Results 11 to 20 of about 188,637 (301)

ON THE SELECTION OF DRUGS DOSAGE REGIMEN

Рациональная фармакотерапия в кардиологии, 2015
A complex system of hemostasis regulation, insufficient data on drugs pharmacokinetics, multiple factors effecting treatment, including patient’s adherence to therapy, that can lead to the need for the dosage regimen specification are presented.
E. N. Bochanova
doaj   +3 more sources

Ultra-Low Dosage Regimen of Rituximab in Autoimmune Blistering Skin Conditions [PDF]

Frontiers in Immunology, 2018
Mauro Alaibac
doaj   +2 more sources

Melarsoprol cyclodextrin inclusion complexes as promising oral candidates for the treatment of human African trypanosomiasis [PDF]

, 2011
Human African trypanosomiasis (HAT), or sleeping sickness, results from infection with the protozoan parasites <i>Trypanosoma brucei</i> (<i>T.b.</i>) <i>gambiense</i> or <i>T.b.rhodesiense</i> and is ...
AA Poltera, Amy Jones, B Evrard, B Raz, Barbara Bradley, BJ Berger, C Burri, C Burri, CA Hunter, Christopher McCabe, E Torreele, EW Hurst, FIC Apted, FW Jennings, George Gettinby, H Hirumi, J Opigo, J Pepin, J Pepin, J Rodgers, J Rodgers, Jayne Raper, Jean Rodgers, JH Zar, JLM Atouguia, JW Wong, Michael P. Barrett, MP Barrett, MP Barrett, NJ Abbott, Peter G. E. Kennedy, PGE Kennedy, PGE Kennedy, PGE Kennedy, PGE Kennedy, PGE Kennedy, PGE Kennedy, RL Carrier, S Ben Zirar, S Gibaud, SL Soignet, Stéphane Gibaud, T Loftsson, T Loftsson, V Lejon, VJ Stella   +45 more
core   +11 more sources

Population pharmacokinetics of tigecycline in critically ill patients

Frontiers in Pharmacology, 2023
Objective: In critically ill patients, the change of pathophysiological status may affect the pharmacokinetic (PK) process of drugs. The purpose of this study was to develop a PK model for tigecycline in critically ill patients, identify the factors ...
Xiangru Luo, Shiyi Wang, Dong Li, Jun Wen, Na Sun, Guangjun Fan   +5 more
doaj   +1 more source

Dose Optimization of Vancomycin for Critically Ill Patients Undergoing CVVH: A Prospective Population PK/PD Analysis

Antibiotics, 2021
The optimal dose of vancomycin in critically ill patients receiving continuous venovenous hemofiltration (CVVH) remains unclear. The objective of this study was to identify factors that significantly affect pharmacokinetic profiles and to further ...
Chuhui Wang, Chao Zhang, Xiaoxiao Li, Sixuan Zhao, Na He, Suodi Zhai, Qinggang Ge   +6 more
doaj   +1 more source

Pharmacokinetic/pharmacodynamic (PK/PD) simulation for dosage optimization of colistin and sitafloxacin, alone and in combination, against carbapenem-, multidrug-, and colistin-resistant Acinetobacter baumannii

Frontiers in Microbiology, 2023
To the best of our knowledge, to date, no study has investigated the optimal dosage regimens of either colistin or sitafloxacin against drug-resistant Acinetobacter baumannii (A. baumannii) infections by using specific parameters.
Vipavee Rodjun, Preecha Montakantikul, Jantana Houngsaitong, Kamonchanok Jitaree, Wichit Nosoongnoen   +4 more
doaj   +1 more source

A Large Impact of Obesity on the Disposition of Ivermectin, Moxidectin and Eprinomectin in a Canine Model: Relevance for COVID-19 Patients

Frontiers in Pharmacology, 2021
Ivermectin (IVM) and moxidectin (MOX) are used extensively as parasiticides in veterinary medicine. Based on in vitro data, IVM has recently been proposed for the prevention and treatment of COVID-19 infection, a condition for which obesity is a major ...
Alain Bousquet-Mélou, Anne Lespine, Jean-François Sutra, Isabelle Bargues, Pierre-Louis Toutain, Pierre-Louis Toutain   +5 more
doaj   +1 more source

Dosage regimen design

Pharmacology & Therapeutics, 1982
Pharmacology and Therapeutics 17 (1982) 143-163. doi:10.1016/0163-7258(82)90009-2 ; Received by publisher: 0000-01-01 ; Harvest Date: 2016-01-04 12:21:19 ; DOI:10.1016/0163-7258(82)90009-2 ; Page Range: 143 ...
Division of Clinical Pharmacokinetics, College of Pharmacy, University of Florida, Gainesville, FL 32610, U.S.A. ( host institution ), Lindsay DeVane, C. ( author ), Jusko, William J. ( author )   +2 more
openaire   +3 more sources

A Drug Dosage Table is a Useful Tool to Facilitate Prescriptions of Antiretroviral Drugs for Children in Thailand. [PDF]

, 2005
Scaling up of antiretroviral treatment (ART) for children in countries like Thailand will require decentralization and management by non-specialist doctors.
Eksaengsri, A, Frederix, K, Petdachai, W, Ponnet, M, Wilson, D, Zachariah, R   +5 more
core   +2 more sources

Effect of growth hormone administration on ameliorating pregnancy outcome in women with advanced maternal age and exploration of its optimized utilization

Frontiers in Endocrinology, 2023
BackgroundAge-related fertility decay is a great challenge for clinicians. Growth hormone (GH) supplementation has been studied as an adjuvant since late 1980s.
Qihui Feng, Yanbin Wang, Hongjing Han, Huan Shen   +3 more
doaj   +1 more source