Results 101 to 110 of about 110,611 (310)

Liquid biopsy‐based diagnostic evaluation of hypermethylated CpG sites for ovarian cancer diagnosis

open access: yesMolecular Oncology, EarlyView.
This schematic outlines the workflow from biomarker identification to duplex MethyLight assay validation for epithelial ovarian cancer diagnosis using cfDNA‐based liquid biopsy. Initial screening of hypermethylated CpG candidates (cg02957270, cg10061138 cg00480298, COL2A1) was performed in tissue using ARMS‐PCR, COBRA, qPCR and image analysis. Selected
Deepa Bisht   +3 more
wiley   +1 more source

Dor muscular tardia e os niveis de creatina quinase : revisão

open access: yes, 2000
Essa revisão busca analisar estudos sobre o fenômeno da dor musculares tardios relacionados com os níveis de Creatina quinase do plasma, apresentando trabalhos sobre o fenômeno da dor muscular tardia, sobre o papel da creatina quinase no metabolismo, e ...
Ricardo Andre Beranger Almeida
core  

Análise dos mecanismos neurofisiológicos envolvidos no efeito da terapia manual (mobilização articular) na dor aguda e crônica [PDF]

open access: yes, 2013
Tese (doutorado) - Universidade Federal de Santa Catarina, Centro de Ciências Biológicas, Programa de Pós-Graduação em Neurociências, Florianópolis, 2013Evidências sugerem que as técnicas de terapia manual são efetivas no tratamento de problemas músculo ...
Martins, Daniel Fernandes
core  

Falls in chronic pain elderly patients: prevalence and associated factors

open access: yes, 2011
JUSTIFICATIVA E OBJETIVOS: A prevalência de queda e dor crônica é elevada em idosos com importantes consequências para a qualidade de vida. Verificar associação entre estes dois agravos pode ajudar a prevenir incapacidades e sofrimentos. O objetivo deste
DELLAROZZA, Mara Solange Gomes   +5 more
core   +1 more source

Mycobacterial cell division arrest and smooth‐to‐rough envelope transition using CRISPRi‐mediated genetic repression systems

open access: yesFEBS Open Bio, EarlyView.
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point   +7 more
wiley   +1 more source

Ultrasound-guided peripheral nerve blocks in anticoagulated patients – case series

open access: yesBrazilian Journal of Anesthesiology, 2017
Background and objectives: The advent of ultrasound has brought many benefits to peripheral nerve blocks. It includes both safety and effectiveness, given the possibility of visualizing the neurovascular structures and the needle during the procedure ...
Luis Eduardo Silveira Martins   +4 more
doaj   +1 more source

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

open access: yesFEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei   +3 more
wiley   +1 more source

Vitamin D and chronic pain in the elderly

open access: yes, 2013
BACKGROUND AND OBJECTIVES: Chronic pain is a frequent complaint during medical visits, especially among the elderly. In the attempt to find more effective therapies with less adverse effects in this population, especially considering elderly people with ...
Moraes, Niele [UNIFESP]   +2 more
core   +1 more source

Ultrasound-guided selective nerve blocks for trigger finger surgeries to maintain flexion/extension of fingers – Case series

open access: yesBrazilian Journal of Anesthesiology, 2019
Background: A patient's ability to move his/her fingers during hand surgery may be helpful to surgeons because it allows the effectiveness of the intervention evaluation and prediction of hand function in the postoperative period.
Fernanda Moreira Gomes Mehlmann   +5 more
doaj   +1 more source

Applicability of mitotic figure counting by deep learning: a development and pan‐cancer validation study

open access: yesFEBS Open Bio, EarlyView.
In this study, we developed a deep learning method for mitotic figure counting in H&E‐stained whole‐slide images and evaluated its prognostic impact in 13 external validation cohorts from seven different cancer types. Patients with more mitotic figures per mm2 had significantly worse patient outcome in all the studied cancer types except colorectal ...
Joakim Kalsnes   +32 more
wiley   +1 more source

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