Results 281 to 290 of about 925,610 (310)

An exposure-safety analysis to support the dosage of the novel AKT inhibitor capivasertib. [PDF]

open access: yesCancer Chemother Pharmacol
Teruel CF   +4 more
europepmc   +1 more source

Understanding therapeutic tolerance through a mathematical model of drug-induced resistance. [PDF]

open access: yesNPJ Syst Biol Appl
Gevertz JL   +4 more
europepmc   +1 more source

A Comparative Dose-response Relationship Between Sexes for Mortality and Morbidity of Radiation-induced Lung Injury in the Rhesus Macaque

Health Physics, 2019
Radiation-induced lung injury is a characteristic, dose- and time-dependent sequela of potentially lethal, delayed effects of acute radiation exposure. Understanding of these delayed effects to include development of medical countermeasures requires well-
K. Thrall   +5 more
semanticscholar   +1 more source

PhXA34, a new potent ocular hypotensive drug. A study on dose-response relationship and on aqueous humor dynamics in healthy volunteers.

A M A Archives of Ophthalmology, 1991
The prostaglandin analogue PhXA34 was tested in two studies in normal human eyes; 1, 3, and 10 micrograms of PhXA34 reduced the intraocular pressure by about 2, 3, and 4 mm Hg, respectively, 6 to 10 hours after a single topical dose. The only side effect
Albert Alm, J. Villumsen
semanticscholar   +1 more source

Treatment intensity and reduction in drug use for cocaine-dependent methadone patients: a dose-response relationship.

Journal of Psychoactive Drugs, 1995
This study examined the impact of treatment intensity on cocaine use. Seventy-seven cocaine-using methadone patients were enrolled in a six-month, structured, manual-driven, cognitive-behavioral treatment program.
A. Rosenblum   +6 more
semanticscholar   +1 more source

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