Results 81 to 90 of about 419,320 (165)

Longitudinal Tumor Size and Survival Modeling for Exposure-Response Analysis of Drugs with Frequent Dose Reductions: Dose Justification of Abemaciclib in Patients with Metastatic Breast Cancer. [PDF]

Clin Pharmacol Ther
Chigutsa E, Chapman SC, Turner PK.
europepmc   +1 more source

EC₅₀ and EC₉₅ of Epidural Ropivacaine for Intraoperative Analgesia During High-Intensity Focused Ultrasound for Adenomyosis: A Prospective Double-Blind Up-and-Down Concentration-Finding Study. [PDF]

Drug Des Devel Ther
Yang S, Zhang Y, Yang F, Luo L.
europepmc   +1 more source

Controlled Maxillofacial Administration of Levodopa in a Patient With Parkinson's Disease: A First-in-Human 24-Hour Follow-Up Study. [PDF]

Cureus
Thirunavukarasu SC, Ramanan BBV, Varadharaj D, Arumugam D, Poyyadhappan J, Moorthy D, Benjamin SD, Verma K, Sudhakar J, Janardhanan HA, Ur A.   +10 more
europepmc   +1 more source

Effectiveness of low-dose perampanel in focal epilepsy patients aged twelve or older in Southern China: an observational study. [PDF]

Sci Rep
Lu X, Deng Y, Shi X, Feng Y, Zheng J, Wu Y, Yu L.   +6 more
europepmc   +1 more source

Clinical Pharmacology and Translational Science Considerations in the Development of Dual-Payload Antibody Drug Conjugates. [PDF]

Clin Transl Sci
Ravenstijn P, Kakinuma T, Hamed S, Kadokura T, Okada Y, Poondru S.   +5 more
europepmc   +1 more source

An observational cohort study evaluating adalimumab concentrations for predicting non-recapture of biochemical response after dose escalation in patients with Crohn's disease experiencing secondary loss of response. [PDF]

J Can Assoc Gastroenterol
De Marco D, McHugh K, Plamondon S, Rioux LC, Steinhart AH, Horvat M, Afif W.   +6 more
europepmc   +1 more source

Antipsychotic dose and efficacy for acute schizophrenia spectrum disorders: an updated systematic review and dose-response meta-analysis. [PDF]

EClinicalMedicine
Furukawa Y, Lin X, Rodolico A, Tian J, Wu H, Schneider-Thoma J, Priller J, Davis JM, Leucht S, Siafis S.   +9 more
europepmc   +1 more source

Antiseizure Effects of Cannabidiol in Combination With Cannabigerol in the Maximal Electroshock Seizure Model. [PDF]

Basic Clin Pharmacol Toxicol
Zhou HZ, Scott BW, Oleksak YI, Burnham WM.   +3 more
europepmc   +1 more source

Pharmacokinetics and Exploratory Exposure-Response Analysis of Chikusetsusaponin IVa in Myocardial Ischemia/Reperfusion-Injured Rats. [PDF]

Pharmaceuticals (Basel)
Shuai X, Wang H, Luo J, Zeng Y, Wang Y, Zhu L, Liu Z, Cheng Y.   +7 more
europepmc   +1 more source

Efficacy, Safety and PK of Once-Daily Oral Semaglutide 25 mg for Obesity With and Without Type 2 Diabetes in Comparison With Subcutaneous Semaglutide 2.4 mg: A Model-Informed Drug Development Approach. [PDF]

Diabetes Obes Metab
Overgaard RV, Birkhan O, Rathor N, Sparsø T, Strathe A, Wharton S, Rubino D.   +6 more
europepmc   +1 more source