Results 231 to 240 of about 188,637 (301)

Peptomer Linkers Enable Kinetic Control over Co‐Delivery of Multiple Chemotherapeutics

Advanced Healthcare Materials, EarlyView.
A key challenge in combinatorial chemotherapeutic drug delivery is independent control over release kinetics, especially with drugs of similar size and structure. Here, peptoid substitutions to proteolytically degradable peptides enabled the design of fast and slow‐releasing drug linkers.
Carolyn M. Watkins, Samuel L. Hallam, Mariah J. Austin, Adrianne M. Rosales   +3 more
wiley   +1 more source

Microneedle Technology in Psoriasis Management: Mechanistic Insights, Technological Innovation, Clinical Progress, and Challenges

Advanced Healthcare Materials, EarlyView.
This review explores the evolving role of microneedle systems in psoriasis management, highlighting their potential for enhanced drug delivery, diagnosis, and disease monitoring. It also discusses unmet clinical needs for psoriasis management and technical challenges, while outlining strategic directions to advance microneedle integration into routine ...
Fatma Moawad, Yasmine Ruel, Roxane Pouliot, Davide Brambilla   +3 more
wiley   +1 more source

Ti6Al4V‐Bioglass‐Copper Composites for Load‐Bearing Implants

Advanced Healthcare Materials, EarlyView.
We have designed and manufactured a novel Ti64‐based composite by adding 45S5 bioglass (BG) and copper (Cu). Adding BG on titanium improves wear resistance and biocompatibility, whereas Cu addition improves mechanical strength while providing inherent lifelong bacterial resistance.
Lochan Upadhayay, Bryson White, Susmita Bose, Amit Bandyopadhyay   +3 more
wiley   +1 more source

Nb2C‐Reinforced Hydrogel Microneedle as Dual ROS‐Scavenging Platform to Promote Diabetic Wound Healing

Advanced Healthcare Materials, EarlyView.
An advanced microneedle patch integrating niobium carbide nanosheets and curcumin is engineered for diabetic wound healing. The system enables dual ROS scavenging and NIR‐enhanced antimicrobial activity, effectively rebalancing the oxidative microenvironment, promoting macrophage repolarization and angiogenesis, and accelerating full‐thickness wound ...
Zhi Zheng, Heyan Huang, Xiangru Chen, Jie Fu, Zhiwei Sun, Mengjuan Tao, Jianwei Mao, Fei Zhang, Zhou Wan, Yuan Li, Dingan Wu, Chuchao Zhou, Yanqing Yang   +12 more
wiley   +1 more source

FDA-AACR Strategies for Optimizing Dosages for Oncology Drug Products: Selecting Optimized Dosages for Registrational Trials. [PDF]

Clin Cancer Res
Shord SS, Chen C, Jin JY, Van Wart S, Martin SK, Davidson BA, Liu J, LoRusso PM, Oxnard GR.   +8 more
europepmc   +1 more source

Higher Doses of Oral Propranolol for Resistant Infantile Haemangio-mas. [PDF]

Acta Derm Venereol
Dreyfus I, Dénos C, Boccara O, Barbarot S, Gagey-Caron V, Maruani A, Miquel J, Droitcourt C, Bigorre M, Martin L, Leauté-Labrèze C, Mazereeuw-Hautier J.   +11 more
europepmc   +1 more source

Therapeutic drug monitoring of amikacin in Chinese premature infant: a population pharmacokinetic analysis and dosage optimization. [PDF]

BMC Infect Dis
Li JH, Xu JH, Huang Y, Zhou M, Yang ZM, Li JJ, Feng ZT, Zhang Q, Yu YX, Duan LF, Tang L.   +10 more
europepmc   +1 more source

Dose Optimization of Tilmicosin against <i>Pasteurella multocida</i> in Swine by Physiologically Based Pharmacokinetic-Pharmacodynamic Model. [PDF]

J Agric Food Chem
Sun L, Zhang C, Mi K, Wang H, Pan Y, Tao Y, Huang L.   +6 more
europepmc   +1 more source

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REGIMEN OF DOSAGE

International Journal of Recent Research and Review, 2023
There has been some sort of misdiagnosis a lot of times when it comes to medicine, since every person is different and has different requirements according to factors like age, weight and other factors. Although a doctor generally has the knowledge regarding this and gives prescription accordingly, there can still be room for error.
Dr. Manish Gupta, Dr. Barkha Saxena, Aarushi Ghosh, Tanmay Meena   +3 more
openaire   +1 more source

Ethosuximide dosage regimens

Clinical Pharmacology & Therapeutics, 1976
A study was conducted in 9 children with petit mal epilepsy to compare the plasma levels of ethosuximide after divided daily administration with those after single daily administration. The children received their previously established dose in divided doses for 4 wk, in single morning doses for 4 wk, and again in divided doses for 4 wk.
R A, Buchanan, A W, Kinkel, J L, Turner, J C, Heffelfinger   +3 more
openaire   +2 more sources