diabetic stroke is characterized by a hyperglycemic and pro‐inflammatory microenvironment that exacerbates neurovascular dysfunction. However, the blood–brain barrier (BBB) remains a formidable obstacle, restricting the delivery of most therapeutic molecules.
Bixin Shen, Chengxiang Zhang, Junhui Wang, Xichong Zhong, Shihao Chen, Xue Wang, Xiaokun Li, Li Lin   +7 more
wiley   +1 more source

The task of detecting inconspicuous flying objects based on recording changes in the radiation characteristics of the Starlink satellite network

Вестник Самарского государственного технического университета. Серия: Технические науки
This work is devoted to the detection of inconspicuous flying objects (unmanned aerial vehicles) by ground-based means. The analysis of traditional methods of solving the problem under consideration, based on the use of active radar, is carried out.
Vladimir N. Vorozheikin, Dmitry A. Polyakov   +1 more
doaj   +1 more source

Analysis of Multi-Path Fading and the Doppler Effect for Reconfigurable-Intelligent-Surface-Assisted Wireless Networks. [PDF]

Entropy (Basel), 2022
Wu G.
europepmc   +1 more source

m6A‐Driven Pexophagy Triggers Placental Ferroptosis to Impair Fetal Growth Upon Environmental Stress

Advanced Science, EarlyView.
Prenatal environmental stress exposure promotes m6A modification to drive PEX2‐dependent pexophagy, thereby causing placental ferroptosis and FGR. ABSTRACT The role and underlying mechanisms of placental ferroptosis in fetal growth restriction (FGR) induced by environmental stress remain poorly understood.
Xin‐Xin Zhang, Ye‐Xin Luo, Cheng‐Fang Sun, Rui Pan, Yu‐Xi Wu, Zhi Yuan, Xin‐Run Wang, Xu‐Dong Zhang, Lan‐Lan Wu, Xiang‐Yu Yao, Zhan‐Dong Song, Wei Chang, Tian Wei, Pan‐Yuan Cai, Tian‐Ci Zhang, Yong‐Wei Xiong, De‐Xiang Xu, Hua Wang, Hua‐Long Zhu   +18 more
wiley   +1 more source

Experimental study on human weak echo characteristics of UWB radar in complex occlusion scenes

Meitan kexue jishu
Ultra-wideband (UWB) radar is widely used in the field of penetration detection. In the disaster scenarios such as mine collapse and building collapse caused by natural or human factors, the propagation medium is non-uniform and discontinuous, and it is ...
Hu WEN, Feiyang JIN, Yuqi WANG, Bocong LIU, Shixing FAN, Yuan HUANG, Xuezhao ZHENG, Duo ZHANG, Wei WU   +8 more
doaj   +1 more source