Results 181 to 190 of about 4,085,456 (259)

Clustering of Financial Time Series With Application to Index and Enhanced-index Tracking Portfolio

, 2005
C. DOSE, CINCOTTI, SILVANO
core   +1 more source

Dose modeling of superficial brachytherapy applicator geometries using multiple radioisotopes. [PDF]

Med Phys
Jegal J, Park H, Kang S, Kim JI, Choi CH, Kim S.   +5 more
europepmc   +1 more source

Intrapatient tumour heterogeneity and clonal evolution in an autopsy study of metastatic salivary gland cancer

Molecular Oncology, EarlyView.
Tumour heterogeneity and clonal evolution of metastatic salivary gland cancer were evaluated in two patients with adenoid carcinoma and one patient with myoepithelial carcinoma. Radiology‐guided autopsy enabled multi‐region sampling (total samples n = 149), followed by whole‐genome sequencing and phylogenetic reconstruction (17 tumour samples, 4–7 per ...
Gerben Lassche, Niels J. van Ruitenbeek, Charlotte Adang, Luke O'Gorman, Pui Yuen Lee, Willemijn M. Klein, Adriana C. H. van Engen‐van Grunsven, Jack A. Schalken, Sander Bervoets, Gerald W. Verhaegh, Carla M. L. van Herpen   +10 more
wiley   +1 more source

A coarse-to-fine framework combining deep learning and Monte Carlo for BNCT patient position optimization toward inverse planning. [PDF]

Med Phys
Na Y, Lee CM, Kim K, Cho H, Lee J, Ye SJ.   +5 more
europepmc   +1 more source

ADP‐ribosylation: An emerging regulator of the epigenome

Molecular Oncology, EarlyView.
ADP‐ribosylation has emerged as a dynamic epigenetic signaling mechanism that modifies histones and chromatin‐associated proteins. Through coordinated PARylation and MARylation, it integrates with other histone modifications to regulate chromatin structure, transcription factor activity, and gene expression, influencing genome function and disease ...
Cristel V. Camacho, Chenqian Liu, W. Lee Kraus   +2 more
wiley   +1 more source

A Monte Carlo based dose verification tool for an HDR Ir-192 brachytherapy source and its evaluation on extremity malignancies. [PDF]

J Appl Clin Med Phys
Li P, Kong CW, Zhang R, Zhou D, Huang C, Chiu TL, Nam PH, Yung CT, Chang TY, Yu SK, Yang B.   +10 more
europepmc   +1 more source

Castration‐resistant prostate cancer cells are addicted to the high activity of cyclin‐dependent kinase 2

Molecular Oncology, EarlyView.
We show that emergence of castration‐resistant prostate (CRPC) is associated with significant upregulation of cyclins that positively regulate cyclin‐dependent kinase 2 (CDK2) and concomitant downregulation of CDK4 cyclins. This renders CRPC cells dependent on the high activity of CDK2, and CDK2 inhibitors synergistically sensitize CRPC cells to both ...
Joyeeta Chatterjee, Alessia Marin, Shivani Yalala, Harri M. Itkonen   +3 more
wiley   +1 more source

Impact of X-ray beam quality on organ-absorbed dose in chest CT: Evaluation using spectral analysis and beam-shaping filters. [PDF]

J Appl Clin Med Phys
Ito Y, Nishihara Y, Kobayashi M, Hibino T, Asada Y.   +4 more
europepmc   +1 more source

Partial FAK suppression promotes tumor growth, an effect reversed by macrophage p110δ PI3K inactivation

Molecular Oncology, EarlyView.
Partial inhibition of focal adhesion kinase (FAK) can paradoxically promote tumor growth, rather than simply producing a weaker antitumor effect than that observed with strong FAK suppression. In breast cancer and melanoma models, targeting p110δ PI3K, particularly in macrophages, counteracted these tumor‐promoting effects, highlighting the importance ...
Lydia Xenou, Niki Tzenaki, Anna Tsapara, Maria Tzardi, Evangelia A. Papakonstanti   +4 more
wiley   +1 more source

Ein Bonapartefeind Abenteuer und Amouren, Fahrten und Fährlichkeiten des Oberstleutnant von Wahren

, 1911
Dose, Johannes 1860-1933
core