Results 51 to 60 of about 365,633 (275)

A flexible multivariate random effects proportional odds model with application to adverse effects during radiation therapy

open access: yes, 2016
Radiation therapy in patients with head and neck cancer has a toxic effect on mucosa, the soft tissue in and around the mouth. Hence mucositis is a serious common side effect and is a condition characterized by pain and inflammation of the surface of the
Augustin, Nicole   +5 more
core   +1 more source

Next‐generation proteomics improves lung cancer risk prediction

open access: yesMolecular Oncology, EarlyView.
This is one of very few studies that used prediagnostic blood samples from participants of two large population‐based cohorts. We identified, evaluated, and validated an innovative protein marker model that outperformed an established risk prediction model and criteria employed by low‐dose computed tomography in lung cancer screening trials.
Megha Bhardwaj   +4 more
wiley   +1 more source

Organ and Effective Dose Coefficients for Cranial and Caudal Irradiation Geometries: Neutrons

open access: yesEPJ Web of Conferences, 2017
With the introduction of new recommendations by ICRP Publication 103, the methodology for determining the protection quantity, effective dose, has been modified.
Veinot K.G.   +3 more
doaj   +1 more source

Comparison between planar and single-photon computed tomography images for radiation intensity quantification in iodine-131 scintigraphy

open access: yesScientific Reports, 2021
This study aimed to evaluate the feasibility of quantifying iodine-131 (131I) accumulation in scintigraphy images and compare planar and single-photon emission computed tomography (SPECT) images to estimate 131I radioactivity in patients receiving ...
Yusuke Iizuka   +4 more
doaj   +1 more source

Automatic Segmentation of Thoracic Aorta Segments in Low-Dose Chest CT

open access: yes, 2018
Morphological analysis and identification of pathologies in the aorta are important for cardiovascular diagnosis and risk assessment in patients. Manual annotation is time-consuming and cumbersome in CT scans acquired without contrast enhancement and ...
de Vos, Bob D.   +3 more
core   +1 more source

Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma

open access: yesMolecular Oncology, EarlyView.
Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken   +7 more
wiley   +1 more source

A study on the conversion coefficients of equivalent bladder dosage based on Monte Carlo simulation [PDF]

open access: yesNuclear Technology and Radiation Protection
By calculating the dose estimation coefficients for bladder phantoms with varying volumes and equivalent geometric shapes, this study offers guidance for the efficient and accurate assessment of risk organ doses 18F imaging.
Tang YanBang
doaj   +1 more source

Human biodistribution and dosimetry of [11C]-UCB-J, a PET radiotracer for imaging synaptic density

open access: yesEJNMMI Physics, 2021
Rationale [11C]-UCB-J is an emerging tool for the noninvasive measurement of synaptic vesicle density in vivo. Here, we report human biodistribution and dosimetry estimates derived from sequential whole-body PET using two versions of the OLINDA dosimetry
Christopher Cawthorne   +8 more
doaj   +1 more source

LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro

open access: yesMolecular Oncology, EarlyView.
Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix   +13 more
wiley   +1 more source

Computed Tomography Dose in Paediatric Care: Simple Dose Estimation Using Dose Length Product Conversion Coefficients

open access: yesMalaysian Journal of Medical Sciences, 2018
The use of multislice computed tomography (MSCT) is increasing worldwide; at the same time, there is a growing awareness of the future risk of cancer associated with greater exposure to radiation. Therefore, there is a need for an accessible method of effective dose estimation.
Tap, Nor Hanani Mohd   +5 more
openaire   +2 more sources

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