Results 171 to 180 of about 710,282 (258)

Population-Based Health Survey in the municipality of São Paulo 2024: methodological and operational aspects. [PDF]

Rev Bras Epidemiol
Cesar CLG, Bassichetto KC, Silva ZPD, Louvison MCP, Fisberg RM, Alves MCGP, Escuder MML, Alencar GP, Bernal RTI, Santos EFS, Luiz ODC, Goldbaum M.   +11 more
europepmc   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Intraoperative gastroesophageal reflux in dogs undergoing mastectomy under opioid-based protocols: a preliminary endoscopic study. [PDF]

Vet Res Commun
Dos Santos Ribas P, Gurgel HJ, Alves Dos Santos GM, da Silva VS, de Oliveira Monteiro FD, Domingues SFS, Thiesen RMC, Thiesen R, Teixeira PPM.   +8 more
europepmc   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

FEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura, Shin‐ichi Tate, Kyota Yasuda   +2 more
wiley   +1 more source

COMPARATIVE STUDY OF DISTAL RADIUS FRACTURE FIXATION WITH A VOLAR PLATE VERSUS KIRSCHNER WIRES. [PDF]

Acta Ortop Bras
de Oliveira KS, Chaves KCB, Gomes PA, Sayegh GKS, Mauad VAQ, Pinto FNZ, Alves RS, de Lima EP, Dos Santos PCV.   +8 more
europepmc   +1 more source

Diversity and complexity in neural organoids

FEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Aging impact on canine extracellular vesicles production, size, and miRNA content. [PDF]

Vet Res Commun
Marina CL, Greuel AM, Las-Casas LO, Lopes-Gomes E, Romero Ferrari SSA, Rodrigues ML, Dos Reis FCG, Bocca AL, Titze-de-Almeida SS, Resende FFB, de Sant'Ana FJF, Titze-de-Almeida R.   +11 more
europepmc   +1 more source

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

FEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz, Mihály Mérey, Rebeka Vásárhelyi, Ramóna Pék, Victor Imburchia, László Henn, Adrián Kószó, Nicholas D. Lakin, Ivan Ahel, Sébastien Huet, Ágnes Czibula, Gyula Timinszky   +11 more
wiley   +1 more source

Action on waiting list for Speech Therapy in the Unified Health System (SUS) in a medium-sized Brazilian municipality. [PDF]

Codas
Salles TMA, Santos MGPD, Moraes RG, Alpes MF, Ferreira-Vasques AT.   +4 more
europepmc   +1 more source