Results 81 to 90 of about 105,814 (313)

Gut Metabolite Indole‐3‐Propionic Acid Regulates Macrophage Autophagy Through PPT1 Inhibiting Aging‐Related Myocardial Fibrosis

Advanced Science, EarlyView.
IPA is an intestinal tryptophan metabolite whose effects decline with decreased heart function. Supplementing IPA can alleviate the aging‐related myocardial fibrosis through PPT1. PPT1 is a key protein localized to lysosomes, and IPA can restore macrophage autophagy function by regulating PPT1 expresssions, thereby reducing aging‐related myocardial ...
Jing Lu, Hongyan Wang, Haiyu Zhang, Jiahao Li, Hanqi Li, Qiuyu Chen, Dongyu Han, Jialiang Liu, Lin Lv, Jie Xiong, Keying Yuan, Xianpeng Wei, Siqi Sheng, Fukai Liu, Yuanqi Shi, Zengxiang Dong, Yue Li   +16 more
wiley   +1 more source

Accelerated Algorithm based on Modified Z-Buffer for Numerically Simulating the Dynamic Radar Echo from Wind Turbines [PDF]

Journal of Electromagnetic Engineering and Science
As wind farms increase in scale, the computation speed of traditional methods struggles to meet the requirements for simulating the dynamic radar echo they produce.
Bo Tang, Zhendong Zhu, Zhiyu Shang, Bin Xu, Gang Liu, Cheng Fan   +5 more
doaj   +1 more source

Spatiotemporal Acoustic Communication by a Single Sensor via Rotational Doppler Effect. [PDF]

Adv Sci (Weinh), 2023
Zhang C, Jiang X, He J, Li Y, Ta D.
europepmc   +1 more source

The GRK2/AP‐1 Signaling Axis Mediates Vascular Endothelial Dysfunction and Atherosclerosis Induced by Oscillatory Low Shear Stress

Advanced Science, EarlyView.
This study highlights GRK2 is a central mediator in OSS‐induced endothelial dysfunction. OSS activates GPCRs in endothelial cells, leading to GRK2 phosphorylation and the activation of AP‐1. AP‐1 induces inflammation, while also promoting NR4A1 expression and anchoring LKB1 in the nucleus, which suppresses AMPK activity. This cascade causes endothelial
Li‐Da Wu, Yi Shi, Chao‐Hua Kong, Ai‐Qun Chen, Ying Kang, Jun‐Yan Kan, Xiao‐Min Jiang, Peng Chu, Dong‐Chen Wang, Yi‐Fei Lv, Zhi‐Yuan Qian, Zi‐Hao Jiang, Yun‐Wei Chen, Yue Sun, Rui‐Rui Chang, Wen‐Ying Zhou, Yue Gu, Jun‐Xia Zhang, Shao‐Liang Chen   +18 more
wiley   +1 more source

Study of frequency band in Von Karman excitation of Francis turbine

Journal of Fluid Science and Technology
The objective of this study is to reveal the frequency characteristics caused by Von Karman excitation observed at the stationary field of a Francis turbine.
Takero MUKAI, Masahiko NAKAZONO, Kotaro TEZUKA   +2 more
doaj   +1 more source

Rotating axis measurement based on rotational Doppler effect of spliced superposed optical vortex. [PDF]

Nanophotonics, 2023
Zhu X, Qiu S, Liu T, Ding Y, Tang R, Liu Z, Chen X, Ren Y.   +7 more
europepmc   +1 more source

A Full‐Range Proximity‐Tactile Sensor Based on Multimodal Perception Fusion for Minimally Invasive Surgical Robots

Advanced Science, EarlyView.
A full‐range proximity‐tactile sensing module is developed for safe operation of surgical robots, which performs multimodal fusion perception through ultrasonic sensor for long‐range proximity detection, capacitive sensor for close‐range proximity sensing, and triboelectric sensor for tactile sensing.
Dongsheng Li, Tianci Ji, Yuyang Sun, Zhongbin Zhang, Aomen Li, Mengjiao Qu, Dongze Lv, Jin Xie, Huicong Liu   +8 more
wiley   +1 more source

Evaluation of Doppler Effect Error Affecting the Radio Altimeter Altitude Measurements. [PDF]

Sensors (Basel), 2022
Češkovič M, Kurdel P, Gecejová N, Labun J, Laššák M.   +4 more
europepmc   +1 more source

The Multitarget Compound ZLY032 Achieves Treatment of Chronic Wounds

Advanced Science, EarlyView.
ZLY032, a dual free fatty acid receptor 1/peroxisome proliferator‐activated receptor δ agonist, accelerates wound healing in normal/diabetic/methicillin‐resistant Staphylococcus aureus‐infected models by promoting angiogenesis, reducing inflammation, and exhibiting antibacterial activity via argininosuccinate lyase targeting, with demonstrated efficacy
Manyu Gong, Zhiyuan Du, Tiantian Gong, Yu Wang, Chenchen Yin, Bosi Sun, Zijia Liu, Lianru Chen, Zibin Liao, Wenxin Wang, Tianjiao Zhao, Yifei Wang, Ying Dong, Kexin Wang, Mengru Ma, Weijun Li, Jiacheng Li, Haodong Li, Congcong Lin, Ying Zhang, Yu Liu, Xin Liu, Tao Ban, Hongxia Bao, Ying Zhang, Yang Zhang, Zheng Li, Lei Jiao   +27 more
wiley   +1 more source

Acoustic topological beam nonreciprocity via the rotational Doppler effect. [PDF]

Sci Adv, 2022
Wang Q, Zhou Z, Liu D, Ding H, Gu M, Li Y.   +5 more
europepmc   +1 more source