Results 111 to 120 of about 11,911,230 (418)
Fast convergence rates for dose-response estimation [PDF]
We consider the problem of estimating a dose-response curve, both globally and locally at a point. Continuous treatments arise often in practice, e.g. in the form of time spent on an operation, distance traveled to a location or dosage of a drug. Letting A denote a continuous treatment variable, the target of inference is the expected outcome if ...
arxiv
Ibuprofen salt production and its application in tablet dosage form [PDF]
Ibuprofen is an anti-inflammatory drug and is practically insoluble in water. The low melting point and the poor flowability of ibuprofen can lead to process difficulty in tablets production.
Fudholi, Achmad+2 more
core +3 more sources
Patient‐derived xenografts (PDXs) can be improved by implantation of a humanized niche. We tested different biomaterials and approaches, and demonstrate that the combination of an injectable biomaterial for scaffold creation plus an intravenous route for acute myeloid leukemia (AML) xenotransplantation provide the most convenient and robust approach to
Daniel Busa+13 more
wiley +1 more source
Abstract Purpose Treatment planning for head‐and‐neck (H&N) cancer, in particular oropharynx, nasopharynx, and paranasal sinus cases, at our center requires noncoplanar proton beams due to the complexity of the anatomy and target location. Targeting accuracy for all beams is carefully evaluated by using image guidance before delivering proton beam ...
Nrusingh C. Biswal+5 more
wiley +1 more source
Study of vinpocetine intranasal dosage form consistence properties
Aim. Study of structural-mechanical nasal semisolid dosage forms on emulsion bases providing with optimal release active substance was done. Methods and results.
N. A. Nagornaya+2 more
doaj +1 more source
PULSATILE DRUG DELIVERY SYSTEM: AN "USER-FRIENDLY" DOSAGE FORM [PDF]
In the body under physiological conditions, many vital functions are regulated by transient release of bioactive substances at a specific time and site.
SHIVPRASAD H. MAJUMDAR, JIGAR D. PATEL, KRITIKA ANEJA,
core +1 more source
KMT2A degradation is observed in decitabine‐responsive acute lymphoblastic leukemia cells
We demonstrate that decitabine (DEC) not only degrades the DNA methyltransferase DNMT1 but also the leukemic driver lysine methyltransferase KMT2A likely due to structural similarity of the DNA‐binding CXXC domains. DEC influences KMT2A downstream processes and synergizes with menin inhibitor revumenib (REV) to decrease leukemic cell proliferation, and
Luisa Brock+10 more
wiley +1 more source
Image quality improvement in low‐dose chest CT with deep learning image reconstruction
Abstract Objectives To investigate the clinical utility of deep learning image reconstruction (DLIR) for improving image quality in low‐dose chest CT in comparison with 40% adaptive statistical iterative reconstruction‐Veo (ASiR‐V40%) algorithm. Methods This retrospective study included 86 patients who underwent low‐dose CT for lung cancer screening ...
Qian Tian+7 more
wiley +1 more source
The effectiveness of Okra gum in sustaining the release of propranolol hydrochloride in a tablet was studied. Okra gum was extracted from the pods of Hibiscus esculentus using acetone as a drying agent.
Nurul Dhania Zaharuddin+2 more
semanticscholar +1 more source