Results 41 to 50 of about 402,447 (218)

Stage-specific functional networks associated with cognitive impairment in Parkinson's disease: a pilot fNIRS study

Frontiers in Aging Neuroscience
ObjectiveThis study aimed to investigate cortical activation and functional connectivity during Stroop task performance in Parkinson's disease (PD) using functional near-infrared spectroscopy (fNIRS).MethodsForty-five individuals with PD and fourteen ...
Jiarui Zhao, Yulai Gong, Zhenfang Lin, Jie Yang, Jiahuan Zou, Xia He, Yongsheng He   +6 more
doaj   +1 more source

Distinct contributions of the dorsolateral prefrontal and orbitofrontal cortex during emotion regulation. [PDF]

PLoS ONE, 2012
The lateral prefrontal and orbitofrontal cortices have both been implicated in emotion regulation, but their distinct roles in regulation of negative emotion remain poorly understood.
Armita Golkar, Tina B Lonsdorf, Andreas Olsson, Kara M Lindstrom, Jonathan Berrebi, Peter Fransson, Martin Schalling, Martin Ingvar, Arne Öhman   +8 more
doaj   +1 more source

Regulation of Craving: Neural Correlates and the Role of Stress and Delay Discounting. [PDF]

Addict Biol
Sixty‐eight male smokers underwent delay discounting and stress/control conditions before completing a regulation of craving (ROC) task during fMRI. Focusing on long‐term negative consequences was associated with reduced subjective craving and lower ventral striatum and vmPFC activity, as well as higher dlPFC activation, compared with focusing on short‐
Nickel-Grenke S, Wüllhorst R, Scherbaum S, Schwarz K, Endrass T.   +4 more
europepmc   +2 more sources

Neural correlates of map representation and spatial orientation in orienteering experts: an fNIRS study

Frontiers in Human Neuroscience
This study investigated the neural mechanisms underlying spatial navigation expertise in orienteering using a mixed-factorial design with skill level (expert vs. novice) as a between-subjects factor and map orientation (normal vs.
Long Wang, Shi Jia Ou, Yang Liu
doaj   +1 more source

The representation of abstract task rules in the human prefrontal cortex [PDF]

, 2009
We have previously reported sustained activation in the ventral prefrontal cortex while participants prepared to perform 1 of 2 tasks as instructed.
Haynes, J., Sakai, K., Sara L. Bengtsson, Sakai, K, Buckley, M., Buckley, Mark J., Passingham, Richard E., Passingham, RE, Passingham, Richard, Bengtsson, S. L., John-dylan Haynes, Bengtsson, S., Buckley, Mark, Sakai, Katsuyuki, Haynes, John-Dylan, Buckley, M.J., Buckley, MJ, Bengtsson, Sara L., Richard E. Passingham, Haynes, J.-D., Passingham, R., Passingham, R.E., Bengtsson, SL, Mark J. Buckley, Katsuyuki Sakai, Haynes, JD   +25 more
core   +1 more source

STWave: Fine‐Scale Spatial Structure Discovery in Microscopic‐Resolution Spatial Transcriptomics via Patchwise Wavelet Graphs

Advanced Science, EarlyView.
STWave transforms massive microscopic‐resolution spatial transcriptomics into interpretable fine‐scale tissue maps through patch‐wise inference, wavelet‐based multi‐scale encoding, and dual‐domain reconstruction. It reduces noise while preserving weak spatial signals, enabling efficient analysis of 6 40 000 spots of 2.47 GB GPU memory and revealing ...
Tao Jiang, Songming Zhang, Xiaofeng Chen, Xiongtao Xiao, Wenming Cao, Weikai Li, Tong Zhao, Bing Li, Xinyue Xu, Zhongshan Li   +9 more
wiley   +1 more source

Dysbindin-1 in dorsolateral prefrontal cortex of schizophrenia cases is reduced in an isoform-specific manner unrelated to altered dysbindin-1 gene expression [PDF]

, 2009
DTNBP1 (dystrobrevin binding protein 1) remains one of the top candidate genes in schizophrenia. Reduced expression of this gene and the protein it encodes, dysbindin-1, has been reported in the dorsolateral prefrontal cortex (DLPFC) of schizophrenia ...
Natalia Louneva, Julia W. Cohen, Konrad Talbot, Chang-Gyu Hahn, Steven E. Arnold, Derek J. Blake, Junxia Tang, Lilly Yeh, Robert P. LeGros   +8 more
core  

A key role of the prefrontal cortex in the maintenance of chronic tinnitus: An fMRI study using a Stroop task

NeuroImage: Clinical, 2018
Introduction: Since we recently showed in behavioural tasks that the top-down cognitive control was specifically altered in tinnitus sufferers, here we wanted to establish the link between this impaired executive function and brain alterations in the ...
Rodrigo Araneda, Laurent Renier, Laurence Dricot, Monique Decat, Daniela Ebner-Karestinos, Naïma Deggouj, Anne G. De Volder   +6 more
doaj   +1 more source

The role of prefrontal cortex and temporoparietal junction in interpersonal comfort and emotional approach

Scientific Reports, 2023
Our perception of physical distance to individuals and stimuli is influenced by our mental distance and relatedness. The present study aimed to investigate the role of the dorsolateral prefrontal cortex (dlPFC), ventromedial prefrontal cortex (vmPFC ...
Vahid Nejati, Aylin Mardanpour, Abbas Zabihzaheh, Reza Estaji, Zahra S. Vaziri, Shahriar Shahidi   +5 more
doaj   +1 more source

Tau Aggregate Imaging and Transcriptomics of Alzheimer's Disease Brain at Different Stages of Disease

Advanced Science, EarlyView.
The protein aggregates and gene expression in the middle temporal gyrus (MTG) and somatosensory cortex (SOM) of the postmortem brains of 13 Alzheimer's disease patients were studied in detail, revealing that small hyperphosphorylated tau aggregates increase with Braak stage driven by microglial inflammation.
Elizabeth A. English, Dorothea Böken, Matthew W. Cotton, Matthew R. Cheetham, Johanna S. Jackson, Georg Meisl, John S. H. Danial, Paul M. Matthews, Nurun N. Fancy, David Klenerman   +9 more
wiley   +1 more source