Drug therapy: dose-response relationship of oral mesalazine in inflammatory bowel disease [PDF]
Mediators of Inflammation, 1998 Mesalazine is widely used in the treatment of inflammatory bowel disease. Little is known about the doseresponse relationship and about possible dose related side effects.
C. J. J. Mulder, S. J. Van Den Hazel
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Aspects of the Relationship between Drug Dose and Drug Effect
Dose-Response, 2009 It is generally assumed that there exists a well-defined relationship between drug dose and drug effect and that this can be expressed by a dose-response curve.
Abraham Peper
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Evidence for a curvilinear dose-response relationship between avoidance coping and drug use problems among women who experience intimate partner violence [PDF]
Anxiety, Stress and Coping, 2014 Women who experience intimate partner violence (IPV) are at heightened risk for drug use problems. While prevailing models of drug use suggest that IPV-exposed women use drugs in an effort to escape or avoid negative affect, a dearth of literature has examined the role of avoidance coping in drug use problems within this population.
Tami Sullivan, Nicole Weiss
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Risk factors for tigecycline-associated drug-induced liver injury in critically Ill patients: a 2020–2023 retrospective study from a Chinese hospital [PDF]
BMC Infectious DiseasesBackground Tigecycline is extensively used in Chinese intensive care unit (ICU) for multidrug-resistant infections, yet the profile of its associated drug-induced liver injury (DILI) requires further investigation.
Yonghui Wang +3 more
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A simple calculation of the maximum dose of the local anesthetic in pediatric dentistry with nomogram [PDF]
Vojnosanitetski Pregled, 2022 nema
Mladenović Raša
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Evaluating the relationship between Ex3 vNTR and rs3758653 polymorphisms in DRD4 genes in children with attention deficit hyperactivity disorder with respect to the dose of methylphenidate [PDF]
مجله پزشکی دانشگاه علوم پزشکی تبریز, 2022 Background. Attention deficit hyperactivity disorder (ADHD) is one of the most common psychiatric disorders starting at an early age with symptoms of attention deficit hyperactivity disorder and impulsivity.
Shahrokh Amiri +5 more
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Adverse effects of long term, continual administration of high doses of albendazole in the treatment of echinococcal disease [PDF]
Vojnosanitetski Pregled, 2008 Background/Aim. Modern treatment of cystic echinococcosis, except for surgical treatment and percutaneous drainage of cyst considers also administration of albendazole as a type of individual therapy.
Jevtić Miodrag +6 more
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drexplorer: A tool to explore dose–response relationships and drug–drug interactions [PDF]
Bioinformatics, 2015 AbstractMotivation: Nonlinear dose–response models are primary tools for estimating the potency [e.g. half-maximum inhibitory concentration (IC) known as IC50] of anti-cancer drugs. We present drexplorer software, which enables biologists to evaluate replicate reproducibility, detect outlier data points, fit different models, select the best model ...
Pan Tong +8 more
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Frontiers in Pharmacology, 2021 Traditional methods to standardize exposures in pharmacoepidemiologic studies, like defined daily-doses, may be inadequate to capture drug class effects when there are many in-class medications, formulations, and administration routes.
Kaleen N. Hayes +8 more
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Histopathologic investigations of nifedipine-induced gingival hyperplasia in Wistar rats [PDF]
Vojnosanitetski Pregled, 2005 Background. Nifedipine, a calcium channel blocker, used in the therapy of cardiovascular diseases, can induce gingival overgrowth. The aim of the study was to assess the influence of nifedipine on the deeper periodontal tissues of the experimental ...
Brkić Zlata
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