Results 51 to 60 of about 128,870 (374)

A Cellular Automaton Model for Tumor Dormancy: Emergence of a Proliferative Switch [PDF]

open access: yesChen D, Jiao Y, Torquato S (2014) A Cellular Automaton Model for Tumor Dormancy: Emergence of a Proliferative Switch. PLoS ONE 9(10): e109934, 2014
Malignant cancers that lead to fatal outcomes for patients may remain dormant for very long periods of time. Although individual mechanisms such as cellular dormancy, angiogenic dormancy and immunosurveillance have been proposed, a comprehensive understanding of cancer dormancy and the "switch" from a dormant to a proliferative state still needs to be ...
arxiv   +1 more source

Models of Microbial Dormancy in Biofilms and Planktonic Cultures [PDF]

open access: yesCommun. Math. Sci., 10(2) pp. 493-511, 2012, 2010
We present models of dormancy in a planktonic culture and in biofilm, and examine the relative advantage of short dormancy versus long dormancy times in each case. Simulations and analyses indicate that in planktonic batch cultures and in chemostats, live biomass is maximized by the fastest possible exit from dormancy.
arxiv   +1 more source

Short day transcriptomic programming during induction of dormancy in grapevine

open access: yesFrontiers in Plant Science, 2015
Bud dormancy in grapevine is an adaptive strategy for the survival of drought, high and low temperatures and freeze dehydration stress that limit the range of cultivar adaptation.
Anne Y Fennell   +8 more
doaj   +1 more source

Long non-coding RNA NR2F1-AS1 induces breast cancer lung metastatic dormancy by regulating NR2F1 and ΔNp63

open access: yesNature Communications, 2021
Disseminated tumor cells often fall into a long term of dormant stage, characterized by decreased proliferation but sustained survival, in distant organs before awakening for metastatic growth. However, the regulatory mechanism of metastatic dormancy and
Yingjie Liu   +16 more
semanticscholar   +1 more source

Dormancy: There and Back Again

open access: yesMolecular Biology, 2022
Many cells are capable of maintaining viability in a non-dividing state with minimal metabolism under unfavorable conditions. These are germ cells, adult stem cells, and microorganisms. Unfortunately, a resting state, or dormancy, is possible for tuberculosis bacilli in a latent form of the disease and cancer cells, which may later form secondary ...
Pshennikova, E. S., Voronina, A. S.
openaire   +3 more sources

Understanding Molecular Mechanisms of Seed Dormancy for Improved Germination in Traditional Leafy Vegetables: An Overview

open access: yesAgronomy, 2020
Loss of seed viability, poor and delayed germination, and inaccessibility to high-quality seeds are key bottlenecks limiting all-year-round production of African traditional leafy vegetables (TLVs).
Fernand S. Sohindji   +4 more
doaj   +1 more source

Dormancy signatures and metastasis in estrogen receptor positive and negative breast cancer. [PDF]

open access: yesPLoS ONE, 2012
Breast cancers can recur after removal of the primary tumor and treatment to eliminate remaining tumor cells. Recurrence may occur after long periods of time during which there are no clinical symptoms.
Ryung S Kim   +6 more
doaj   +1 more source

Packaging and transfer of mitochondrial DNA via exosomes regulate escape from dormancy in hormonal therapy-resistant breast cancer

open access: yesProceedings of the National Academy of Sciences of the United States of America, 2017
Significance Increasing evidence suggests that extracellular vesicles (EVs) can transfer genetic material to recipient cells. However, the mechanism and role of this phenomenon are largely unknown. Here we have made a remarkable discovery: EVs can harbor
P. Sansone   +20 more
semanticscholar   +1 more source

The impact of dormancy on evolutionary branching [PDF]

open access: yesarXiv, 2022
In this paper, we investigate the consequences of dormancy in the `rare mutation' and `large population' regime of stochastic adaptive dynamics. Starting from an individual-based micro-model, we first derive the polymorphic evolution sequence of the population, based on previous work by Baar and Bovier (2018). After passing to a second `small mutations'
arxiv  

Dormancy and germination: making every seed count in restoration

open access: yesRestoration Ecology, 2020
From 50 to 90% of wild plant species worldwide produce seeds that are dormant upon maturity, with specific dormancy traits driven by species' occurrence geography, growth form, and genetic factors.
O. Kildisheva   +7 more
semanticscholar   +1 more source

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