Phase I dose-escalation trial of AMXT 1501 dicaprate plus difluoromethylornithine: a dual-agent approach targeting immunosuppressive polyamine metabolism. [PDF]
Piha-Paul SA +4 more
europepmc +1 more source
Objectives There is growing interest in evaluating new strategies to delay or prevent post‐traumatic osteoarthritis (PTOA) in individuals who have sustained anterior cruciate ligament (ACL) injury. This study sought to determine characteristics of potential treatments that are acceptable to patients with ACL injury.
Kevin Kennedy +9 more
wiley +1 more source
Labor Analgesia Initiation with Dural Puncture Epidural versus Standard Epidural Techniques: A Prospective Randomized Dose Allocation Study of Ropivacaine. [PDF]
Xiao F +6 more
europepmc +1 more source
Assessment of Pain Types in Recently Diagnosed Patients With Inflammatory Arthritis
Objective Up to 40% of patients with inflammatory arthritis (IA) experience persistent pain, traditionally thought to be associated with a shift from peripherally to centrally mediated pain during the disease course in some patients. We assessed sensory profiles of recently diagnosed individuals with IA, hypothesizing that pain reported at this early ...
Zoe Rutter‐Locher +8 more
wiley +1 more source
Anticholinergic burden and incident dementia: a Swedish nationwide case-control study. [PDF]
Zhu N +6 more
europepmc +1 more source
The impact of positive lifestyle behaviors on direct healthcare cost savings for low back pain
Objective This study aimed to investigate the relationship between a previously purpose‐developed lifestyle behavior scale and healthcare cost savings related to low back pain (LBP). Methods This longitudinal study utilised data from the AUstralian Twin BACK (AUTBACK) study. LBP and lifestyle behavior measures were collected at baseline.
Ye Tian +8 more
wiley +1 more source
IDeate-Lung02: a Phase 3 study of second-line ifinatamab deruxtecan in patients with relapsed small cell lung cancer. [PDF]
Owonikoko TK +11 more
europepmc +1 more source
Objective This study investigates the association between discordance in commonly collected clinical indicators of rheumatoid arthritis (RA) disease activity and abnormalities in quantitative sensory testing (QST) observed in individuals with nociplastic pain.
Clarice P. Lin +10 more
wiley +1 more source
Clinical predictors and concomitant antiseizure medications effects on seizure control in relation to plasma cenobamate concentration: a multicenter retrospective study. [PDF]
Operto FF +17 more
europepmc +1 more source
Financial Distress and its Determinants in Rheumatoid Arthritis
Objective To quantify the degree of financial distress and identify its determinants in adults with rheumatoid arthritis (RA) given the frequent chronic use of expensive disease modifying therapies. Methods We identified adults enrolled in the FORWARD databank with either RA or non‐inflammatory musculoskeletal disease (NIMSKD) completing the Functional
Amber Brown Keebler +5 more
wiley +1 more source

