Results 21 to 30 of about 11,719,375 (360)

Liqui-Pellet: the Emerging Next-Generation Oral Dosage Form Which Stems from Liquisolid Concept in Combination with Pelletization Technology

AAPS PharmSciTech, 2019
In spite of the major advantages that the liquisolid technology offers, particularly in tackling poor bioavailability of poorly water-soluble drugs (i.e., BCS Class II drugs), there are a few critical drawbacks. The inability of a high liquid load factor,
Matthew Lam, T. Ghafourian, A. Nokhodchi
semanticscholar   +1 more source

Recent Advances in Studying Interfacial Adsorption of Bioengineered Monoclonal Antibodies

Molecules, 2020
Monoclonal antibodies (mAbs) are an important class of biotherapeutics; as of 2020, dozens are commercialized medicines, over a hundred are in clinical trials, and many more are in preclinical developmental stages.
Peter Hollowell, Zongyi Li, Xuzhi Hu, Sean Ruane, Cavan Kalonia, Christopher F. van der Walle, Jian R. Lu   +6 more
doaj   +1 more source

Concepts for a New Rapid and Simple HPLC Method for Simultaneous Determination of Metoprolol and Meldonium in Pharmaceutical Dosage Forms

Scientia Pharmaceutica, 2022
Simultaneous determination of the tandem of drugs, like meldonium and metoprolol, with enormous polarity differences between them, requires thorough research and careful selection of chromatographic conditions.
Marjan Piponski, Mariana Horyn, Kristina Grncaroska, Oleksandra Oleshchuk, Elena Petrovska, Stefan Angelevski, Tetyana Uglyar, Tetyana Kucher, Liliya Logoyda   +8 more
doaj   +1 more source

Adverse immunological responses against non-viral nanoparticle (NP) delivery systems in the lung

Journal of Immunotoxicology, 2021
There is a large, unmet medical need to treat chronic obstructive pulmonary disease, asthma, idiopathic pulmonary fibrosis and other respiratory diseases.
Leonor de Braganca, G. John Ferguson, Jose Luis Santos, Jeremy P. Derrick   +3 more
doaj   +1 more source

Drug Prescriptions Requiring Compounding at a Canadian University Affiliated Pediatric Hospital: A Cross-Sectional Study

Children, 2023
Despite ongoing international efforts, many drugs administered to children must be compounded from dosage forms designed for adults because they remain unavailable in commercial formulations that suit their needs.
Émilie Kate Landry, Julie Autmizguine, Sophie Bérubé, Raphael Kraus, Marie-Élaine Métras, Denis Lebel, Catherine Litalien   +6 more
doaj   +1 more source

Changing the pill: developments toward the promise of an ultra-long-acting gastroretentive dosage form

Expert Opinion on Drug Delivery, 2018
Introduction: The development of oral sustained release dosage forms has been a longstanding goal due to the potential for ease of administration, improved pharmacokinetics, reduced dosing frequency, and improved adherence.
David H. Altreuter, Ameya R. Kirtane, Tyler M. Grant, Cecilia Kruger, G. Traverso, Andrew M Bellinger   +5 more
semanticscholar   +1 more source

Application of Fourier transform infrared (FTIR) spectroscopy coupled with multivariate calibration for quantitative analysis of curcuminoid in tablet dosage form

Journal of Applied Pharmaceutical Sciences, 2018
© 2018 Chairany Siregar et al. This is an open access article distributed under the terms of the Creative Commons Attribution License -NonCommercial-ShareAlikeUnported License (http://creativecommons.org/licenses/by-nc-sa/3.0/).
C. Siregar, S. Martono, A. Rohman
semanticscholar   +1 more source

Enhanced rational protein engineering to reduce viscosity in high-concentration IgG1 antibody solutions

mAbs
Subcutaneous (SC) delivery of therapeutic antibodies can offer multiple benefits to patients and healthcare providers, including convenience, time savings, and cost reduction.
Tyler J. Lefevre, Jenna G. Caldwell, Austin Gallegos, Qun Du, Erin Houston, Gilad Kaplan, Reza Esfandiary   +6 more
doaj   +1 more source

A REVIEW ON CIPROFLOXACIN: DOSAGE FORM PERSPECTIVE

International Journal of Applied Pharmaceutics, 2018
Ciprofloxacin (CF) is one of the topmost selling antibiotics and it is available at a cheap cost which is used to treat many bacterial infections. Many research scientists are working on this drug for various applications on different drug delivery ...
M. Vidyavathi, G. Srividya
semanticscholar   +1 more source

Assessing subvisible particle risks in monoclonal antibodies: insights from quartz crystal microbalance with dissipation, machine learning, and in silico analysis

mAbs
Throughout the lifecycle of biopharmaceutical development and manufacturing, monoclonal antibodies (mAbs) are subjected to diverse interfacial stresses and encounter various container surfaces.
Yibo Wang, Alexis Hanford, Mehdi Boroumand, Cavan Kalonia, Jesse Leissa, Mitali Shah, Tony Pham, Theodore Randolph, Indira Prajapati   +8 more
doaj   +1 more source