Efikasnost terapijskog monitoringa ciklosporina određivanjem C2 i PIK0−4 tokom prva 24 meseca posle transplantacije bubrega [PDF]
Vojnosanitetski Pregled, 2008 Background/Aim. Cyclosporine (CyA) therapeutic drug monitoring (TDM) through the measurement of drug concentration in blood two hours after the administration (C2), and/or according to the calculated value of the area under the concentration - time curve
Vavić Neven +5 more
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Acute drug effects on habitual and non-habitual responding in crossed high alcohol preferring mice [PDF]
, 2018 RATIONALE: Drug reward plays a central role in acquiring drug-seeking behavior. However, subjects may continue using drugs despite negative consequences because self-administration becomes habitual, and divorced from outcome values. Although a history
Grahame, Nicholas J., Houck, Christa A.
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Sugammadex ED90 dose to reverse the rocuronium neuromuscular blockade in obese patients
Revista do Colégio Brasileiro de CirurgiõesObjective: to determine the ED90 (minimum effective dose in 90% of patients) of sugammadex for the reversal of rocuronium-induced moderate neuromuscular blockade (NMB) in patients with grade III obesity undergoing bariatric surgery.
MAURO PRADO DA SILVA +5 more
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Prediction of disease progression, treatment response and dropout in chronic obstructive pulmonary disease (COPD). [PDF]
, 2014 Drug development in chronic obstructive pulmonary disease (COPD) has been characterised by unacceptably high failure rates. In addition to the poor sensitivity in forced expiratory volume in one second (FEV1), numerous causes are known to contribute to ...
Danhof, M +6 more
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Frontiers in Pharmacology, 2014 Although many antipsychotics can reasonably control positive symptoms in schizophrenia, patients’ return to society is often hindered by negative symptoms and cognitive deficits.
Hugo eGeerts +4 more
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Current Concepts on Drug Abuse and Dependence [PDF]
, 2015 Drug addiction is a complex disease characterized by compulsive and uncontrollable desire to seek and consume the drug. In time, drug-related terminology has undergone many changes, arising from the deepening of the mechanisms of action, but also about ...
Baconi, Daniela Luiza +5 more
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Aspects of the Relationship between Drug Dose and Drug Effect
Dose-Response, 2009 It is generally assumed that there exists a well-defined relationship between drug dose and drug effect and that this can be expressed by a dose-response curve.
Abraham Peper
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Two-compartment pharmacokinetic model of itraconazole after single oral dose administration - gender differences [PDF]
Vojnosanitetski PregledBackground/Aim. Itraconazole (ICZ) is a widely used antifungal drug with hypervariable pharmacokinetics (PK), which is the result of the molecule’s nature itself, as well as the influence of multiple factors.
Miljković Milijana +4 more
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Revista Contexto & SaúdeThis study evaluated the in vivo giardicidal potential of black tea (Camellia sinensis) in male Swiss mice experimentally infected with 104 cysts of Giardia duodenalis assemblage BIV.
Liara Izabela Lopes Romera +5 more
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New approaches to measuring anthelminthic drug efficacy: parasitological responses of childhood schistosome infections to treatment with praziquantel [PDF]
, 2015 By 2020, the global health community aims to control and eliminate human helminthiases, including schistosomiasis in selected African countries, principally by preventive chemotherapy (PCT) through mass drug administration (MDA) of anthelminthics ...
A Danso-Appiah +75 more
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