Results 81 to 90 of about 229,236 (394)

Cytomegalovirus infection is common in prostate cancer and antiviral therapies inhibit progression in disease models

open access: yesMolecular Oncology, EarlyView.
Human cytomegalovirus infection is common in normal prostate epithelium, prostate tumor tissue, and prostate cancer cell lines. CMV promotes cell survival, proliferation, and androgen receptor signaling. Anti‐CMV pharmaceutical compounds in clinical use inhibited cell expansion in prostate cancer models in vitro and in vivo, motivating investigation ...
Johanna Classon   +13 more
wiley   +1 more source

Seed dormancy release of Halenia elliptica in response to stratification temperature, duration and soil moisture content

open access: yesBMC Plant Biology, 2020
Background Although the effect of cold stratification on seed dormancy release has been extensively studied for many species, knowledge of the role of stratifying temperature, soil moisture content and duration of stratification on seed dormancy release ...
Da Li Chen   +4 more
doaj   +1 more source

The role of light in regulating seed dormancy and germination.

open access: yesJournal of Integrative Plant Biology, 2020
Seed dormancy is an adaptive trait in plants. Breaking seed dormancy determines the timing of germination and is, thereby essential for ensuring plant survival and agricultural production.
Liwen Yang   +2 more
semanticscholar   +1 more source

A molecular timetable for apical bud formation and dormancy induction in poplar [PDF]

open access: yes, 2007
The growth of perennial plants in the temperate zone alternates with periods of dormancy that are typically initiated during bud development in autumn. In a systems biology approach to unravel the underlying molecular program of apical bud development in
Arend, Matthias   +8 more
core   +2 more sources

Dormancy in breast cancer

open access: yesBreast Cancer: Targets and Therapy, 2012
Tumor dormancy describes a prolonged quiescent state in which tumor cells are present, but disease progression is not yet clinically apparent. Breast cancer is especially known for long asymptomatic periods, up to 25 years, with no evidence of the disease, followed by a relapse.
Tanja Fehm   +6 more
openaire   +5 more sources

The critical role of DNA damage‐inducible transcript 4 (DDIT4) in stemness character of leukemia cells and leukemia initiation

open access: yesMolecular Oncology, EarlyView.
Stemness properties, including quiescence, self‐renewal, and chemoresistance, are closely associated with leukemia relapse. Here, we demonstrate that DNA damage‐inducible transcript 4 (DDIT4) is induced in the hypoxic bone marrow niche and is essential for maintaining the stemness of AML1‐ETO9a leukemia cells.
Yishuang Li   +12 more
wiley   +1 more source

Dormancy release of seeds of Podophyllum hexandrum Royle accompanied by changes in phytochemicals and inorganic elements.

open access: yesPLoS ONE, 2023
Podophyllum hexandrum Royle is an alpine medicinal plant of considerable importance, and its seed dormancy severely inhibits population renewal. Although cold stratification can break dormancy to a certain extent, the migration and accumulation of ...
Xijia Jiu   +6 more
doaj   +1 more source

YAP1::TFE3 mediates endothelial‐to‐mesenchymal plasticity in epithelioid hemangioendothelioma

open access: yesMolecular Oncology, EarlyView.
The YAP1::TFE3 fusion protein drives endothelial‐to‐mesenchymal transition (EndMT) plasticity, resulting in the loss of endothelial characteristics and gain of mesenchymal‐like properties, including resistance to anoikis, increased migratory capacity, and loss of contact growth inhibition in endothelial cells.
Ant Murphy   +9 more
wiley   +1 more source

Decoupling photo- and thermoperiod by projected climate change perturbs bud development, dormancy establishment and vernalization in the model tree Populus

open access: yesBMC Plant Biology, 2018
Background The performance and survival of deciduous trees depends on their innate ability to anticipate seasonal change. A key event is the timely production of short photoperiod-induced terminal and axillary buds that are dormant and freezing-tolerant.
Päivi L. H. Rinne   +2 more
doaj   +1 more source

Dormancy in reproductive vegetative buds in creeping perennials dominating the agricultural weed flora in Scandinavia [PDF]

open access: yes, 2013
Dormancy, which is the inability to initiate normal growth under otherwise favourable conditions, is an adaptation to escape sprouting prior to seasonal cold temperatures and/or drought in areas where winters are harsh or summers dry.
Liew, Josefine
core  

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