Results 121 to 130 of about 229,236 (394)

Translating a Preclinically Tested 15 Hz rTMS Protocol to Humans With Chronic Spinal Cord Injury: A Safety and Feasibility Study

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives Repetitive transcranial magnetic stimulation (rTMS) is a non‐invasive brain stimulation strategy with a demonstrated potential to reinforce the residual pathways after a spinal cord injury (SCI). A preclinically tested high‐frequency (15 Hz) rTMS (15 Hz rTMS) protocol was shown to induce corticospinal tract axon regeneration growth ...
Nabila Brihmat   +8 more
wiley   +1 more source

Breast Cancer Stem Cells as Drivers of Tumor Chemoresistance, Dormancy and Relapse: New Challenges and Therapeutic Opportunities

open access: yesCancers, 2019
Breast cancer is the most frequent cancer among women worldwide. Therapeutic strategies to prevent or treat metastatic disease are still inadequate although great progress has been made in treating early-stage breast cancer. Cancer stem-like cells (CSCs)
M. D. De Angelis   +2 more
semanticscholar   +1 more source

Development and germination of Sandersonia aurantiaca (Hook.) seeds : a thesis presented in partial fulfilment of the requirements for the degree of Master of Science in Plant Biology and Biotechnology at Massey University [PDF]

open access: yes, 1996
Sandersonia aurantiaca (Hook.) has recently become an important horticultural crop through its economic value for export of its cut flowers and tubers.
Zou, Xiuying
core  

Dormancy of cutaneous melanoma

open access: yesCancer Cell International
AbstractMany cancer-related deaths including melanoma result from metastases that develop months or years after the initial cancer therapy. Even the most effective drugs and immune therapies rarely eradicate all tumor cells. Instead, they strongly reduce cancer burden, permitting dormant cancer cells to persist in niches, where they establish a ...
Singvogel, Kathrin, Schittek, Birgit
openaire   +4 more sources

Chronic Pain in Parkinson’s Disease: Prevalence, Sex Differences, Regional Anatomy and Comorbidities

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
Chronic pain affected 66.2% of 10,631 individuals with Parkinson's disease, with higher prevalence and severity in females. Pain most often involved the buttocks, lower back, neck, and knees, and was linked to depression, sleep disorders, and osteoarthritis.
Natalia S. Ogonowski   +13 more
wiley   +1 more source

Winter Survival of Grasses and Legumes in Subarctic Alaska as Related to Latitudinal Adaptation, Pre-Winter Storage of Food Reserves, and Dry-Matter Concentration in Overwintering Tissues [PDF]

open access: yes, 1993
similar experiments, were to (a) compare winter hardiness in subarctic Alaska of numerous plant species and ecotypes from various latitudinal sources within most species, and (b) seek a better understanding of certain aspects of pre-winter ...
Klebesadel, Leslie J.
core  

Genetic Modifiers of Parkinson's Disease: A Case–Control Study

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To examine the associations of LRRK2 p.G2019S, GBA1 p.N409S, polygenic risk scores (PRS), and APOE E4 on PD penetrance, risk, and symptoms. Methods We conducted a US‐based observational case–control study using data from the 23andMe Inc. and Fox Insight Genetic Substudy (FIGS) databases.
Matthew J. Kmiecik   +15 more
wiley   +1 more source

TFF3 facilitates dormancy of anti-estrogen treated ER+ mammary carcinoma

open access: yesCommunications Medicine
Background Tumor dormancy is a substantial clinical obstacle in treatment of estrogen receptor positive mammary carcinoma (ER+MC), contributing to drug resistance, metastatic outgrowth, relapse, and consequent mortality.
Shu Chen   +5 more
doaj   +1 more source

Autophagy inhibition elicits emergence from metastatic dormancy by inducing and stabilizing Pfkfb3 expression

open access: yesNature Communications, 2019
Breast cancer stem cells (BCSCs) are unique in their ability to undergo unlimited self-renewal, an essential process in breast cancer recurrence following metastatic dormancy.
Alyssa La Belle Flynn   +5 more
semanticscholar   +1 more source

The transcriptome of Mycobacterium tuberculosis in a lipid-rich dormancy model through RNAseq analysis [PDF]

open access: yes, 2017
Tuberculosis (TB) is currently the number one killer among infectious diseases worldwide. Lipids are abundant molecules during the infectious cycle of Mycobacterium tuberculosis (Mtb) and studies better mimicking its actual metabolic state during ...
Aguilar-Ayala, Diana   +7 more
core   +2 more sources

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