Results 281 to 290 of about 435,631 (309)

Toxic Effects of Nonsteroidal Anti-Inflammatory Drugs in Overdose

Drug Safety, 1990
Nonsalicylate, nonsteroidal anti-inflammatory drugs (NSAIDs) can be divided into 4 chemical classes: acetic acids, fenamic acids, oxicams and propionic acids. Most NSAID overdoses result in a benign outcome. Of 50,614 exposures reported to poison centres in the United States in a 2-year period, 131 (0.26%) had a major outcome, with 10 deaths.
S C, Smolinske, A H, Hall, S A, Vandenberg, D G, Spoerke, P V, McBride   +4 more
openaire   +2 more sources

Dose-response relationships for the antipsychotic effects and Parkinsonian side-effects of typical neuroleptic drugs: Practical and theoretical implications

Progress in Neuro-Psychopharmacology and Biological Psychiatry, 1997
1. From a review of published literature it is concluded that the minimum dose of a neuroleptic drug (NLD) required to alleviate psychosis is very similar to that producing minimal parkinsonian side effects (PSE). This conclusion is reached both from group comparisons and individual comparisons of dose/response relations (DRR) for the two effects. 2. A
openaire   +2 more sources

Effects of drugs on nondiscriminated avoidance behavior

Psychopharmacologia, 1964
Thirteen male, Long-Evans rats were trained to press a lever to postpone a brief electric shock. Each rat was subjected to several different doses of chlorpromazine, d-amphetamine, atropine and benactyzine, and then tested for four hours under a mixed schedule of extinction and nondiscriminated avoidance behavior.
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The effect of some cholinolytic drugs on a number of behavioural parameters measured in the T-maze alternation test: Dose-response relationships

Psychopharmacologia, 1974
Conflict behaviour in a T-maze can be observed at the choice point, involving simultaneous tendencies to move left and right and in the goal box involving simultaneous tendencies to approach the reward and to return towards the choice point. Firstly, the effects of different doses (from 0.06 to 1 mg/kg) of the cholinolytic drug 3-quinuclidinyl ...
openaire   +2 more sources

Drug levels, anti-drug antibodies and B-cell counts were not predictive of response in rheumatoid arthritis patients on (ultra-)low-dose rituximab

Rheumatology, 2022
Nathan Den Broeder, Maike Wientjes
exaly  

Exploration of a dose-response relationship in schizophrenia with the novel antipsychotic drug olanzapine

European Neuropsychopharmacology, 2001
B.J. Kinon, L. Wang, J.A. Gilmore
openaire   +1 more source

P.445 Dose-response relationships of antipsychotic drugs for major depressive disorder: a systematic review and meta-analysis

European Neuropsychopharmacology, 2020
S. Kurokawa, T. Kishimoto, K. Hagi, J. Kane, C. Correll   +4 more
openaire   +1 more source

A Bayesian model of dose-response for cancer drug studies

Annals of Applied Statistics, 2022
Wesley Tansey, David Blei
exaly  

Searching for Drug Synergy in Complex Dose–Response Landscapes Using an Interaction Potency Model

Computational and Structural Biotechnology Journal, 2015
Jing Tang, Tero Aittokallio, Krister Wennerberg   +2 more
exaly  

Do vertical shifts in dose-response rate-relationships in operant conditioning procedures indicate ?sensitization? to ?drug wanting??

Psychopharmacology, 2004
Gerald, Zernig, Gudrun, Wakonigg, Ekkehard, Madlung, Christian, Haring, Alois, Saria   +4 more
openaire   +2 more sources