Results 41 to 50 of about 757,481 (306)

Amoxicillin/Metronidazole Dose Impact as an Adjunctive Therapy for Stage II - III Grade C Periodontitis (Aggressive Periodontitis) at 3- And 6-Month Follow-Ups: a Systematic Review and Meta-Analysis

eJournal of Oral Maxillofacial Research, 2022
Objectives: This systematic review and meta-analysis study sought to review the efficacy of amoxicillin/metronidazole dose and duration time in the treatment of stage II - III grade C periodontitis (aggressive periodontitis) after current follow-up ...
Malihe Karrabi, Zahra Baghani
doaj   +1 more source

Effects of scopolamine on matching to sample paradigm and related tests in human subjects [PDF]

, 2003
This was a double-blind placebo-controlled study with a cross-over design to examine the effects of scopolamine on cognitive functions in young healthy subjects.
Adam, M., Engel, R., Kathmann, N., Koller, G., Satzger, W., Soyka, Michael, Wagner, M.   +6 more
core   +1 more source

Aspects of the Relationship between Drug Dose and Drug Effect

Dose-Response, 2009
It is generally assumed that there exists a well-defined relationship between drug dose and drug effect and that this can be expressed by a dose-response curve.
Abraham Peper
doaj   +1 more source

Two-compartment pharmacokinetic model of itraconazole after single oral dose administration - gender differences [PDF]

Vojnosanitetski Pregled
Background/Aim. Itraconazole (ICZ) is a widely used antifungal drug with hypervariable pharmacokinetics (PK), which is the result of the molecule’s nature itself, as well as the influence of multiple factors.
Miljković Milijana, Kovačević Aleksandra, Mikov Momir, Stanojković Tijana, Dragojević-Simić Viktorija   +4 more
doaj   +1 more source

Retrospective Analysis Using Pharmacokinetic/Pharmacodynamic Modeling and Simulation Offers Improvements in Efficiency of the Design of Volunteer Infection Studies for Antimalarial Drug Development

Clinical and Translational Science, 2021
Volunteer infection studies using the induced blood stage malaria (IBSM) model have been shown to facilitate antimalarial drug development. Such studies have traditionally been undertaken in single‐dose cohorts, as many as necessary to obtain the dose ...
Kayla Ann Andrews, Joel S. Owen, James McCarthy, David Wesche, Nathalie Gobeau, Thaddeus H. Grasela, Jörg J. Möhrle   +6 more
doaj   +1 more source

Sorafenib dose escalation is not uniformly associated with blood pressure elevations in normotensive patients with advanced malignancies. [PDF]

, 2014
Hypertension after treatment with vascular endothelial growth factor (VEGF) receptor inhibitors is associated with superior treatment outcomes for advanced cancer patients.
Bakris, GL, Cohen, EEW, Fleming, GF, House, LK, Karovic, S, Karrison, TG, Levine, MR, Maitland, ML, Ratain, MJ, Rudek, MA, Thomeas, V, Wen, Y, Wright, JJ, Wu, K   +13 more
core   +2 more sources

Giardicidal effect of black tea (camellia sinensis) in the treatment of giardia duodenalis in swiss mice

Revista Contexto & Saúde
This study evaluated the in vivo giardicidal potential of black tea (Camellia sinensis) in male Swiss mice experimentally infected with 104 cysts of Giardia duodenalis assemblage BIV.
Liara Izabela Lopes Romera, Cristiane Maria Colli, Amanda Gubert Alves dos Santos, Gessilda de Alcântara Nogueira de Melo, Ariana Ferrari, Mônica Lúcia Gomes   +5 more
doaj   +1 more source

Reasoning deficits among illicit drug users are associated with aspects of cannabis use [PDF]

, 2014
Background. Deficits in deductive reasoning have been observed among ecstasy/polydrug users. The present study seeks to investigate dose-related effects of specific drugs and whether these vary with the cognitive demands of the task. Methods. One hundred
AB Scholey, Andy M. Morley, AS Gilinsky, BF Zaldívar, C Montgomery, C Reverberi, C Reverberi, C Shikishima, C Shikishima, C Vignali, Catharine Montgomery, D Rodriguez-Moreno, F Hadjiefthyvoulou, F Indlekofer, Florentia Hadjiefthyvoulou, G Bedi, G Jager, G Jager, G Kanayama, GS Yacoubian Jr, J Raven, JE Fisk, JM Bland, John E. Fisk, KJ Gilhooly, KJ Gilhooly, KM Galotti, LK Jacobsen, M Bucciarelli, MJ Fernández-Serrano, MW Morris, N Pike, N Verschueren, PJ Cunha, PN Johnson-Laird, PN Murphy, S Khemlani, S Nakagawa, SR Narum, V Goel, Y Benjamini   +40 more
core   +3 more sources

Comparing Two Different Doses of Intravenous Midazolamin in Pediatric Sedation and Analgesia

Archives of Academic Emergency Medicine, 2018
Introduction: Midazolam has turned into a common drug for pediatric procedural sedation and analgesia. However, there is not much data regarding its proper dose and potential side effects in the Iranian children population.
Hassan Barzegari, Arash Forouzan, Kambiz Masoumi, Hassan Motamed, Behzad Zohrevandi, Shima Zeynadini Meymand   +5 more
doaj   +1 more source

Estimating the turnover time of high intravenous intake of vitamin C [PDF]

Archive of Oncology, 2011
Background: Intravenous dosing is generally recognized to be the only effective means of maintaining a high concentration of vitamin C in the plasma.
Wong Alfred
doaj   +1 more source