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Evaluation of Dosage Forms. VI. Studies of Commercial Oxyphenbutazone Tablet Dosage Forms

Drug Development and Industrial Pharmacy, 1999
Dissolution-dialysis studies of commercial tablets of oxyphenbutazone were carried out to establish the applicability of this technique for the in vitro evaluation of oxyphenbutazone dosage form. While disintegration time and dissolution rate studies did not give a true indication of bioavailability, an excellent correlation was obtained between the ...
Balkishen Razdan, N. V. Nagaraj
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Evaluation of Dosage Forms. IV. Studies on Commercial Phenylbutazone Tablet Dosage Forms

Drug Development and Industrial Pharmacy, 1998
In order to determine the feasibility of dissolution-dialysis as a suitable technique for in vitro evaluation, studies on commercial phenylbutazone tablets were carried out. Although disintegration time and dissolution parameters did not give a true indication of bioavailability, an excellent correlation was obtained between the dialysis rate constant (
Balkishen Razdan, Anant Paradkar
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Electrospinning and its potential in fabricating pharmaceutical dosage form

Journal of Drug Delivery Science and Technology, 2022
Siew Mei Tan   +7 more
semanticscholar   +1 more source

Pharmaceutical application and development of fixed-dose combination: dosage form review

Journal of Pharmaceutical Investigation, 2021
Dong-Wook Kim, Kwon-Yeon Weon
semanticscholar   +1 more source

Effect of surfactants, gastric emptying, and dosage form on supersaturation of dipyridamole in an in vitro model simulating the stomach and duodenum.

Molecular Pharmaceutics, 2014
The purpose of this study was to investigate the influence of gastric emptying patterns, surfactants, and dosage form on the supersaturation of a poorly soluble weakly basic drug, dipyridamole, using an in vitro model mimicking the dynamic environment of
A. Mitra, H. Fadda
semanticscholar   +1 more source

Pharmaceutical Dosage Forms

1979
Pharmaceutical aerosols are packaged under pressure and contain therapeutically active ingredients. They are intended for topical application to the skin as well as local application, including inhalation.
W. T. Lowry, James C. Garriott
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Assessment of Dosage Forms In Vitro

1988
This chapter presents descriptions of some in vitro tests which can be applied to pharmaceutical products, using some of the background physical chemistry discussed in other chapters. In particular, we will examine the influence of some of the key parameters of pharmaceutical systems, such as particle size, viscosity, adhesion or formulation in general
D. Attwood, A. T. Florence
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Disintegrants in Solid Dosage Forms

Drug Development and Industrial Pharmacy, 1990
AbstractThe dynamic approach to tablet disintegration, which is based on the measurement of the force that develops inside the compact upon water entrance, is basically taken up.The combined measurements of force development and water uptake, simultaneously effected on the same compact, provide a novel parameter that is proposed to quantify and compare
CARAMELLA, CARLA MARCELLA   +3 more
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Formulation of Dosage Forms

1996
All drugs are administered to the body in some type of dosage form that consists of the active ingredient plus other inactive components, commonly known as excipients. The objective of the pharmaceutical formulator is to prepare a convenient-to-administer, aesthetically acceptable dosage form that presents an accurate and precise amount of a physically
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Dosage Forms of Digitoxin

Annals of Internal Medicine, 1970
Excerpt To the editor: In their article entitled "An Improved Method of Digitoxin Therapy" (Ann Intern Med72: 453-464, 1970), Jelliffe and co-workers stated under Dosage Forms of Digitoxin (p.
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