Results 91 to 100 of about 142,047 (308)

Anthropogenic seed dispersal: rethinking the origins of plant domestication

, 2020
It is well documented that ancient sickle harvesting led to tough rachises, but the other seed dispersal properties in crop progenitors are rarely discussed. The first steps toward domestication are evolutionary responses for the recruitment of humans as
Spengler, R.
core   +1 more source

Overview of molecular signatures of senescence and associated resources: pros and cons

FEBS Open Bio, EarlyView.
Cells can enter a stress response state termed cellular senescence that is involved in various diseases and aging. Detecting these cells is challenging due to the lack of universal biomarkers. This review presents the current state of senescence identification, from biomarkers to molecular signatures, compares tools and approaches, and highlights ...
Orestis A. Ntintas, Sylvia Vagena, Pavlos Pantelis, Giorgos Theocharous, Russel Petty, Konstantinos Evangelou, Vassilis G. Gorgoulis   +6 more
wiley   +1 more source

TFF3 facilitates dormancy of anti-estrogen treated ER+ mammary carcinoma

Communications Medicine
Background Tumor dormancy is a substantial clinical obstacle in treatment of estrogen receptor positive mammary carcinoma (ER+MC), contributing to drug resistance, metastatic outgrowth, relapse, and consequent mortality.
Shu Chen, Xi Zhang, Basappa Basappa, Tao Zhu, Vijay Pandey, Peter E. Lobie   +5 more
doaj   +1 more source

Overexpression of Prunus DAM6 inhibits growth, represses bud break competency of dormant buds and delays bud outgrowth in apple plants.

PLoS ONE, 2019
Most deciduous fruit trees cultivated in the temperate zone require a genotype-dependent amounts of chilling exposure for dormancy release and bud break.
Hisayo Yamane, Masato Wada, Chikako Honda, Takakazu Matsuura, Yoko Ikeda, Takashi Hirayama, Yutaro Osako, Mei Gao-Takai, Mikiko Kojima, Hitoshi Sakakibara, Ryutaro Tao   +10 more
doaj   +1 more source

Establishment of a coculture system for Porphyromonas gingivalis and head and neck squamous cell carcinoma using spheroid culture and LATS inhibition

FEBS Open Bio, EarlyView.
We established a spheroid coculture system enabling viable Porphyromonas gingivalis–HNSCC interactions under normoxic conditions. Inhibition of LATS1/2 maintains tumor cells in an undifferentiated state, which may promote spheroid growth and create a more permissive environment for bacterial persistence.
Yurika Nakajima, Shogo Okazaki, Muneaki Tamura, Shuichi Sato, Kenichi Imai   +4 more
wiley   +1 more source

HIV‐1 establishes immediate latency in T cells expressing the viral Nef protein

FEBS Open Bio, EarlyView.
Nef is a viral protein often omitted from HIV‐1 reporter viruses. Consequently, its role in viral latency is unclear. We developed three novel dual reporter HIV‐1 derivatives that express Nef and allow for detection of latent and productive infection. Using these reporters, we show that Nef does not affect the establishment of immediate viral latency ...
Cindy Lam, Ivan Sadowski
wiley   +1 more source

More than symbioses : orchid ecology ; with examples from the Sydney Region [PDF]

, 2013
The Orchidaceae are one of the largest and most diverse families of flowering plants. Orchids grow as terrestrial, lithophytic, epiphytic or climbing herbs but most orchids native to the Sydney Region can be placed in one of two categories.
Entwisle, Timothy J., Perkins, Andrew J., Weston, Peter H.   +2 more
core  

A laboratory simulation of Arabidopsis seed dormancy cycling provides new insight into its regulation by clock genes and the dormancy-related genes DOG1 , MFT , CIPK23 and PHYA [PDF]

, 2017
Environmental signals drive seed dormancy cycling in the soil to synchronise germination with the optimal time of year; a process essential for species fitness and survival.
Finch-Savage, William E., Footitt, Steven, Hambidge, Angela J., Ölcer-Footitt, Hülya   +3 more
core   +1 more source

The Aging Blood: Cellular Origins, Circulating Drivers, and Therapeutic Potential

Aging and Cancer, EarlyView.
As a conduit linking all organs, the blood system both reflects and actively drives systemic aging. This review highlights how circulating pro‐aging and antiaging factors and age‐associated hematopoietic stem cell dysfunction contribute to immunosenescence and multi‐organ decline, positioning the hematopoietic system as a target for aging intervention.
Hanqing He, Jianwei Wang
wiley   +1 more source

A transcriptome analysis reveals a role for the indole GLS-linked auxin biosynthesis in secondary dormancy in rapeseed (Brassica napus L.)

BMC Plant Biology, 2019
Background Brassica napus L. has little or no primary dormancy, but exhibits great variation in secondary dormancy. Secondary dormancy potential in oilseed rape can lead to the emergence of volunteer plants that cause genetic contamination, reduced ...
Lei Liu, Fuxia Liu, Jinfang Chu, Xin Yi, Wenqi Fan, Tang Tang, Guimin Chen, Qiuhuan Guo, Xiangxiang Zhao   +8 more
doaj   +1 more source