Objective Mycophenolate Mofetil (MMF) use in limited cutaneous systemic sclerosis (lcSSc) is relatively uncommon due to the lower fibrotic burden and the predominance of the vascular complications. In vitro observations and clinical data from transplanted patients suggest a protective effect of MMF on endothelial function.
Enrico De Lorenzis +77 more
wiley +1 more source
Externally validated population pharmacokinetics of amikacin and evaluation of dosage regimen based on achieved serum concentrations in neonates. [PDF]
Lim CP +7 more
europepmc +1 more source
Application of Population Pharmacokinetic Modeling, Exposure-Response Analysis, and Classification and Regression Tree Analysis to Support Dosage Regimen and Therapeutic Drug Monitoring of Plazomicin in Complicated Urinary Tract Infection Patients with Renal Impairment. [PDF]
Zhuang L +5 more
europepmc +1 more source
Objective The objective of this study was to describe the longitudinal disease course and pulmonary outcomes of North American patients with melanoma differentiation‐associated gene 5 antibody (MDA5 ab) associated dermatomyositis (DM). Methods Thirty patients with MDA5 ab DM were identified in a single center longitudinal cohort of 352 patients with ...
Jenice X Cheah +8 more
wiley +1 more source
Model Based Approach for Estimating the Dosage Regimen of Indomethacin a Potential Antiviral Treatment of Patients Infected with SARS CoV-2 [PDF]
Gomeni R +3 more
europepmc +2 more sources
Dosage Regimen Optimization of Ertapenem Against ESBL-Producing Enterobacterales Infection in Critically Ill Patients Using Monte Carlo Simulation. [PDF]
Muangkasem A +4 more
europepmc +1 more source
Effects of Carbon Nanoparticles on Triboelectro‐Induced Surface Defects
Carbon nanoparticles added to grease modify the electrocontact behavior. The synergy of particle concentration and electric current dominates the surface damage of metals in contact. Electrical surface damage caused by current leakage is a critical challenge in high‐performance applications such as electric vehicle (EV) drivetrains and wind turbine ...
Mohsen Tajedini +6 more
wiley +1 more source
Evaluation of a New Sublingual Methylcobalamin Dosage Regimen for Childhood Vitamin B12 Deficiency. [PDF]
Aydin S, Islamoglu SC, Oz A.
europepmc +1 more source
Rheocasting versus Die Casting: An Insight into the Low‐Cycle Fatigue Behavior of AlSi7Mg0.6
The study compares rheocast lightweight components with high‐pressure die cast materials regarding microstructure and fatigue behavior. Rheocast process offers higher efficiency due to lower casting temperatures. Despite some microstructural differences, both processes show similar strengths (yield strength 125 MPa, tensile strength 240 MPa).
Julia Richter +4 more
wiley +1 more source
Feasibility study of very high aprotinin dosage in polytrauma patients [PDF]
Clasen, C. +4 more
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