Results 71 to 80 of about 128,870 (374)

Recent Insights into Mechanisms Governing Breast Cancer Dormancy

open access: yesZhongliu Fangzhi Yanjiu, 2023
Tumor dormancy refers to the status of disseminated cancer cells that remain in a viable yet not proliferating state for a prolonged period. Dormant cells will eventually "re-awake" resume their proliferation, and produce overt metastasis.
MA Lanjing, ZHANG Baihong
doaj   +1 more source

The signalling role of ROS in the regulation of seed germination and dormancy.

open access: yesBiochemical Journal, 2019
Reactive oxygen species (ROS) are versatile compounds which can have toxic or signalling effects in a wide range living organisms, including seeds. They have been reported to play a pivotal role in the regulation of seed germination and dormancy but ...
C. Bailly
semanticscholar   +1 more source

FoxO1 signaling in B cell malignancies and its therapeutic targeting

open access: yesFEBS Letters, EarlyView.
FoxO1 has context‐specific tumor suppressor or oncogenic character in myeloid and B cell malignancies. This includes tumor‐promoting properties such as stemness maintenance and DNA damage tolerance in acute leukemias, or regulation of cell proliferation and survival, or migration in mature B cell malignancies.
Krystof Hlavac   +3 more
wiley   +1 more source

Physical Seed Dormancy in Legumes: Molecular Advances and Perspectives

open access: yesPlants
Physical dormancy of seeds is a form of dormancy due to the presence of an impermeable seed coat layer, and it represents a feature for plants to adapt to environmental changes over an extended period of phylogenetic evolution.
Zhaozhu Wen   +4 more
doaj   +1 more source

QTL mapping for microtuber dormancy and GA3 content in a diploid potato population

open access: yesBiology Open, 2018
The genetic control of dormancy is poorly understood in most plant species, but dormancy is a prominent feature for the potato industry. We used the microtuber system, in which tubers were produced in vitro and stored at 20°C, to perform quantitative ...
Raja Mohib Muazzam Naz   +6 more
doaj   +1 more source

Inhibition of DEC2 is necessary for exiting cell dormancy in salivary adenoid cystic carcinoma

open access: yesJournal of Experimental & Clinical Cancer Research, 2021
Background Patients were prone to have poor prognosis once dormant tumor cells being reactivated. However, the molecular mechanism of tumor cell dormancy remains poorly understood.
Xiao Yang   +10 more
doaj   +1 more source

The immunological interface: dendritic cells as key regulators in metabolic dysfunction‐associated steatotic liver disease

open access: yesFEBS Letters, EarlyView.
Metabolic dysfunction‐associated steatotic liver disease (MASLD) affects nearly one‐third of the global population and poses a significant risk of progression to cirrhosis or liver cancer. Here, we discuss the roles of hepatic dendritic cell subtypes in MASLD, highlighting their distinct contributions to disease initiation and progression, and their ...
Camilla Klaimi   +3 more
wiley   +1 more source

Seed Dormancy Class and Ecophysiological Features of Veronicastrum sibiricum (L.) Pennell (Scrophulariaceae) Native to the Korea Peninsula

open access: yesPlants, 2022
Veronicastrum sibiricum is a perennial species distributed in Korea, Japan, Manchuria, China, and Siberia. This study aimed to determine the requirements for germination and dormancy break of V.
Gyeong Ho Jang   +3 more
doaj   +1 more source

Insights into PI3K/AKT signaling in B cell development and chronic lymphocytic leukemia

open access: yesFEBS Letters, EarlyView.
This Review explores how the phosphoinositide 3‐kinase and protein kinase B pathway shapes B cell development and drives chronic lymphocytic leukemia, a common blood cancer. It examines how signaling levels affect disease progression, addresses treatment challenges, and introduces novel experimental strategies to improve therapies and patient outcomes.
Maike Buchner
wiley   +1 more source

Sowing seeds for the future: the need for establishing protocols for the study of seed dormancy

open access: yesActa Botânica Brasílica, 2013
Seed dormancy is a widely misunderstood plant trait. In several research areas, a lack of germination is wrongly assumed to result from seed dormancy. In an attempt to standardize seed dormancy research and improve communication among seed scientists, a ...
Fernando Augusto Oliveira Silveira
doaj   +1 more source

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