This study investigates the role of protein arginine methyltransferase 1 (PRMT1) in endothelial cells (ECs) in chronic obstructive pulmonary disease (COPD). Mice with endothelial‐specific PRMT1 deletion develop pulmonary hemorrhage, inflammation, and apoptosis, driven by excessive nuclear factor kappa B activation.
Thi Thuy Vy Tran+7 more
wiley +1 more source
Transcriptome analysis to explore the molecular mechanisms involved in the dormancy-arousal process in Pomacea canaliculata (Lamarck, 1819). [PDF]
Wang G+15 more
europepmc +1 more source
Epileptiform Activity and Seizure Risk Follow Long‐Term Non‐Linear Attractor Dynamics
This study leverages the HAVOK framework to model long‐term, nonlinear attractor dynamics underlying epileptiform activity and seizure risk in epilepsy patients. By identifying key forcing mechanisms driving chaotic transitions, the findings improve seizure risk forecasting over multi‐day cycles and provide a pathway for personalized, data‐driven ...
Richard E Rosch+4 more
wiley +1 more source
A Molecularly Defined Medullary Network for Control of Respiratory Homeostasis
The dynamic interplay between central respiratory chemoreceptors and the respiratory central pattern generator is essential for maintaining stable respiratory rhythm and patterns, particularly during sleep. This study offers novel insights into the anatomical, molecular, and functional characteristics of a medullary network involving the nucleus ...
Tianjiao Deng+16 more
wiley +1 more source
After-Ripening Is Associated with Changes in the Sensitivity of Avena fatua L. Caryopses to Abscisic Acid, as Well as Changes in the Abscisic Acid and Bioactive Gibberellins Contents in Embryos. [PDF]
Kępczyński J, Wójcik A, Dziurka M.
europepmc +1 more source
On the Relation between the Change of Respiratory System and the Dormancy of Potato Tubers
Yasunao Nishiyama, Takashi Tagawa
openalex +2 more sources
Histone Deacetylase 6 (HDAC6) in Ciliopathies: Emerging Insights and Therapeutic Implications
HDAC6 regulates primary cilia, crucial for cellular signalling and environmental responses. Dysregulation of HDAC6 contributes to ciliopathies, affecting multiple organs. This review examines HDAC6's role in ciliogenesis, its interaction with signaling molecules, and its potential as a therapeutic target.
Zhiyi Wang+5 more
wiley +1 more source
Apoptotic cell-derived extracellular vesicles-MTA1 confer radioresistance in cervical cancer by inducing cellular dormancy. [PDF]
Deng YR+8 more
europepmc +1 more source
The Fe3O4/Gd@BSA‐pPB nanoprobe leverages biomimetic mineralization and targets hepatic stellate cells (HSCs) through PDGFRβ, offering superior enrichment in fibrotic regions. This targeted delivery overcomes biological barriers, enhancing both the accuracy and sensitivity of MRI imaging at early disease stages.
Zehua Li+11 more
wiley +1 more source