Results 71 to 80 of about 229,236 (394)
From omics to AI—mapping the pathogenic pathways in type 2 diabetes
FEBS Letters, EarlyView.Integrating multi‐omics data with AI‐based modelling (unsupervised and supervised machine learning) identify optimal patient clusters, informing AI‐driven accurate risk stratification. Digital twins simulate individual trajectories in real time, guiding precision medicine by matching patients to targeted therapies.
Siobhán O'Sullivan +2 more
wiley +1 more source
Delayed Germination of Seeds: A Look at the Effects of Adult Longevity, the Timing of Reproduction, and Population Age/Stage Structure [PDF]
, 1994 The effects of adult longevity, the timing of reproduction, and population age/stage structure on the evolution of seed dormancy are explored in both constant and variable environment models. In the constant environment models complete germination is the
Rees, M.
core +1 more source
Tumor dormancy and immunoescape [PDF]
APMIS, 2008 The role of the immune system in tumor dormancy is now well established. In several experimental models it is possible to induce tumor dormancy in immunocompetent hosts by prior immunization against tumor cells. Equilibrium between immune response and tumor cells leads to long‐term tumor dormancy.
Bruno Quesnel, Bruno Quesnel
openaire +3 more sources
FEBS Letters, EarlyView.Single‐cell RNA sequencing reveals an opposite role of SLPI in basal tumors based on metastatic spread, along with shared activation of specific regulons in cancer cells and mature luminal lactocytes, as well as downregulation of MALAT1 and NEAT1 in the latter.
Pietro Ancona +4 more
wiley +1 more source
The RNA-seq transcriptome analysis identified genes related to rice seed dormancy
Biologia Plantarum, 2019 Plant hormones play important roles in seed dormancy and dormancy breaking. We measured the hormone content in rice (Oryza sativa L. cv. Nona Bokra) seeds at different stages and with or without imbibition treatment.
K. Xie +7 more
doaj +1 more source
Inhibition of DEC2 is necessary for exiting cell dormancy in salivary adenoid cystic carcinoma
Journal of Experimental & Clinical Cancer Research, 2021 Background Patients were prone to have poor prognosis once dormant tumor cells being reactivated. However, the molecular mechanism of tumor cell dormancy remains poorly understood.
Xiao Yang +10 more
doaj +1 more source
Improvement of seed germination of Fagus orientalis Lipsky [PDF]
, 2003 This thesis was seeking two main approaches for improvement of seed germination of oriental beech, a timber producing species in Hyrcanian forests in northern Iran. Germination behavior of beechnuts was enhanced either by decreasing the dormancy breakage
Soltani, Ali
core
, 2007 The term ‘dormancy’ refers to a state of a plant or plantorgan that is characterized by the virtual absence of met-abolic activity and/or a lack of further development andgrowth.Dormancyoccursinseeds,bulbs,tubers,budsandwhole plants. It is an adaptive trait that has evolved byselection for the capacity to survive prolonged unfavour-able environmental ...
Hilhorst, H.W.M., Koornneef, M.
openaire +3 more sources
Imeglimin attenuates liver fibrosis by inhibiting vesicular ATP release from hepatic stellate cells
FEBS Letters, EarlyView.Imeglimin, at clinically relevant concentrations, inhibits vesicular ATP accumulation and release from hepatic stellate cells, thereby attenuating purinergic signaling and reducing fibrogenic activation. This mechanism reveals a newly identified antifibrotic action of imeglimin beyond glycemic control.
Seiji Nomura +8 more
wiley +1 more source
Recent Insights into Mechanisms Governing Breast Cancer Dormancy
Zhongliu Fangzhi Yanjiu, 2023 Tumor dormancy refers to the status of disseminated cancer cells that remain in a viable yet not proliferating state for a prolonged period. Dormant cells will eventually "re-awake" resume their proliferation, and produce overt metastasis.
MA Lanjing, ZHANG Baihong
doaj +1 more source