Results 101 to 110 of about 419,320 (165)

Population Pharmacokinetic/Pharmacodynamic Modeling of Therapeutic Enzymes in Lysosomal Storage Diseases. [PDF]

Clin Pharmacokinet
Barzel I, van der Ploeg AT, Pijnappel WWMP, van der Kuy PHM, van den Hout JMP, Preijers T.   +5 more
europepmc   +1 more source

Uncertainty undermines the validity of antimicrobial pharmacodynamics. [PDF]

J Pharmacokinet Pharmacodyn
Woodward AP.
europepmc   +1 more source

Elranatamab: Mechanism of Action, Clinical, and Translational Science. [PDF]

Clin Transl Sci
Elmeliegy M, Viqueira A, Vandendries E, Soltantabar P, Lon HK, Poels K, Shtylla B, Irby D, Bompiani-Myers K, O'Brien T, Hibma J.   +10 more
europepmc   +1 more source

Evaluation of Growth Differentiation Factor 15 as an Early Biomarker of Anthracycline-Induced Cardiotoxicity Using an Integrated PK/PD Model. [PDF]

Clin Transl Sci
Dabour MS, Blaes AH, Jacobson PA, Kirstein MN, Zordoky BN, Cheng S.   +5 more
europepmc   +1 more source

Efficacy, Safety and Pharmacokinetics of Semaglutide 1.7 mg for Obesity Treatment in Adolescents: A Model-Informed Drug Development Approach. [PDF]

Diabetes Obes Metab
Strathe A, Bomberg EM, Jensch G, Kildegaard J, Harder-Lauridsen NM, Weghuber D, Overgaard RV.   +6 more
europepmc   +1 more source

The association of the Healthy Lifestyle Index (HLI) and HLI trajectories with risk of all-cause and cause-specific mortality: a GRADE-assessed dose-response systematic review and meta-analysis. [PDF]

BMJ Open
HasanRashedi M, Norouzzadeh M, Gohari Dezfuli Z, Jamshidi S, Mehdipoor F, Ghoreishy SM, Teymoori F, Shidfar F, Eskandari R.   +8 more
europepmc   +1 more source

Metformin-Associated Gastrointestinal Intolerance: A Narrative Review of Mechanisms and Clinical Management. [PDF]

Clin Med Insights Endocrinol Diabetes
Chen S, Xu B, Lu M.
europepmc   +1 more source

Safety and Efficacy of HexaBody-DR5/DR5 in Malignant Solid Tumors: Phase 1/2a Results and Translational Insights Into Observed Hepatotoxicity. [PDF]

Clin Transl Sci
Overdijk MB, Strumane K, Plummer R, LoRusso P, Rodon Ahnert J, Banerji U, Garralda E, Calvo E, Si H, Hoevenaars N, Mortensen JT, Bosgra S, Malmberg A, Ellekilde-Pedersen M, Ramirez-Andersen T, Diamantopoulou Reiter P, Favaro E, Forssmann U, Breij ECW, Jure-Kunkel M.   +19 more
europepmc   +1 more source

Rethinking immunogenicity: an integrated approach reveals the PK/PD impact of pre-existing and drug-sustaining ADA. [PDF]

Bioanalysis
Mehta D, Wargin W, Wallace-Teliz S, Stevenson LF, Rigdon G.   +4 more
europepmc   +1 more source