Results 21 to 30 of about 11,975,902 (386)

Development of Mucoadhesive Gel Microbicide to Target Mucosal HIV Reservoirs [PDF]

open access: yes, 2014
The wide use of microbicide is mainly depends on its effectiveness, less frequent application, ready availability and most importantly cost. The aim of this work was to develop affordable microbicide mucoadhesive gel formulation of synthetic anti HIV ...
Shegokar, Ranjita, Singh, Kamalinder K
core   +1 more source

A Multiple Unit Abuse-deterrent Dosage Form Based on Sodium Alginate

open access: yesEuropean Pharmaceutical Journal, 2023
There are several approaches for the formulation of abuse-deterrent, tamper-resistant, or alcohol-resistant dosage forms. This work is specifically focused on the formulation of microforms and multiple unit dosage forms with the mentioned resistant ...
Papadakos M.   +3 more
doaj   +1 more source

Design of targeted dosage form of ofloxacin+ [PDF]

open access: yesJournal of the Serbian Chemical Society, 2006
The targeted pro-drug is a classical pro-drug design often representing a non-specific chemical approach to mask undesirable drug properties, such as limited bioavailability, lack of site specificity, and chemical instability. On the other hand, targeted
Shahar Yar M.   +3 more
doaj   +3 more sources

Measuring aggregates, self-association, and weak interactions in concentrated therapeutic antibody solutions

open access: yesmAbs, 2020
Monoclonal antibodies are a class of biotherapeutics used for an increasing variety of disorders, including cancer, autoimmune, neurodegenerative, and viral diseases.
Sumit K. Chaturvedi   +8 more
doaj   +1 more source

Embedded 3D Printing of Novel Bespoke Soft Dosage Form Concept for Pediatrics

open access: yesPharmaceutics, 2019
Embedded three-dimensional printing (e-3DP) is an emerging method for additive manufacturing where semi-solid materials are extruded within a solidifying liquid matrix. Here, we present the first example of employing e-3DP in the pharmaceutical field and
Katarzyna Rycerz   +7 more
semanticscholar   +1 more source

Recent Advances in Studying Interfacial Adsorption of Bioengineered Monoclonal Antibodies

open access: yesMolecules, 2020
Monoclonal antibodies (mAbs) are an important class of biotherapeutics; as of 2020, dozens are commercialized medicines, over a hundred are in clinical trials, and many more are in preclinical developmental stages.
Peter Hollowell   +6 more
doaj   +1 more source

Concepts for a New Rapid and Simple HPLC Method for Simultaneous Determination of Metoprolol and Meldonium in Pharmaceutical Dosage Forms

open access: yesScientia Pharmaceutica, 2022
Simultaneous determination of the tandem of drugs, like meldonium and metoprolol, with enormous polarity differences between them, requires thorough research and careful selection of chromatographic conditions.
Marjan Piponski   +8 more
doaj   +1 more source

Advances in oral transmucosal drug delivery [PDF]

open access: yes, 2011
Original article can be found at : http://sciencedirect.com/ Copyright ElsevierThe successful delivery of drugs across the oral mucosa represents a continuing challenge, as well as a great opportunity.
Brown, Marc   +2 more
core   +1 more source

Liqui-Pellet: the Emerging Next-Generation Oral Dosage Form Which Stems from Liquisolid Concept in Combination with Pelletization Technology

open access: yesAAPS PharmSciTech, 2019
In spite of the major advantages that the liquisolid technology offers, particularly in tackling poor bioavailability of poorly water-soluble drugs (i.e., BCS Class II drugs), there are a few critical drawbacks. The inability of a high liquid load factor,
Matthew Lam, T. Ghafourian, A. Nokhodchi
semanticscholar   +1 more source

Tapentadol extended release for the management of chronic neck pain [PDF]

open access: yes, 2017
BACKGROUND: The role of opioids in the management of chronic neck pain is still poorly investigated. No data are available on tapentadol extended release (ER).
Coluzzi, Flaminia
core   +1 more source

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