Results 121 to 130 of about 11,975,902 (386)
, 2013 A simple, rapid, precise and highly selective spectrophotometric method was developed for simultaneous estimation of Hesperidin and Diosmin in tablet dosage form.
Doddi Srilatha +4 more
semanticscholar +1 more source
Cytoplasmic p21 promotes stemness of colon cancer cells via activation of the NFκB pathway
Molecular Oncology, EarlyView.Cytoplasmic p21 promotes colorectal cancer stem cell (CSC) features by destabilizing the NFκB–IκB complex, activating NFκB signaling, and upregulating BCL‐xL and COX2. In contrast to nuclear p21, cytoplasmic p21 enhances spheroid formation and stemness transcription factor CD133.
Arnatchai Maiuthed +10 more
wiley +1 more source
SUPPOSITORIES: ASPECTS OF DOSAGE FORM MODERNIZATION
Разработка и регистрация лекарственных средств, 2019 In this material were reviewed biopharmaceutical aspects of suppositories – described the relation between rectal route of administration, bioaccessibility and principles of dosage forms formulation.
N. B. Diomina, M. N. Anurova
doaj
Acta Pharmaceutica, 2014 High performance liquid chromatography (HPLC) and second-order derivative spectrophotometry have been used for simultaneous determination of pravastatin (PS) and fenofibrate (FF) in pharmaceutical formulations.
Hefnawy Mohamed M. +4 more
doaj +1 more source
Study of vinpocetine intranasal dosage form consistence properties
Zaporožskij Medicinskij Žurnal, 2014 Aim. Study of structural-mechanical nasal semisolid dosage forms on emulsion bases providing with optimal release active substance was done. Methods and results.
N. A. Nagornaya +2 more
doaj +1 more source
, 2013 The objective of this paper is to develope a simple, precise, accurate, and reproducible reversed phase high performance liquid chromatographic method for the quantitative determination of chlorpheniramine maleate, ibuprofen, and phenylephrine ...
Pinak Sanchaniya +2 more
semanticscholar +1 more source
Molecular Oncology, EarlyView.HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto +13 more
wiley +1 more source
Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells
Molecular Oncology, EarlyView.Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son +13 more
wiley +1 more source
Strategy of Nannochloropsis Against Environment Starvation: Population Density and Crude Lipid Contents [PDF]
, 2013 Nannochloropsis sp., an unicellular marine microalgae, has potential function as a food source for fish larvae and in chemical industry. Microenvironmental conditions, especially nitrogen and salinity stress in marine ecosystems, became major factor ...
Hudaidah, S. (Siti) +2 more
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