Results 31 to 40 of about 17,042 (262)

Poly(lactic‐co‐glycolic acid) Nanoparticles for IL‐12 Self‐Amplifying RNA Delivery in Glioblastoma Models

Advanced Functional Materials, EarlyView.
xxxx. ABSTRACT Glioblastoma (GBM) remains one of the most lethal brain cancers, with median survival rarely exceeding 15 months after diagnosis. Interleukin‐12 (IL‐12) is a potent immunostimulatory cytokine capable of reshaping the tumor microenvironment (TME), yet its clinical translation is hindered by systemic toxicity and short half‐life. RNA‐based
Fatima Hameedat, Johan Sebastian Lopez‐Parra, Willem M. H. Hoogaars, Emma Dijkstra, Cynthia Huang, Irafasha C. Casmil, Anna K. Blakney, Peter Olinga, Barbara Rothen‐Rutishauser, Hélder A. Santos, Alke Petri‐Fink, Flávia Sousa   +11 more
wiley   +1 more source

An automated multi-point primary vibration calibration system

Measurement: Sensors, 2021
In this study, we developed an automated, multi-point primary vibration calibration system using a two-axis positioning stage and a laser Doppler vibrometer. The proposed system offers low-cost, convenient, and automated multi-point vibration calibration,
Wataru Kokuyama, Tomofumi Shimoda, Hideaki Nozato   +2 more
doaj   +1 more source

From Clinic to Computation: Multiscale Bioengineering Strategies for Durable Biological Aortic Valve Replacements

Advanced Functional Materials, EarlyView.
Bioprosthetic aortic valves have revolutionized the treatment of aortic stenosis, but their durability is limited by structural valve deterioration (SVD). This review focuses on the pericardial tissue at the heart of these valves, examining how its mechanical properties and calcification drive fatigue and failure.
Gabriele Greco, Pierfrancesco Gaziano, Serena Anglese, Simone Morganti, Carlo de Vincentiis, Ferdinando Auricchio, Michele Marino, Michele Conti   +7 more
wiley   +1 more source

Leveraging Multi-LEO Satellite Signals for Opportunistic Positioning

IEEE Access
The study of navigation solutions other than GNSS is becoming increasingly important due to growing concerns about the vulnerability of GNSS to interference. The use of existing LEO satellite signals is a promising option in this respect.
Nabil Jardak, Ronan Adam, Quentin Jault
doaj   +1 more source

Opportunistic In-Flight INS Alignment Using LEO Satellites and a Rotatory IMU Platform

Aerospace, 2021
With the emergence of numerous low Earth orbit (LEO) satellite constellations such as Iridium-Next, Globalstar, Orbcomm, Starlink, and OneWeb, the idea of considering their downlink signals as a source of pseudorange and pseudorange rate measurements has
Farzan Farhangian, Hamza Benzerrouk, Rene Landry   +2 more
doaj   +1 more source

Symposium on satellite Doppler positioning

Eos, Transactions American Geophysical Union, 1979
The Second International Geodetic Symposium on Satellite Doppler Positioning was held in Austin, Texas, from January 22 to January 26,1979. The symposium was sponsored by the Defense Mapping Agency and the National Ocean Survey, hosted by the Applied Research Laboratories of the University of Texas at Austin, and sanctioned by the International ...
openaire   +1 more source

Computational Modeling Meets 3D Bioprinting: Emerging Synergies in Cardiovascular Disease Modeling

Advanced Healthcare Materials, EarlyView.
Emerging advances in three‐dimensional bioprinting and computational modeling are reshaping cardiovascular (CV) research by enabling more realistic, patient‐specific tissue platforms. This review surveys cutting‐edge approaches that merge biomimetic CV constructs with computational simulations to overcome the limitations of traditional models, improve ...
Tanmay Mukherjee, Mehdi Salar Amoli, Sarah Rezapourdamanab, Lama Rita El Shammas, Martin L. Tomov, Emilio A. Mendiola, Vahid Serpooshan, Reza Avazmohammadi   +7 more
wiley   +1 more source

Joint pseudo-range and Doppler positioning method with LEO Satellites‘ signals of opportunity

Satellite Navigation
Low Earth Orbit (LEO) satellites, with their wide coverage and large number, have gradually become a crucial platform and means for navigation and positioning services. Compared to other LEO constellations, Starlink has over 6000 satellites in orbit, and
Ying Xu, Yue Liu, Ming Lei, Ming Gao, Zhibo Fang, Cheng Jiang   +5 more
doaj   +1 more source

Simvastatin Restores Uteroplacental Hemodynamics and Trophoblast Function in Obstetric Antiphospholipid Syndrome in a Placenta‐on‐a‐Chip Model

Advanced Healthcare Materials, EarlyView.
Simvastatin mitigates placental hypoperfusion in OAPS by ameliorating abnormal uteromaternal hemodynamics and enhancing trophoblast invasion via optimized endothelial cell interactions under pathological shear stress, as evidenced by results from a placenta‐on‐a‐chip platform.
Hongli Liu, Yuan Wang, Yanjun Cai, Ruixin Guo, Shunhua Liu, Tingting Chen, Tingting Sun, Ruiheng Huo, Tengwei Liu, Qingfeng Lv, Xietong Wang   +10 more
wiley   +1 more source

Doppler Positioning with LEO Mega-Constellation: Equation Properties and Improved Algorithm

Remote Sensing
Doppler positioning, as an early form of positioning, has regained significant research interest in the context of Low Earth Orbit (LEO) satellites.Given the LEO mega-constellation scenario, the objective function of Doppler positioning manifests ...
Zichen Xu, Zongnan Li, Xiaohui Liu, Zhimin Ji, Qianqian Wu, Hao Liu, Chao Wen   +6 more
doaj   +1 more source