Pharmaceutics, 2022 Antimicrobial resistance is a major public health issue. The pharmacokinetic/pharmacodynamic (PK/PD) model is an essential tool to optimize dosage regimens and alleviate the emergence of resistance.
Kun Mi +8 more
doaj +1 more source
Potency of marbofloxacin for pig pneumonia pathogens Actinobacillus pleuropneumoniae and Pasteurella multocida: Comparison of growth media [PDF]
, 2017 Pharmacodynamic properties of marbofloxacin were established for six isolates each of the pig respiratory tract pathogens, Actinobacillus pleuropneumoniae and Pasteurella multocida.
Dorey, L, Hobson, S, Lees, P
core +2 more sources
The Surgical Infection Society revised guidelines on the management of intra-abdominal infection [PDF]
, 2017 Background: Previous evidence-based guidelines on the management of intra-abdominal infection (IAI) were published by the Surgical Infection Society (SIS) in 1992, 2002, and 2010. At the time the most recent guideline was released, the plan was to update
Chang, Phillip K +11 more
core +3 more sources
Intracranial tuberculous mass lesions treated with thalidomide in an immunocompetent child from a low tuberculosis endemic country: A case report [PDF]
, 2018 Rationale: Tuberculous meningitis is a highly morbid, often fatal disease. Patient concern: We describe a case of an Italian child. Diagnoses: we diagnosed early a Tuberculous meningitis complicated by the occurrence of hydrocephalus, stroke, and ...
Ajassa, Camilla +8 more
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Population pharmacokinetics of nalbuphine in patients undergoing general anesthesia surgery
Frontiers in Pharmacology, 2023 Purpose: The aim of this study was to build a population pharmacokinetics (PopPK) model of nalbuphine and to estimate the suitability of bodyweight or fixed dosage regimen.Method: Adult patients who were undergoing general anesthetic surgery using ...
Xuyang Nie +8 more
doaj +1 more source
Indian Journal of Animal Sciences, 2014 Pharmacokinetics and testing of dosage regimen of cefazolin was carried out in 4 healthy female buffalo calves after its intravenous (iv) administration @ 10 mg/kg. Plasma and urine concentrations of cefazolin were estimated at various time intervals by
C JAYACHANDRAN, R K NIRALA, A K AGRAWAL
doaj +1 more source
Therapeutic dimensions of bisphosphonates: A clinical update
International Journal of Preventive Medicine, 2020 Bisphosphonates (BPs) are a commonly used class of drugs for the treatment of bone disorders. An extensive review of BPs with their clinical efficacy and safety profile is unavailable. This study aimed to review the available literature on BPs, summarize
Venkataramana Vannala +2 more
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Chloroquine dosage regimen simulation for pediatric patients with coronavirus disease 2019 [PDF]
Pharmaceutical Sciences Asia, 2022 Chloroquine (CQ) efficacy was shown in some coronavirus disease 2019 (COVID-19) adult clinical studies. However, its data in children is still limited.
Kiatkriangkrai Koyratkoson +3 more
doaj +1 more source
Possible dosage regimens for topical steroids assessed by vasoconstrictor assays using multiple applications [PDF]
, 1983 The bioavailabilities and activities of three amcinonide preparations and Betnovate cream were assessed using three multiple-dosage regimen vasoconstrictor assays in 10 volunteers.
Barry, B W, Haigh, J M, Woodford, R
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Population Pharmacokinetics and Dosing Regimen of Lithium in Chinese Patients With Bipolar Disorder
Frontiers in Pharmacology, 2022 Background: Lithium is an effective medication approved for the treatment of bipolar disorder (BD). It has a narrow therapeutic index (TI) and requires therapeutic drug monitoring.
Zi-bin Jin +7 more
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