Results 71 to 80 of about 419,320 (165)

CDCR-Rank: a computational model for predicting drug combination dose response using ranking-based optimization. [PDF]

Bioinform Adv
Moragheb M, Abbasi K, Razzaghi P, Dehghan A, Gharaghani S.   +4 more
europepmc   +1 more source

Estimated Oral Semaglutide Exposure Has Distinct Relationships With Glycaemic Response, Weight Loss and Gastrointestinal Tolerability. [PDF]

Diabetes Obes Metab
Fadini GP, Morieri ML, Boscaro C, Bonora BM, Cignarella A.   +4 more
europepmc   +1 more source

Optimizing Oligonucleotide Therapeutics: A Model-Informed Drug Development Perspective. [PDF]

Clin Transl Sci
Yuan Y, Sharma V, Bhattaram VA, Pan X, Earp J, Wang Y, Liu J, Zhu H.   +7 more
europepmc   +1 more source

Exposure-safety analyses of talazoparib in combination with enzalutamide in patients with metastatic castration-resistant prostate cancer (mCRPC) in the TALAPRO-2 trial. [PDF]

J Pharmacokinet Pharmacodyn
Wang Y, Hadigol M, Lincha VR, Hoffman J, Azad AA, Agarwal N, Matsubara N, Zohren F, DeAnnuntis L, Wang DD.   +9 more
europepmc   +1 more source

Exposure/Response vs. Dose/Response Relationships in Drug Development

BMC News and views, 2003
openaire   +1 more source

Impact of CFTR modulator concentrations on clinical response in cystic fibrosis. [PDF]

Eur Respir J
Chalamalla AR, Baker E, Ryan KJ, Dowell A, Natt JR, Zemanick ET, Konstan MW, Mayer-Hamblett N, Acosta EP, Guimbellot JS, CHEC-SC investigators.   +10 more
europepmc   +1 more source

Causal Directed Acyclic Graphs to Mitigate Confounding Bias in Exposure-Response Analyses. [PDF]

CPT Pharmacometrics Syst Pharmacol
Goulooze SC, Vong C, Hu C, Dumortier T, Mercier F.   +4 more
europepmc   +1 more source

Talquetamab: Mechanism of Action, Clinical, and Translational Science. [PDF]

Clin Transl Sci
Wang Y, Gong J, Au N, Zhou J, Yuan D, Tolbert J, Zhang G, Vishwamitra D, Zhang J, Haddish-Berhane N, Singh I.   +10 more
europepmc   +1 more source

Dose response relationships in the evaluation of the effect of drugs on allergen and histamine induced skin wheals

Journal of Allergy and Clinical Immunology, 1982
M.J. Phillips, R. Thomas, R.J. Davies
openaire   +1 more source

Pitfalls in the pharmacotherapy of hypertension. [PDF]

Clin Med (Lond)
McNally RJ, Amran M, Ferro A, Maniero C, Taddei S, Faconti L.   +5 more
europepmc   +1 more source