Results 91 to 100 of about 5,022,010 (310)

Aplicações da Cultura In vitro na Propagação de Espécies Endémicas dos Açores: A Investigação Aplicada como Prática de Ensino

open access: yes, 2012
XV Expedição Científica do Departamento de Biologia - São Jorge 2011.O texto apresentado corresponde à síntese da palestra apresentada a 27 de julho de 2011 no Salão da Sociedade Filarmónica Urzelinense durante a expedição científica realizada à ilha de ...
Pereira, Maria J.
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Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

Caracterização do perfil dos empreendedores e empreendimentos do centro comercial de Serrinha dos Pintos-RN

open access: yes, 2018
MonografiaEntrepreneurship has been a relevant theme in Brazil and in the world, since this has been the motor that drives economic development and job creation income.
Santos, Cosma Daniela dos
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The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

Levantamento e caracterização dos poços subterrâneos na cidade de Pau dos Ferros - RN

open access: yes, 2019
MonografiaDue to periodic droughts the northeastern region of Brazil suffers from problems related to water scarcity, in this way, actions are needed to reduce the impacts caused by scarcity.
Geraldo, Victor Lima
core  

Trabalho (no) Feminino (1850-1926) : Histórias dos Açores

open access: yes, 2021
Neste número, a rubrica Agora dá notícia do webinar de apresentação pública dos resultados do Projeto Açores, retratos e tendências sociais, que estuda os principais indicadores estatísticos da sociedade e economia açorianas, e a rubrica Ágora partilha ...
Gil, Ana Cristina Correia, dir.   +1 more
core  

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

Ensaio de caracterização biofísica dos cursos de água da ilha de Santa Maria através da aplicação do River Habitat Survey

open access: yes, 2010
XIV Expedição Científica do Departamento de Biologia - Santa Maria 2009.O River Habitat Survey (RHS) foi desenvolvido pela Environment Agency britânica como metodologia de avaliação morfológica dos rios (RAVEN et al., 1998), tendo em vista a obtenção de ...
Medeiros, Carlos, Gonçalves, Vitor
core  

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

open access: yesFEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes   +4 more
wiley   +1 more source

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