A tumor-derived type III collagen-rich ECM niche regulates tumor cell dormancy
Nature Cancer, 2021 Cancer cells disseminate and seed in distant organs, where they can remain dormant for many years before forming clinically detectable metastases. Here we studied how disseminated tumor cells sense and remodel the extracellular matrix (ECM) to sustain ...
Julie S Di Martino +2 more
exaly +2 more sources
Astrocytic laminin-211 drives disseminated breast tumor cell dormancy in brain
Nature Cancer, 2021 Although dormancy is thought to play a key role in the metastasis of breast tumor cells to the brain, our knowledge of the molecular mechanisms regulating disseminated tumor cell (DTC) dormancy in this organ is limited.
Jinxiang Dai +2 more
exaly +2 more sources
Horticulturae, 2021 Adequate chill is of great importance for successful production of deciduous fruit trees. However, temperate fruit trees grown under tropical and subtropical regions may face insufficient winter chill, which has a crucial role in dormancy and ...
Abdel-Moety Salama +8 more
doaj +2 more sources
Combined transcriptomic and metabolomic analysis of the molecular mechanism of seed dormancy release in Notopterygium incisum [PDF]
BMC GenomicsBackground Notopterygium incisum seeds have both morphological and physiological dormancy characteristics and require stratification to break seed dormancy, but the mechanism of seed dormancy release during stratification is still unclear. In this study,
Wenlong Zhao +5 more
doaj +2 more sources
Stromal changes in the aged lung induce an emergence from melanoma dormancy
Nature, 2022 Mitchell E Fane +2 more
exaly +2 more sources
Bone marrow NG2+/Nestin+ mesenchymal stem cells drive DTC dormancy via TGF-β2
Nature Cancer, 2021 Ana Rita Nobre +2 more
exaly +2 more sources
Seed dormancy and the control of germination
New Phytologist, 2006 Gerhard Leubner-Metzger
exaly +2 more sources
The current paradigm and challenges ahead for the dormancy of disseminated tumor cells
Nature Cancer, 2020 Emma Risson +2 more
exaly +2 more sources
Evaluation the effect of gibberellic acid, carbon disulfide and thiourea on breaking the dormancy and germination of potato minitubers [PDF]
علوم و فناوری بذر ایران, 2020 Reducing the minituber dormancy has economic importance . The current study was aimed to find the best dormancy breaking treatment to reduce minituber dormancy of two commercial varieties (Sante and Agria).
shabnam hasrak +2 more
doaj +1 more source
A Modified Method to Assess Secondary Dormancy in the Seeds of Different Rapeseed Lines and Cultivars [PDF]
Journal of Genetic Resources, 2021 The exposure of seeds to undesirable soil conditions induces secondary dormancy and this causes many problems for seed producers. Assessing seed secondary dormancy potential is an important factor in developing rapeseed lines and cultivars.
Ali Shayanfar +4 more
doaj +1 more source