Results 11 to 20 of about 191,476 (314)

A study on blocking store-operated Ca2+ entry in pulmonary arterial smooth muscle cells with xyloketals from marine fungi

open access: yesActa Pharmaceutica, 2017
In this study, the effect of four xyloketals 1-4 on store-operated calcium entry (SOCE) was investigated in primary distal pulmonary arterial smooth muscle cells (PASMCs) isolated from mice.
Zhou Jie-Bin   +5 more
doaj   +1 more source

The characteristics of novel dosage forms [PDF]

open access: yesHemijska Industrija, 2003
The objective of pharmaceutical-technological development is to find a procedure of transforming an active substance (a drug) into a drug dosage form which is not only acceptable for application, but also enables the active substance to be released ...
Milić-Aškrabić Jela   +1 more
doaj   +1 more source

The use of machine learning methods in the development of nasal dosage forms with cerebroprotective action

open access: yesAktualʹnì Pitannâ Farmacevtičnoï ì Medičnoï Nauki ta Praktiki, 2021
In order to save resource of active pharmaceutical ingredients and excipients, in the early stages of research, when planning an experiment, it is advisable to use data of the predicted and experimental physicochemical properties stored in different ...
B. S. Burlaka, I. F. Bielenichev
doaj   +1 more source

Novel pharmaceutical dosage forms of analgesics [PDF]

open access: yesArhiv za farmaciju, 2018
Among novel pharmaceutical dosage forms of analgesics, whose number and diversity are continuously increasing over the past two decades, of particular importance are transdermal opioid analgesics (fentanyl, buprenorphine) for the treatment of chronic ...
Đekić Ljiljana, Primorac Marija
doaj   +1 more source

MELATONIN DOSAGE FORMS WITH AN EMPHASIS ON MODIFIED RELEASE DOSAGE FORMS

open access: yes, 2022
The first objective of this study was to evaluate melatonin properties related with the release behavior of this substance in oral controlled release tablets. Melatonin was found as a highly soluble substance with a micronized particle size (D50=4.1µm) and recrystallization in the same polymorphic form.
openaire   +1 more source

Tobacco: Its Conventional and Modern Dosage Forms in Medication

open access: yesBezmiâlem Science, 2022
Tobacco is one of the most planted products in worldwide and the whole Nicotiana tabacum L. plant, its leaves, flowers, seeds or roots, and individual chemical compounds have medicinal uses such as as sedative, diuretic, or expectorant.
İmren ESENTÜRK-GÜZEL   +4 more
doaj   +1 more source

The research on creation the dosage form based on 3-(4-nitrophenyl)-5-(nonylsulfonyl)-1,2,4-triazol-4-amine

open access: yesZaporožskij Medicinskij Žurnal, 2014
The search of new biologically active substances, which can be potential drugs with low toxicity and high levels of biological effects, is one of the major aims of modern medicine and pharmacy. Chemical modification of heterocyclic molecules, such as 1,2,
M. A. Shcherbak   +3 more
doaj   +1 more source

Taste-Masked Pellets of Warfarin Sodium: Formulation towards the Dose Personalisation

open access: yesPharmaceutics
The bitter drug, warfarin, has a narrow therapeutic index (NTI) and is used in paediatrics and geriatrics. The aim of this feasibility study was to formulate the taste-masked warfarin-containing pellets to be applicable for dose personalisation and to ...
Lakija Kovalenko   +3 more
doaj   +1 more source

Progress in the development of mRNA vaccine and its delivery systems for anti-tumor immunotherapy [PDF]

open access: yesZhongguo aizheng zazhi
Due to the drawbacks of low specificity and high risk of side effects of traditional anti-tumor treatments in clinical practice, novel anti-tumor immunotherapy has received attention and has been gradually applied.
XIN Meiyi, LIN Yuhong, ZHAO Kai
doaj   +1 more source

The Effect of Microcrystalline Cellulose–CaHPO4 Mixtures in Different Volume Ratios on the Compaction and Structural–Mechanical Properties of Tablets

open access: yesPharmaceutics
Using microcrystalline cellulose (MCC) with plastic behaviour and calcium phosphate anhydrous (CaHPO4) with brittle behaviour under compaction is very popular in the pharmaceutical industry for achieving desirable structural–mechanical properties of ...
Valentyn Mohylyuk   +3 more
doaj   +1 more source

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