Proceedings of the National Academy of Sciences of the United States of America, 2017 Significance Increasing evidence suggests that extracellular vesicles (EVs) can transfer genetic material to recipient cells. However, the mechanism and role of this phenomenon are largely unknown. Here we have made a remarkable discovery: EVs can harbor
P. Sansone +20 more
semanticscholar +1 more source
Dormancy signatures and metastasis in estrogen receptor positive and negative breast cancer. [PDF]
PLoS ONE, 2012 Breast cancers can recur after removal of the primary tumor and treatment to eliminate remaining tumor cells. Recurrence may occur after long periods of time during which there are no clinical symptoms.
Ryung S Kim +6 more
doaj +1 more source
Environment sensing in spring-dispersed seeds of a winter annual Arabidopsis influences the regulation of dormancy to align germination potential with seasonal changes [PDF]
, 2014 Seed dormancy cycling plays a crucial role in the lifecycle timing of many plants. Little is known of how the seeds respond to the soil seed bank environment following dispersal in spring into the short-term seed bank before seedling emergence in autumn.
Clay, Heather A. +3 more
core +1 more source
Delay of germination-1 (DOG1): a key to understanding seed dormancy [PDF]
, 2020 [Abstract] DELAY OF GERMINATION-1 (DOG1), is a master regulator of primary dormancy (PD) that acts in concert with ABA to delay germination. The ABA and DOG1 signaling pathways converge since DOG1 requires protein phosphatase 2C (PP2C) to control PD ...
Carrillo Barral, Néstor +2 more
core +1 more source
Low temperature stimulates spatial molecular reprogramming of the Arabidopsis seed germination programme [PDF]
, 2021 The timing of the germination of seeds is highly responsive to inputs from the environment. Temperature plays a key role in the control of germination, with low temperatures acting to stimulate this developmental transition in many species.
Bassel, George +2 more
core +1 more source
Dormancy and germination: making every seed count in restoration
Restoration Ecology, 2020 From 50 to 90% of wild plant species worldwide produce seeds that are dormant upon maturity, with specific dormancy traits driven by species' occurrence geography, growth form, and genetic factors.
O. Kildisheva +7 more
semanticscholar +1 more source
When dormancy fuels tumour relapse
Communications Biology, 2021 Tumour recurrence is a serious impediment to cancer treatment, but the mechanisms involved are poorly understood. The most frequently used anti-tumour therapies—chemotherapy and radiotherapy—target highly proliferative cancer cells.
Karla Santos-de-Frutos, N. Djouder
semanticscholar +1 more source
Differential coupling of gibberellin responses by Rht-B1c suppressor alleles and Rht-B1b in wheat highlights a unique role for the DELLA N-terminus in dormancy [PDF]
, 2017 During the Green Revolution, substantial increases in wheat (Triticum aestivum) yields were realized, at least in part, through the introduction of the Reduced height (Rht)-B1b and Rht-D1b semi-dwarfing alleles.
Chandler, Peter Michael +3 more
core +1 more source
Agronomy, 2020 Loss of seed viability, poor and delayed germination, and inaccessibility to high-quality seeds are key bottlenecks limiting all-year-round production of African traditional leafy vegetables (TLVs).
Fernand S. Sohindji +4 more
doaj +1 more source
Principles of seed banks and the emergence of complexity from dormancy [PDF]
Nature Communications, 2020 Across the tree of life, populations have evolved the capacity to contend with suboptimal conditions by engaging in dormancy, whereby individuals enter a reversible state of reduced metabolic activity.
J. Lennon +3 more
semanticscholar +1 more source