Results 121 to 130 of about 223,726 (400)

Dormancy of cutaneous melanoma

Cancer Cell International
AbstractMany cancer-related deaths including melanoma result from metastases that develop months or years after the initial cancer therapy. Even the most effective drugs and immune therapies rarely eradicate all tumor cells. Instead, they strongly reduce cancer burden, permitting dormant cancer cells to persist in niches, where they establish a ...
Singvogel, Kathrin, Schittek, Birgit
openaire   +4 more sources

Overexpression of Prunus DAM6 inhibits growth, represses bud break competency of dormant buds and delays bud outgrowth in apple plants.

PLoS ONE, 2019
Most deciduous fruit trees cultivated in the temperate zone require a genotype-dependent amounts of chilling exposure for dormancy release and bud break.
Hisayo Yamane, Masato Wada, Chikako Honda, Takakazu Matsuura, Yoko Ikeda, Takashi Hirayama, Yutaro Osako, Mei Gao-Takai, Mikiko Kojima, Hitoshi Sakakibara, Ryutaro Tao   +10 more
doaj   +1 more source

Models of Microbial Dormancy in Biofilms and Planktonic Cultures

, 2010
We present models of dormancy in a planktonic culture and in biofilm, and examine the relative advantage of short dormancy versus long dormancy times in each case.
Ayati, Bruce P., Klapper, Isaac
core  

Actionable Wearables Data for the Neurology Clinic: A Proof‐of‐Concept Tool

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Wearable devices can monitor key health and fitness domains. In multiple sclerosis (MS), monitoring step count and sleep is feasible, valid, and offers a holistic glimpse of patient functioning and worsening. However, data generated from wearables are typically unavailable at the point of care.
Nicolette Miller, Ebenezer Chinedu‐Eneh, Jaeleene Wijangco, Kyra Henderson, Nikki Sisodia, Narender Sara, Jennifer Reihm, Shane Poole, Jim Rowson, Chu‐Yueh Guo, Jeffrey M. Gelfand, Valerie J. Block, Riley Bove   +12 more
wiley   +1 more source

TFF3 facilitates dormancy of anti-estrogen treated ER+ mammary carcinoma

Communications Medicine
Background Tumor dormancy is a substantial clinical obstacle in treatment of estrogen receptor positive mammary carcinoma (ER+MC), contributing to drug resistance, metastatic outgrowth, relapse, and consequent mortality.
Shu Chen, Xi Zhang, Basappa Basappa, Tao Zhu, Vijay Pandey, Peter E. Lobie   +5 more
doaj   +1 more source

A pH-driven transition of the cytoplasm from a fluid- to a solid-like state promotes entry into dormancy

eLife, 2016
Cells can enter into a dormant state when faced with unfavorable conditions. However, how cells enter into and recover from this state is still poorly understood. Here, we study dormancy in different eukaryotic organisms and find it to be associated with
M. Munder, Daniel Midtvedt, Titus M. Franzmann, Elisabeth Nüske, O. Otto, M. Herbig, Elke Ulbricht, Paul Müller, Anna V. Taubenberger, Shovamayee Maharana, L. Malinovska, Doris Richter, J. Guck, V. Zaburdaev, S. Alberti   +14 more
semanticscholar   +1 more source

Active Seizures Predict Worse Instrumental Activities of Daily Living in Individuals With Normal Cognition and Dementia

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives Cognitive disorders are common in older persons with seizures (PWS). Cognitive disorders are often associated with impaired Instrumental Activities of Daily Living (IADLs). However, the effects of seizures on IADLs remain unexplored.
Ifrah Zawar, Jaideep Kapur, Meghan M. Mattos, Carol Manning, Syeda Amrah Hashmi, Mark Quigg   +5 more
wiley   +1 more source

Mechanism of endocarp-imposed constraints of germination of Lannea microcarpa seeds [PDF]

, 2008
Lannea microcarpa, a multipurpose tree species from the dry African savanna, sheds seeds that often display inhibition of germination. The underlying mechanism was investigated using seeds processed from fully matured fruits collected from natural stands
Golovina, E.A., Hoekstra, F.A., Neya, O.
core   +2 more sources

Control of seed dormancy and germination by DOG1-AHG1 PP2C phosphatase complex via binding to heme

Nature Communications, 2018
Abscisic acid (ABA) regulates abiotic stress and developmental responses including regulation of seed dormancy to prevent seeds from germinating under unfavorable environmental conditions. ABA HYPERSENSITIVE GERMINATION1 (AHG1) encoding a type 2C protein
N. Nishimura, W. Tsuchiya, J. Moresco, Yuki Hayashi, Kouji Satoh, Nahomi Kaiwa, Tomoko Irisa, T. Kinoshita, J. Schroeder, J. Yates, T. Hirayama, T. Yamazaki   +11 more
semanticscholar   +1 more source

Cognitive and Patient‐Reported Outcome Measures in LGI‐1‐IgG Autoimmune Encephalitis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Clinical outcome measures for autoimmune encephalitis (AE) are not yet well defined. Cognitive outcome measures (CogOs) and patient‐reported outcomes (PROs) may capture the symptoms of AE, beyond clinician‐reported outcomes (ClinROs) (the Modified Rankin Scale [mRS] and Clinical Assessment Scale in Autoimmune Encephalitis [CASE ...
Tatchaporn Ongphichetmetha, Carol Swetlik, Nicolas Thompson, Albert Aboseif, Vineet Punia, Brittany Lapin, Jeffrey A. Cohen, Rachel Galioto, Amy Kunchok   +8 more
wiley   +1 more source