Results 121 to 130 of about 16,506,777 (367)
Molecular Oncology, EarlyView.This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns +10 more
wiley +1 more source
Stock Prices, Exchange Rates and Monetary Policy [PDF]
This paper attempts to model the relationship between monetary policy and financial asset prices. We develop an aggregative model under forward-looking rational expectations to analyse the optimal monetary policy response to stock prices and exchange ...
Dor, Eric, Durré, Alain
core
Incidência de mutação no códon 12 do protoncogene K-ras em carcinoma de próstata humana em uma amostra da população brasileira [PDF]
, 2004 José Raul Cisternas Gajardo +4 more
openalex +1 more source
Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma
Molecular Oncology, EarlyView.The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic +5 more
wiley +1 more source
Molecular Oncology, EarlyView.Targeted therapy was evaluated in SHH medulloblastoma using neuroepithelial stem cell (NES) and tumor‐derived NES‐like (tNES) models in 2D monolayers and 3D spheroids. PI3K, AKT, and CDK4/6 inhibitors had minimal effects in NES but markedly reduced viability and growth and induced apoptosis in tNES cells, revealing distinct therapeutic vulnerabilities.
Monika Lukoseviciute +4 more
wiley +1 more source
Hyperbaric Oxygen Does Not Prevent Neurologic Sequelae after Carbon Monoxide Poisoning [PDF]
, 2002 Benjamin Gilmer +3 more
openalex +1 more source
, 2013 Neste estudo analisou-se o efeito do Treinamento e uso de Ficha de Avaliacao Sistematizada para controle da dor apos cirurgia cardiaca, sobre a intensidade da dor e o consumo de morfina suplementar.
Magda Aparecida Santos Silva +2 more
semanticscholar +1 more source
Molecular Oncology, EarlyView.Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova +14 more
wiley +1 more source
Rate response and cardiac resynchronisation therapy in chronic heart failure: higher cardiac output does not acutely improve exercise performance: a pilot trial [PDF]
, 2008 Griet Thielen +4 more
openalex +1 more source
Incapacidade relacionada à dor lombar crônica: prevalência e fatores associados
, 2012 A incapacidade relacionada a dor lombar cronica (DLC) e um fenomeno complexo e multifatorial. O objetivo desse estudo foi identificar a prevalencia e os fatores associados a incapacidade em pacientes com dor lombar cronica. Estudo transversal com amostra
M. D. G. Salvetti +3 more
semanticscholar +1 more source