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Refining a preclinical model of viral myocarditis in accordance with biotech standards

Animal Models and Experimental Medicine, EarlyView.
This study aimed to refine a murine model of Coxsackievirus B3‐induced myocarditis by integrating dietary and imaging innovations to improve animal welfare, data quality, and clinical applicability. The refined diet significantly reduced animal health burden, reduced weight loss, and stabilized blood glucose during development of cardiac inflammation ...
Jonas Stewen +9 more
wiley +1 more source

Silk Fibroin for Cardiovascular Medical Devices: Review of Material Properties, Applications, and Clinical Potential

Advanced NanoBiomed Research, EarlyView.
Silk fibroin is an attractive natural biomaterial that can be engineered into diverse cardiovascular constructs, including vascular grafts, cardiac patches, heart valves, and stent coatings. Its tunable biological and mechanical properties have driven substantial preclinical progress; however, widespread clinical translation in cardiovascular ...
Mahsa Haghighattalab +8 more
wiley +1 more source

Reversed Doppler effect based on hybridized acoustic Mie resonances. [PDF]

Sci Rep, 2020
Liu C, Long H, Zhou C, Cheng Y, Liu X.
europepmc +1 more source

The Doppler Effect in Resonance Lines [PDF]

Proceedings of the National Academy of Sciences, 1940
openaire +3 more sources

Self‐Assembled Telecom Color Centers in Silicon and Their Growth Environment

Advanced Physics Research, EarlyView.
Influence of the growth pressure during the formation of self‐assembled color centers in silicon grown by molecular beam epitaxy at ultra‐low temperatures on the color center's photoluminescence spectral signature. The growth pressure crucially determines color center selectivity, as evidenced by G‐centers, W‐centers, and T‐centers, matrix purity, and ...
Jacqueline Marböck +9 more
wiley +1 more source

Modelling, Analysis, and Simulation of the Micro-Doppler Effect in Wideband Indoor Channels with Confirmation Through Pendulum Experiments. [PDF]

Sensors (Basel), 2020
Abdelgawwad A, Borhani A, Pätzold M.
europepmc +1 more source

Computational fluid dynamics simulations of airflow through the nasal passages of rhinolophoid bats

The Anatomical Record, EarlyView.
Abstract The nasal passages of bats that emit their echolocation call through their nostrils have adapted for sound emission as well as standard respiratory and olfactory functions. Rhinolophids, hipposiderids and rhinonycterids all use a high duty cycle (HDC) echolocation strategy.
Carley Goodwin +7 more
wiley +1 more source

Tracheal chambers as a key innovation for high‐frequency emission in bat echolocation

The Anatomical Record, EarlyView.
Abstract Key innovations are pivotal for biodiversity and facilitating evolutionary success, enabling organisms' adaptation to various ecological niches through the diversification of phenotypic traits. In mammals, notable adaptations include evolving hypsodonty for grazing on grasses and, for bats, evolving echolocation and wing acquisition.
Nicolas L. M. Brualla +7 more
wiley +1 more source

Higher Complement C4 Gene Copy Number Constitutes a Shared Genetic Risk Factor for Giant Cell Arteritis and IgA Vasculitis

Arthritis &Rheumatology, EarlyView.
Objective Low copy number (CN) of complement C4 isoforms and high CN of retroviral HERV‐K elements are known risk factors for many immune‐mediated inflammatory diseases (IMIDs), often showing sex‐biased effects. Here, we assessed whether CN variation within the C4 gene contributes to giant cell arteritis (GCA) and IgA vasculitis (IgAV), two complex ...
Laura Martínez‐Gutiérrez +295 more
wiley +1 more source

Integrated Clinical and Proteomic Profiling of CD19 Chimeric Antigen Receptor T Cell Therapy in Progressive Systemic Sclerosis

Arthritis &Rheumatology, EarlyView.
Objective To characterize the clinical, immunologic, and proteomic changes associated with CD19 chimeric antigen receptor T cell therapy in patients with progressive systemic sclerosis (SSc). Methods Patients with progressive SSc received CD19 chimeric antigen receptor (CAR)‐T cell therapy and were observed longitudinally for safety, clinical efficacy,
Chenhan Jia +16 more
wiley +1 more source

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