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Metastasis is the primary cause of death in cancer patients and current treatments fail to provide durable responses. Efforts to treat metastatic disease are hindered by the fact that metastatic cells often remain dormant for prolonged intervals of years, or even decades.
Gomis i Cabré, Roger, Gawrzak, Sylwia
openaire +4 more sources
The Relationship Between Mesenchymal Stem Cells and Tumor Dormancy
Tumor dormancy, a state of tumor, is clinically undetectable and the outgrowth of dormant tumor cells into overt metastases is responsible for cancer-associated deaths.
Linxian Zhao+6 more
doaj +1 more source
Seed Dormancy and Germination [PDF]
Seed dormancy allows seeds to overcome periods that are unfavourable for seedling established and is therefore important for plant ecology and agriculture. Several processes are known to be involved in the induction of dormancy and in the switch from the dormant to the germinating state.
Leónie Bentsink+2 more
openaire +7 more sources
Regulation of Seed Dormancy and Germination Mechanisms in a Changing Environment
Environmental conditions are the basis of plant reproduction and are the critical factors controlling seed dormancy and germination. Global climate change is currently affecting environmental conditions and changing the reproduction of plants from seeds.
Ewelina A Klupczyńska, T. Pawłowski
semanticscholar +1 more source
Morphological and anatomical changes during dormancy break of the seeds of Fritillaria taipaiensis
Fritillaria taipaiensis P. Y. Li is the most suitable species planted at low altitudes among other species used as Tendrilleaf Fritillary Bulb, whose seeds embracing the morphological and physiological dormancy need to experience a long-dormant time from
Min Luo+4 more
doaj +1 more source
Astrocytic laminin-211 drives disseminated breast tumor cell dormancy in brain
Although dormancy is thought to play a key role in the metastasis of breast tumor cells to the brain, our knowledge of the molecular mechanisms regulating disseminated tumor cell (DTC) dormancy in this organ is limited.
Jinxiang Dai+21 more
semanticscholar +1 more source
A potential biomarker of cognitive impairment: The olfactory dysfunction and its genes expression
Abstract Objective Accumulation evidence has reported that olfactory impairment may be an essential clinical marker and predictor of mild cognitive impairment or Alzheimer's disease. Method Participants were enrolled in the population‐based, prospective study in Fuxin county, Liaoning province, China between 2019 and 2021.
Jiayi Song+11 more
wiley +1 more source
A Perspective on Secondary Seed Dormancy in Arabidopsis thaliana
Primary seed dormancy is the phenomenon whereby seeds newly shed by the mother plant are unable to germinate under otherwise favorable conditions for germination.
Gonda Buijs
doaj +1 more source
Examination of Some Nut Traits and Release From Dormancy Along With Germination Capacity in Some Bitter Almond Genotypes [PDF]
This study was conducted at College of Agricultural Engineering Sciences, University of Sulaimani, Kurdistan Region-Iraq so as to investigate some nut traits in 10 bitter almond genotypes, capacity of them to release from dormancy and finally germination ability.
arxiv +1 more source
The clinical spectrum of SMA‐PME and in vitro normalization of its cellular ceramide profile
Abstract Objective The objectives of this study were to define the clinical and biochemical spectrum of spinal muscular atrophy with progressive myoclonic epilepsy (SMA‐PME) and to determine if aberrant cellular ceramide accumulation could be normalized by enzyme replacement.
Michelle M. Lee+16 more
wiley +1 more source