Results 251 to 260 of about 707,752 (308)

Probing Early Particle‐Cell Membrane Interactions via Single‐Cell and Single‐Particle Interaction Analysis

Advanced Functional Materials, EarlyView.
The pre‐internalization phase of endocytosis remains poorly characterized at single‐cell levels. Single‐cell pre‐internalization mechanics are investigated using advanced robotic techniques. Cancer cells exhibit biphasic adhesion – rapid initial binding followed by reinforcement – while fibroblasts show gradual engagement.
Houari Bettahar, Christos Tapeinos, Oğulcan Işıtman, Carmine D'Amico, Alexandra Correia, Hélder A. Santos, Quan Zhou   +6 more
wiley   +1 more source

Ferroelectricity in Single‐Crystalline BaTiO3 Nanodisks on Silicon

Advanced Functional Materials, EarlyView.
Ferroelectricity is studied in 20 nm thick single crystalline BaTiO3 nanodisks when scaling their diameter from ≈ 400 down to 100 nm. For 100 nm diameter, the vertical polarization component adopts three distinct patterns, and the lateral one shows a rotational invariance in‐plane, suggesting a combination of center‐type and flux‐closure domains.
Ibukun Olaniyan, Jürgen Albert, Beatriz Canabarro, Haidong Lu, Sven Wiesner, Nikolay Cherkashin, Alexei Gruverman, Sylvie Schamm‐Chardon, Dong‐Jik Kim, Catherine Dubourdieu   +9 more
wiley   +1 more source

The role of neoantigens and tumor mutational burden in cancer immunotherapy: advances, mechanisms, and perspectives. [PDF]

J Hematol Oncol
Sun S, Liu L, Zhang J, Sun L, Shu W, Yang Z, Yao H, Zhang Z.   +7 more
europepmc   +1 more source

Metal Nanoclusters for Cancer Imaging and Treatment

Advanced Functional Materials, EarlyView.
This review aims to provide a comprehensive summary and discussion of the core–shell design capabilities of metal nanoclusters (NCs) at the atomic level for cancer imaging and treatment. It offers essential insights into the design principles of metal NCs while also encouraging the exploration of other nanomaterials and their potential theranostic ...
Haiguang Zhu, Ziping Wang, Qiaofeng Yao, Ping Zhang, Jianping Xie, Xun Yuan   +5 more
wiley   +1 more source

DPD Ultra-Rapid Metabolizer Status and Efficacy of 5-Fluorouracil Treatment: A Real-World Study. [PDF]

Fundam Clin Pharmacol
Kallee G, Milano G, Duffaud F, Dahan L, Ciccolini J.   +4 more
europepmc   +1 more source

Mathematical Modeling of Andrographolide Therapy Effects and Immune Response in In Vivo Dynamics of SARS-CoV-2 Infection. [PDF]

Viruses
Yarnvitayalert P, Saleewong T.
europepmc   +1 more source

Concentration-Response Analysis of the Combination of Pyronaridine and Piperaquine on Corrected QT Interval From a Randomized, Double-Blind, Placebo-Controlled Study in Healthy Adults of African Sub-Saharan Origin. [PDF]

Clin Transl Sci
Felices M, Borghini-Fuhrer I, Abla N, Chalon S.   +3 more
europepmc   +1 more source

Population Pharmacokinetic and Pharmacokinetic-Pharmacodynamic Modeling of Serum M-Protein Response for Modakafusp Alfa in a Phase 1/2 Study of Patients With Relapsed or Refractory Multiple Myeloma. [PDF]

Clin Transl Sci
Li C, Santulli A, Van Wart S, Yang L, Suryanarayan K, Cook SF, Parot X, Mager DE, Gupta N.   +8 more
europepmc   +1 more source

Model-Informed Drug Development-Based Bridging from Subcutaneous to Intravenous Secukinumab Dosing: Approval in Psoriatic Arthritis and Axial Spondyloarthritis. [PDF]

Clin Pharmacol Ther
Dumortier T, Valenzuela G, Churchill M, Mijatovic J, Bruin G, Pricop L, Richards H, Renard D, Singhal A, Marathe A.   +9 more
europepmc   +1 more source