Results 21 to 30 of about 653,512 (354)
Recent Advances in Studying Interfacial Adsorption of Bioengineered Monoclonal Antibodies
Monoclonal antibodies (mAbs) are an important class of biotherapeutics; as of 2020, dozens are commercialized medicines, over a hundred are in clinical trials, and many more are in preclinical developmental stages.
Peter Hollowell+6 more
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Simultaneous determination of the tandem of drugs, like meldonium and metoprolol, with enormous polarity differences between them, requires thorough research and careful selection of chromatographic conditions.
Marjan Piponski+8 more
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Adverse immunological responses against non-viral nanoparticle (NP) delivery systems in the lung
There is a large, unmet medical need to treat chronic obstructive pulmonary disease, asthma, idiopathic pulmonary fibrosis and other respiratory diseases.
Leonor de Braganca+3 more
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Development of Mucoadhesive Gel Microbicide to Target Mucosal HIV Reservoirs [PDF]
The wide use of microbicide is mainly depends on its effectiveness, less frequent application, ready availability and most importantly cost. The aim of this work was to develop affordable microbicide mucoadhesive gel formulation of synthetic anti HIV ...
Shegokar, Ranjita, Singh, Kamalinder K
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Despite ongoing international efforts, many drugs administered to children must be compounded from dosage forms designed for adults because they remain unavailable in commercial formulations that suit their needs.
Émilie Kate Landry+6 more
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The knowledge, attitudes and beliefs of patients and their healthcare professionals around oral dosage form modification: a systematic review of the qualitative literature [PDF]
Objectives: The objective of this systematic review was to synthesize the available qualitative evidence on the knowledge, attitudes and beliefs of adult patients, healthcare professionals and carers about oral dosage form modification.
Crean, Abina M.+3 more
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MELATONIN DOSAGE FORMS WITH AN EMPHASIS ON MODIFIED RELEASE DOSAGE FORMS
The first objective of this study was to evaluate melatonin properties related with the release behavior of this substance in oral controlled release tablets. Melatonin was found as a highly soluble substance with a micronized particle size (D50=4.1µm) and recrystallization in the same polymorphic form.
openaire +1 more source
Continuous powder feeding for pharmaceutical solid dosage form manufacture: a short review [PDF]
There has been a noticeable shift from pharmaceutical batch processing towards a more continuous mode of manufacture for solid oral dosage forms. Continuous solid oral dose processes would not be possible in the absence of a highly accurate feeding ...
Blackshields, Caroline A.+1 more
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Chipping away at gamma-H2AX foci [PDF]
The mammalian histone H2AX protein functions as a dosage-dependent genomic caretaker and tumor suppressor. Phosphorylation of H2AX to form gamma-H2AX in chromatin around DNA double strand breaks (DSBs) is an early event following induction of these ...
Bassing, Craig H+3 more
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Polygala japonica Houtt. (PJ), a member of the Polygala L. family that is suggested to exhibit detoxification properties in traditional Chinese medicine, is often used to treat upper respiratory tract infections.
Yinan Wu+7 more
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