Results 91 to 100 of about 11,975,902 (386)

A Review of Emerging Technologies Enabling Improved Solid Oral Dosage Form Manufacturing and Processing.

Advanced Drug Delivery Reviews, 2021
Muhammad Sohail Arshad, Saman Zafar, Bushra Yousef, Yasmine Alyassin, Radeyah Ali, Ali Alasiri, Ming‐Wei Chang, Z. Ahmad, Amal Ali Elkordy, A. Faheem, K. Pitt   +10 more
semanticscholar   +1 more source

Modeling hepatic fibrosis in TP53 knockout iPSC‐derived human liver organoids

Molecular Oncology, EarlyView.
This study developed iPSC‐derived human liver organoids with TP53 gene knockout to model human liver fibrosis. These organoids showed elevated myofibroblast activation, early disease markers, and advanced fibrotic hallmarks. The use of profibrotic differentiation medium further amplified the fibrotic signature seen in the organoids.
Mustafa Karabicici, Soheil Akbari, Ceyda Caliskan, Canan Celiker, Ozden Oz, Leman Binokay, Gökhan Karakulah, Serif Senturk, Esra Erdal   +8 more
wiley   +1 more source

PYCR1 inhibition in bone marrow stromal cells enhances bortezomib sensitivity in multiple myeloma cells by altering their metabolism

Molecular Oncology, EarlyView.
This study investigated how PYCR1 inhibition in bone marrow stromal cells (BMSCs) indirectly affects multiple myeloma (MM) cell metabolism and viability. Culturing MM cells in conditioned medium from PYCR1‐silenced BMSCs impaired oxidative phosphorylation and increased sensitivity to bortezomib.
Inge Oudaert, Lauren van den Broecke, Osman Aksoy, Judith Lind, Sonia Vallet, Arne Van der Vreken, Gamze Ates, Ann Massie, Ken Maes, Kim De Veirman, Elke De Bruyne, Karin Vanderkerken, Klaus Podar, Eline Menu   +13 more
wiley   +1 more source

Evaluasi Penggunaan Sediaan Farmasi Intravena Untuk Penyakit Infeksi Pada Salah Satu Rumah Sakit Swasta Di Kota Bandung [PDF]

, 2008
An USAge evaluation of intravenous pharmaceutical dosage form for infectious dis-eases at one of the private hospitals in Bandung by retrospective method on October to December 2005 had been done based on the rationality of drug used according to the ...
Kardinah, E. I. (Endah), Mandalas, E. (Esther), Surahman, E. (Emma)   +2 more
core  

In vitro properties of patient serum predict clinical outcome after high dose rate brachytherapy of hepatocellular carcinoma

Molecular Oncology, EarlyView.
Following high dose rate brachytherapy (HDR‐BT) for hepatocellular carcinoma (HCC), patients were classified as responders and nonresponders. Post‐therapy serum induced increased BrdU incorporation and Cyclin E expression of Huh7 and HepG2 cells in nonresponders, but decreased levels in responders.
Lukas Salvermoser, Jan Niklas Schäfer, Shraga Nahum Goldberg, Philipp Maximilian Kazmierczak, Moritz Nikolaus Gröper, Philipp Franz Linden, Elif Öcal, Tanja Burkard, Stefanie Corradini, Najib Ben Khaled, Moritz Wildgruber, Max Seidensticker, Jens Ricke, Matthias Stechele, Marianna Alunni‐Fabbroni   +14 more
wiley   +1 more source

Intranasal scopolamine preparation and method [PDF]

A new method and preparation for intranasal delivery of scopolamine provides a safe and effective treatment for motion sickness and other conditions requiring anticholinergic therapy. The preparation can be in the form of aqueous nasal drops, mist spray,
Cintron, Nitza M., Putcha, Lakshmi
core   +1 more source

Dosimeter for high levels of absorbed radiation Patent [PDF]

, 1969
Development of dosimeter for measuring absorbed dose of high energy ionizing ...
Bell, V. L., Jr., Pezdirtz, G. F.
core   +1 more source

Applications of Machine Learning in Solid Oral Dosage Form Development.

Journal of Pharmacy and Science, 2021
H. Lou, Bo Lian, M. Hageman
semanticscholar   +1 more source

Inhibition of CDK9 enhances AML cell death induced by combined venetoclax and azacitidine

Molecular Oncology, EarlyView.
The CDK9 inhibitor AZD4573 downregulates c‐MYC and MCL‐1 to induce death of cytarabine (AraC)‐resistant AML cells. This enhances VEN + AZA‐induced cell death significantly more than any combination of two of the three drugs in AraC‐resistant AML cells.
Shuangshuang Wu, Jianlei Zhao, Aaban Asfar Azmi, Avanti Gupte, Jenna Thibodeau, Shuang Liu, Jinli Yang, Guan Wang, Holly Edwards, Lisa A. Polin, Juiwanna Kushner, Sijana H. Dzinic, Kathryn White, Julie Boerner, Maik Hüttemann, Jay Yang, Yue Wang, Jeffrey W. Taub, Yubin Ge   +18 more
wiley   +1 more source

Ayurvedic Dosage Forms: Pressing Priorities and Challenges therein with Respect to Solid and Semisolid Oral Dosage Forms

Indian Journal of Ayurveda and Integrative Medicine KLEU
Continuous improvements in elevating traditional dosage forms to increase therapeutic efficacy, to enable patient-centric approaches, and to improve patient compliance are becoming more rational with advancements in technology and an advanced vision to ...
Sakshi Badyal, Poonam Dang, Puneet Dhawan, Himanshu Shekhar Tiwari   +3 more
doaj   +1 more source