Results 101 to 110 of about 127,678 (374)

Tumor dormancy in bone

Cancer Reports, 2019
AbstractBackgroundBone marrow is a common site of metastasis for a number of tumor types, including breast, prostate, and lung cancer, but the mechanisms controlling tumor dormancy in bone are poorly understood. In breast cancer, while advances in drug development, screening practices, and surgical techniques have dramatically improved survival rates ...
Tolu Omokehinde, Rachelle W. Johnson, Rachelle W. Johnson, Vera Mayhew   +3 more
openaire   +4 more sources

I Want to (Bud) Break Free: The Potential Role of DAM and SVP-Like Genes in Regulating Dormancy Cycle in Temperate Fruit Trees

Frontiers in Plant Science, 2019
Bud dormancy is an adaptive process that allows trees to survive the hard environmental conditions that they experience during the winter of temperate climates.
V. S. Falavigna, Baptiste Guitton, E. Costes, F. Andrés   +3 more
semanticscholar   +1 more source

Autophagy inhibition elicits emergence from metastatic dormancy by inducing and stabilizing Pfkfb3 expression

Nature Communications, 2019
Breast cancer stem cells (BCSCs) are unique in their ability to undergo unlimited self-renewal, an essential process in breast cancer recurrence following metastatic dormancy.
Alyssa La Belle Flynn, B. Calhoun, Arishya Sharma, Jenny C. Chang, A. Almasan, W. Schiemann   +5 more
semanticscholar   +1 more source

Overexpression of Prunus DAM6 inhibits growth, represses bud break competency of dormant buds and delays bud outgrowth in apple plants.

PLoS ONE, 2019
Most deciduous fruit trees cultivated in the temperate zone require a genotype-dependent amounts of chilling exposure for dormancy release and bud break.
Hisayo Yamane, Masato Wada, Chikako Honda, Takakazu Matsuura, Yoko Ikeda, Takashi Hirayama, Yutaro Osako, Mei Gao-Takai, Mikiko Kojima, Hitoshi Sakakibara, Ryutaro Tao   +10 more
doaj   +1 more source

A pH-driven transition of the cytoplasm from a fluid- to a solid-like state promotes entry into dormancy

eLife, 2016
Cells can enter into a dormant state when faced with unfavorable conditions. However, how cells enter into and recover from this state is still poorly understood. Here, we study dormancy in different eukaryotic organisms and find it to be associated with
M. Munder, Daniel Midtvedt, Titus M. Franzmann, Elisabeth Nüske, O. Otto, M. Herbig, Elke Ulbricht, Paul Müller, Anna V. Taubenberger, Shovamayee Maharana, L. Malinovska, Doris Richter, J. Guck, V. Zaburdaev, S. Alberti   +14 more
semanticscholar   +1 more source

Capturing what matters: Patient‐reported LGI1‐ANTibody encephalitis outcome RatiNg scale (LANTERN)

Annals of Clinical and Translational Neurology, EarlyView.
Abstract Background LGI1‐antibody encephalitis (LGI1‐Ab‐E) is a common form of autoimmune encephalitis where most patients demonstrate ‘good’ clinician‐rated outcomes. However, more targeted questionnaires reveal numerous debilitating symptoms for many years.
Mark J Kelly, Barbara Wagner, Bryan Ceronie, Christine Strippel, Ann Yee Lin, Adam Handel, John Soltys, Sophie Binks, Philip A Powell, Sarosh R Irani   +9 more
wiley   +1 more source

Stromal changes in the aged lung induce an emergence from melanoma dormancy

Nature, 2022
Mitchell E. Fane, Yash Chhabra, Gretchen M. Alicea, Devon A. Maranto, Stephen M. Douglass, Marie R. Webster, V. Rebecca, Gloria E. Marino, Filipe V Almeida, B. Ecker, Daniel J. Zabransky, Laura Hüser, T. Beer, Hsin-Yao Tang, A. Kossenkov, M. Herlyn, D. Speicher, Wei Xu, Xiaowei Xu, E. Jaffee, J. Aguirre-Ghiso, A. Weeraratna   +21 more
semanticscholar   +1 more source

Associations of Cerebrospinal Fluid Orexin‐A, Alzheimer Disease Biomarkers, and Cognitive Performance

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACTObjectiveCerebrospinal fluid (CSF) orexin‐A has been suggested to be a biomarker of Alzheimer disease (AD). In both cognitively unimpaired healthy older adults and individuals with symptomatic AD, CSF orexin‐A is positively associated with CSF Aβ42, p‐tau181, and total tau (t‐tau) concentrations.
Ruijin Lu, Krish Shah, Cristina D. Toedebusch, Ashley Hess, Rachel Richardson, Emmanuel Mignot, Suzanne E. Schindler, Tammie L. S. Benzinger, Shaney Flores, Jason Hassenstab, Chengjie Xiong, John C. Morris, David M. Holtzman, Brendan P. Lucey   +13 more
wiley   +1 more source

Weedy Adaptation in Setaria spp.: VII. Seed Germination Heteroblasty in Setaria faberi [PDF]

arXiv, 2014
The dormancy status of S. faberi seed at abscission was assessed with reference to tiller and panicle development. Seed from a single genetic line were grown under field, greenhouse and controlled environment growth chamber conditions. At abscission, a small fraction (<10%) of S. faberi seed germinated under favorable conditions.
arxiv  

Dormancy of cutaneous melanoma

Cancer Cell International
AbstractMany cancer-related deaths including melanoma result from metastases that develop months or years after the initial cancer therapy. Even the most effective drugs and immune therapies rarely eradicate all tumor cells. Instead, they strongly reduce cancer burden, permitting dormant cancer cells to persist in niches, where they establish a ...
Kathrin Singvogel, Birgit Schittek
openaire   +3 more sources