Results 21 to 30 of about 197,281 (266)

Development of the method for the pharmaceutical availability testing of clotrimazole from multiphase semi-solid vaginal dosage forms [PDF]

Farmacja Polska, 2023
Introduction: The intravaginal drug administration enables treatment of the local and systemic diseases. The anatomy and physiology of a vagina provide several difficulties for drug technologists due to the small amount and continuous production of ...
Michał Smoleński, Dorota Haznar-Garbacz, Susanne Florin-Muschert, Katarzyna Małolepsza-Jarmołowska   +3 more
doaj   +1 more source

Formulation and Characterization of Felodipine as an Oral Nanoemulsions

Iraqi Journal of Pharmaceutical Sciences, 2021
Felodipine is a calcium-channel blocker with low aqueous solubility and bioavailability. Lipid dosage forms are attractive delivery systems for such hydrophobic drug molecules.
Sumaya B. Hamed, Shaimaa N. Abd Alhammid
doaj   +1 more source

The use of machine learning methods in the development of nasal dosage forms with cerebroprotective action

Aktualʹnì Pitannâ Farmacevtičnoï ì Medičnoï Nauki ta Praktiki, 2021
In order to save resource of active pharmaceutical ingredients and excipients, in the early stages of research, when planning an experiment, it is advisable to use data of the predicted and experimental physicochemical properties stored in different ...
B. S. Burlaka, I. F. Bielenichev
doaj   +1 more source

Taste-Masked Pellets of Warfarin Sodium: Formulation towards the Dose Personalisation

Pharmaceutics
The bitter drug, warfarin, has a narrow therapeutic index (NTI) and is used in paediatrics and geriatrics. The aim of this feasibility study was to formulate the taste-masked warfarin-containing pellets to be applicable for dose personalisation and to ...
Lakija Kovalenko, Kirils Kukuls, Marta Berga, Valentyn Mohylyuk   +3 more
doaj   +1 more source

The Effect of Microcrystalline Cellulose–CaHPO₄ Mixtures in Different Volume Ratios on the Compaction and Structural–Mechanical Properties of Tablets

Pharmaceutics
Using microcrystalline cellulose (MCC) with plastic behaviour and calcium phosphate anhydrous (CaHPO4) with brittle behaviour under compaction is very popular in the pharmaceutical industry for achieving desirable structural–mechanical properties of ...
Valentyn Mohylyuk, Artūrs Paulausks, Oskars Radzins, Liga Lauberte   +3 more
doaj   +1 more source

The characteristics of novel dosage forms [PDF]

Hemijska Industrija, 2003
The objective of pharmaceutical-technological development is to find a procedure of transforming an active substance (a drug) into a drug dosage form which is not only acceptable for application, but also enables the active substance to be released ...
Milić-Aškrabić Jela, Petrović Slobodan D.   +1 more
doaj   +1 more source

Development of Orally Disintegrating Tablets of Standardized Rhodiola rosea Extract

Pharmaceuticals
Background/Objectives: Rhodiola rosea L. (Crassulaceae), a perennial adaptogenic herb native to Northern Europe, Asia, and North America, is renowned for its therapeutic properties attributed to phenolic compounds including flavonoids, phenylethanoids ...
Oxana Brante, Rihards Talivaldis Bagons, Santa Niedra, Austris Mazurs, Baiba Mauriņa, Jurga Bernatoniene, Konstantins Logviss   +6 more
doaj   +1 more source

Predicting Drug Loading Capacity for PLA-Amorphous Drug System Using Hansen Solubility Parameters

Pharmaceutics
Objective: In this work, we look at Hansen solubility parameters (HSPs) to predict drug miscibility with polymers, in order to create a saturated amorphous drug phase.
Artūrs Paulausks, Artjoms Iljičevs, Jurga Bernatoniene, Līga Pētersone, Konstantīns Logviss   +4 more
doaj   +1 more source

Genomic Diversity and Clinical Variability in Pediatric Primary Cutaneous Anaplastic Large Cell Lymphoma: A Case Series

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Primary cutaneous anaplastic large cell lymphoma (pcALCL) is a rare pediatric CD30‐positive T‐cell lymphoproliferative disorder with an excellent prognosis, but its genomic drivers are poorly defined. We report three children with skin‐limited disease demonstrating striking molecular heterogeneity, including NPM::ALK, NUP214::FRK, and a novel ...
Shoshana Greenberger, Efrat Bar‐Ilan, Victoria Marcu, Evgeny Grishin, Rinat Yacobi, Aviv Barzilai, Hana Golan, Assaf Arie Barg   +7 more
wiley   +1 more source

Antibacterial Activity of Novel Agent N-2-Hydroxypropyl Trimethyl Ammonium Chloride Chitosan against Streptococcus mutans

Molecules
Dental caries (DC) is one of the most common oral diseases and is mainly caused by Streptococcus mutans (S. mutans). The use of antibiotics against S. mutans usually has side effects, including developing resistance.
Yuan Gao, Xiaochen Gong, Qicheng Ruan, Chunjing Zhang, Kai Zhao   +4 more
doaj   +1 more source