Results 191 to 200 of about 1,297,078 (335)

Systemic T Cell Receptor Profiling Reveals Adaptive Immune Activation and Potential Immune Signatures of Diagnosis and Brain Atrophy in Epilepsy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Epilepsy is increasingly associated with immune dysregulation and inflammation. The T cell receptor (TCR), a key mediator of adaptive immunity, shows repertoire alterations in various immune‐mediated diseases. The unique TCR sequence serves as a molecular barcode for T cells, and clonal expansion accompanied by reduced overall TCR ...
Yong‐Won Shin, Sang Bin Hong, Yong Woo Shin, Inpyeong Hwang, Jaeseong Oh, Jihyeon Choi, Narae Kim, Jangsup Moon, Keun‐Hwa Jung, Kyung‐Il Park, Ki‐Young Jung, Kon Chu, Sang Kun Lee   +12 more
wiley   +1 more source

Dose-Response Relationship of Single Oral Doses of Guanabenz in Hypertensive Patients

, 1984
Donald J. Weidler, Dyal C. Garg, Nader S. Jallad   +2 more
openalex   +1 more source

Exosome Proteomics of SOD1D90A Mutation Suggest Early Disease Mechanisms, and FN1 as a Biomarker

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Amyotrophic lateral sclerosis (ALS) is a neuromuscular disease. Super oxide dismutase 1 (SOD1) gene mutations cause ALS, and the D90A mutation is associated with primarily upper motor neuron (UMN) loss. Objective Our goal is to reveal the early cellular events in ALS pathology and identify potential pharmacokinetic biomarkers, using well ...
Mukesh Gautam, Ali Laith, Aslihan Gunel, Melda Yilmaz, Nazli Basak, Halil Idrisoglu, P. Hande Ozdinler   +6 more
wiley   +1 more source

[Dose-response relationship in the incidence of urinary bladder carcinoma in mice by implanting pellets containing a chemical carcinogen].

, 1982
Chise Hashida, Naoko KOIKE, Kazuyuki Nagayama, Takayuki SUZUKI, Iwao AKIYAMA, Nozomi Takemura   +5 more
openalex   +2 more sources

Why Dosing Matters: A Closer Look at the Dose-Response Relationship With OnabotulinumtoxinA. [PDF]

J Cosmet Dermatol
Philipp-Dormston WG, Joseph JH, Carruthers JDA, Fezza JP, Mukherjee M, Yasin A, Musumeci M.   +6 more
europepmc   +1 more source

Interleukin‐6 as a Key Biomarker in Facioscapulohumeral Dystrophy: Evidence From Longitudinal Analyses

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Facioscapulohumeral muscular dystrophy type 1 (FSHD1) is a progressive neuromuscular disorder with no approved treatments. Identifying reliable biomarkers is critical to monitor disease severity, activity, and progression. Interleukin‐6 (IL‐6) has been proposed as a candidate biomarker, but longitudinal validation is limited ...
Jonathan Pini, Emanuela Martinuzzi, Sandra Dhifallah, Abderhmane Slioui, Angela Puma, Luisa Villa, Michele Cavalli, Andra Ezaru, Jérémy Garcia, Manuela Gambella, Federico Torre, Luca Jacopo Pavan, Nicolas Glaichenhaus, Sabrina Sacconi   +13 more
wiley   +1 more source

Analgesia, Pruritus, and Ventilation Exhibit a Dose-Response Relationship in Parturients Receiving Intrathecal Fentanyl During Labor

, 1999
Norman L. Herman, Kue C. Choi, Paul J. Affleck, Randy Calicott, Reid Brackin, Anu Singhal, Alyson Andreasen, Farida Gadalla, Jill Fong, Matthew C. Gomillion, Jinny Kim Hartman, Howard D. Koff, Sung Hee Rhim Lee, Tama K. Van Decar   +13 more
openalex   +2 more sources

DOSE RESPONSE RELATIONSHIP IN A MEASUREMENT ERROR MODEL

, 1988
Isao Yoshimura
openalex   +2 more sources

Dose-response relationships for edrophonium and neostigmine antagonism of atracurium and cisatracurium- induced neuromuscular block [PDF]

, 2000
Mohamed Naguib, Waleed Riad
openalex   +1 more source

Dose-response relationship between transfusion and the incidence of infection in critically ill patients: a systematic review and dose-response meta-analysis. [PDF]

J Intensive Care
Yoshihiro S, Kataoka Y, Hongo T, Tsuge T, Matsuo H.   +4 more
europepmc   +1 more source