Results 71 to 80 of about 11,719,375 (360)

High-performance liquid chromatography and derivative spectrophotometry for simultaneous determination of pravastatin and fenofibrate in the dosage form

Acta Pharmaceutica, 2014
High performance liquid chromatography (HPLC) and second-order derivative spectrophotometry have been used for simultaneous determination of pravastatin (PS) and fenofibrate (FF) in pharmaceutical formulations.
Hefnawy Mohamed M., Mohamed Mostafa S., Abounassif Mohammed A., Alanazi Amer M., Mostafa Gamal A. E.   +4 more
doaj   +1 more source

Real‐time assay of ribonucleotide reductase activity with a fluorescent RNA aptamer

FEBS Letters, EarlyView.
Ribonucleotide reductases (RNR) synthesize DNA building blocks de novo, making them crucial in DNA replication and drug targeting. FLARE introduces the first single‐tube real‐time coupled RNR assay, which enables isothermal tracking of RNR activity at nanomolar enzyme levels and allows the reconstruction of allosteric regulatory patterns and rapid ...
Jacopo De Capitani, Noemi E. Nwosu, Viktoria Gocke, Müge Kasanmascheff, Hannes Mutschler   +4 more
wiley   +1 more source

Tablet for Vaginal Solution Dosage Form [PDF]

, 2020
National Cancer Institute
openalex   +1 more source

The role of histone modifications in transcription regulation upon DNA damage

FEBS Letters, EarlyView.
This review discusses the critical role of histone modifications in regulating gene expression during the DNA damage response (DDR). By modulating chromatin structure and recruiting repair factors, these post‐translational modifications fine‐tune transcriptional programmes to maintain genomic stability.
Angelina Job Kolady, Siyao Wang
wiley   +1 more source

The Use of Plant-Derived Biomaterials as Drug Formulation Excipients: An Application of Biomimetics in Dosage Form Development

Proceedings
To develop an active drug into a suitable dosage form, pharmaceutical scientists combine various excipients (additives) obtained from different sources [...]
Omobolanle Ayoyinka Omoteso, Yusuf Oluwagbenga Ghazali, Michael Ayodele Odeniyi   +2 more
doaj   +1 more source

Development of the Tablet Dosage Form Composition for the Inductor of Hepatocytes Monooxygenase System Based on 6,8-dimethyl-2-piperidinomethyl-2,3-dihydrothiazolo[2,3-F]xanthine

, 2023
AV Petrakov, Vladimir V. Sheikin, С. В. Кривощеков, Ekaterina Bezverkhniaia, A. M. Guryev, М. В. Белоусов   +5 more
openalex   +2 more sources

Intraocular Instillation Solution Dosage Form [PDF]

, 2020
National Cancer Institute
openalex   +1 more source

Liquid Hydroxyurea (Xromi) for Children With Sickle Cell Anemia: A New Solution Compounding Existing Problems

Pediatric Blood &Cancer, EarlyView.
Alexandra Power‐Hays, Charles T. Quinn
wiley   +1 more source

Function‐driven design of a surrogate interleukin‐2 receptor ligand

FEBS Letters, EarlyView.
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang, Zelin Cheng, Teng Li, Fulian Wang, Liangminghui Zhang, Xiuxiu He, Lili Liu, Wei Wang, Aibin Liang, Guang Yang   +9 more
wiley   +1 more source

The Use of Hibiscus esculentus (Okra) Gum in Sustaining the Release of Propranolol Hydrochloride in a Solid Oral Dosage Form

BioMed Research International, 2014
The effectiveness of Okra gum in sustaining the release of propranolol hydrochloride in a tablet was studied. Okra gum was extracted from the pods of Hibiscus esculentus using acetone as a drying agent.
Nurul Dhania Zaharuddin, M. I. Noordin, A. Kadivar   +2 more
semanticscholar   +1 more source