Results 71 to 80 of about 11,911,230 (418)

Gel - A new drug dosage form for Ayurved medicines [PDF]

open access: yes, 2017
Rasashastra and Bhaishajya Kalpana is the science dealing with processing of Ayurved medicines. Due to globalisation of Ayurved science it is need of time to convert our dosage form into palatable and convenient form towards the patient without ...
Dr. Neky Mehta
core   +3 more sources

Unconventional mRNA processing and degradation pathways for the polycistronic yrzI (spyTA) mRNA in Bacillus subtilis

open access: yesFEBS Letters, EarlyView.
The S1025 peptide is the major antidote to the YrzI toxin, which we renamed here as SpyT (Small Peptide YrzI Toxin) and SpyA (Small Peptide YrzI Antitoxin) (1). Degradation of the toxin–antitoxin spyTA mRNA, either by a translation‐dependent cleavage by the endoribonuclease Rae1 (2) or by direct attack by 3′‐exoribonucleases (3), also contributes to ...
Laetitia Gilet   +4 more
wiley   +1 more source

Extracting Daily Dosage from Medication Instructions in EHRs: An Automated Approach and Lessons Learned [PDF]

open access: yesarXiv, 2020
Medication timelines have been shown to be effective in helping physicians visualize complex patient medication information. A key feature in many such designs is a longitudinal representation of a medication's daily dosage and its changes over time. However, daily dosage as a discrete value is generally not provided and needs to be derived from free ...
arxiv  

Quantification of Captopril using Ultra High Performance Liquid Chromatography [PDF]

open access: yesarXiv, 2021
We develop an efficient, sensitive, accurate, cost effective, and greener liquid chromatography method for the determination of a quantification method concerning Captopril in pharmaceutical dosage forms by using ultra high performance liquid chromatography (UHPLC) equipment.
arxiv  

Solid oral dosage form manufacturing using injection moulding [PDF]

open access: yes, 2017
The most preferred route of drug administration is via an oral dosage form and currently the most widely used manufacturing method is direct compression of powder blends. However it can be difficult to control the homogeneity of these dosage forms due to
Florence, Alastair   +2 more
core   +1 more source

Refining the NaV1.7 pharmacophore of a class of venom‐derived peptide inhibitors via a combination of in silico screening and rational engineering

open access: yesFEBS Letters, EarlyView.
Venom peptides have shown promise in treating pain. Our study uses computer screening to identify a peptide that targets a sodium channel (NaV1.7) linked to chronic pain. We produced the peptide in the laboratory and refined its design, advancing the search for innovative pain therapies.
Gagan Sharma   +8 more
wiley   +1 more source

Biopharmaceutical properties of polyvalent bacteriophage capsules

open access: yesБиопрепараты: Профилактика, диагностика, лечение, 2023
Scientific relevance. Rational phage therapy is a highly effective way to combat bacterial infections, especially in conditions of steadily increasing antibiotic resistance.
A. M. Nikolaeva   +4 more
doaj   +1 more source

DEVELOPMENT AND STABILITY INDICATING HPLC METHOD FOR DAPAGLIFLOZIN IN API AND PHARMACEUTICAL DOSAGE FORM

open access: yes, 2017
Objective: To develop precise, accurate and reproducible stability assay method by RP-HPLC for estimation of dapagliflozin in API and pharmaceutical dosage form. Methods: The adequate separation was carried using agilent C18 (4.6 ml (millimeter)*150,5 µm
Mitali V. Verma   +2 more
semanticscholar   +1 more source

Identification of novel small molecule inhibitors of ETS transcription factors

open access: yesFEBS Letters, EarlyView.
ETS transcription factors play an essential role in tumourigenesis and are indispensable for sprouting angiogenesis, a hallmark of cancer, which fuels tumour expansion and dissemination. Thus, targeting ETS transcription factor function could represent an effective, multifaceted strategy to block tumour growth. The evolutionarily conserved E‐Twenty‐Six
Shaima Abdalla   +9 more
wiley   +1 more source

Feasibility of Material Decomposition-based Photon-counting CT Thermometry [PDF]

open access: yesarXiv, 2022
Over the past decades, thermal ablation procedures such as high intensity focused ultrasound (HIFU) have been developed vaporize cancerous tissues in a focal area. Thermal ablation has the potential to non-invasively eliminate tumors and treat other medical conditions with high efficacy and better patient outcomes.
arxiv  

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