Results 201 to 210 of about 931,718 (350)

Development of a Personalized Visualization and Analysis Tool to Improve Clinical Care in Complex Multisystem Diseases With Application to Scleroderma

Arthritis Care &Research, EarlyView.
Objective In complex diseases, it is challenging to assess a patient's disease state, trajectory, treatment exposures, and risk of multiple outcomes simultaneously, efficiently, and at the point of care. Methods We developed an interactive patient‐level data visualization and analysis tool (VAT) that automates illustration of the trajectory of a ...
Ji Soo Kim, John Scott, Lauren Fisher, Lauren N. Smith, Willie Stewart, Adrianne Woods, Rob Smithwright, Diane Koher, Parastoo Aslanbeik, Aalok B. Shah, Brad Tibbils, Samantha I. Pitts, Ayse P. Gurses, Yushi Yang, Ana‐Maria Orbai, Antony Rosen, Laura K. Hummers, Scott L. Zeger, Ami A. Shah   +18 more
wiley   +1 more source

Blood Pressure Reduction During Anesthetic Induction with Remimazolam versus Propofol in Elderly Patients: Pharmacodynamic Modeling of Remimazolam. [PDF]

Drug Des Devel Ther
Oh J, Kim KM, Sim JH, Lee EK, Choi BM.
europepmc   +1 more source

Dose response relationships in the evaluation of the effect of drugs on allergen and histamine induced skin wheals

Journal of Allergy and Clinical Immunology, 1982
M.J. Phillips, R. Thomas, R.J. Davies
openaire   +1 more source

AGE-DEPENDENT DOSE-RESPONSE RELATIONSHIP OF ORG NC45 IN ANAESTHETIZED PATIENTS

, 1982
A. d'Hollander, F. Massaux, M. Nevelsteen, S. Ágoston   +3 more
semanticscholar   +1 more source

Preferences for post‐traumatic osteoarthritis prevention strategies in individuals with anterior cruciate ligament injury

Arthritis Care &Research, Accepted Article.
Objectives There is growing interest in evaluating new strategies to delay or prevent post‐traumatic osteoarthritis (PTOA) in individuals who have sustained anterior cruciate ligament (ACL) injury. This study sought to determine characteristics of potential treatments that are acceptable to patients with ACL injury.
Kevin Kennedy, Lily Waddell, Adam Easterbrook, Jeffrey N. Katz, Cale Jacobs, Morgan Jones, Faith Selzer, Elena Losina, Liana Fraenkel, Nick Bansback   +9 more
wiley   +1 more source

FDA-AACR Strategies for Optimizing Dosages for Oncology Drug Products: Early-Phase Trials Using Innovative Trial Designs and Biomarkers. [PDF]

Clin Cancer Res
Okusanya OO, Patilea-Vrana GI, Sireci A, Iasonos A, Davidson BA, Liu J, Shord SS, LoRusso PM, Yap TA.   +8 more
europepmc   +1 more source

Assessment of Pain Types in Recently Diagnosed Patients With Inflammatory Arthritis

Arthritis Care &Research, EarlyView.
Objective Up to 40% of patients with inflammatory arthritis (IA) experience persistent pain, traditionally thought to be associated with a shift from peripherally to centrally mediated pain during the disease course in some patients. We assessed sensory profiles of recently diagnosed individuals with IA, hypothesizing that pain reported at this early ...
Zoe Rutter‐Locher, Sam Norton, Joseph L. Taylor, Bina Menon, Tom Esterine, Ruth Williams, Leonie S. Taams, Kirsty Bannister, Bruce W. Kirkham   +8 more
wiley   +1 more source

Towards new approach methodologies for biological therapeutics: a novel model-informed metric to assess immunogenicity risk. [PDF]

Front Immunol
Rose RH, Shuaib A, Wigbers M, Khalifa M, Kierzek AM, van der Graaf PH.   +5 more
europepmc   +1 more source

The Nephrotoxicity of Vancomycin. [PDF]

, 2017
Farber, John L., Filippone, Edward J., Kraft, Walter K.   +2 more
core   +2 more sources

The Effect of Nitrous Oxide on the Dose-Response Relationship of Rocuronium

Anesthesia and Analgesia, 2005
A. Kopman, W. Chin, J. Moe, R. Malik
semanticscholar   +1 more source