Results 91 to 100 of about 2,327,889 (252)

Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions

open access: yesFEBS Letters, EarlyView.
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang   +4 more
wiley   +1 more source

Dose rate dependence of electrical characteristics of lead zirconate titanate capacitors

open access: yes, 2003
The influence of gamma-radiation dose rate on the electrical properties of lead zirconate titanate capacitors was investigated. More severe degradations in dielectric constant, coercive field, remanent polarization and capacitance-voltage (C-V) curves ...
Zhang GQ,Univ Toronto,Ctr Adv Nanotechnol,170 Coll St,Toronto,ON M5S 3E4,Canada.   +9 more
core  

Dose-volume histogram (DVH).

open access: yes, 2020
(A) Dose-volume histogram for Tumor. (B) Dose-volume histogram for Matrix (absolute dose). (C) Dose-volume histogram (relative dose). (D) Table volume analysis. Tools on LGP to obtain the Paddick conformity index (CIPaddick).
Simone Coutinho Cardoso (8283012)   +5 more
core   +1 more source

The effect of duration of dependence and daily dose of tramadol in tramadol dependent patients on cognitive performance

open access: yesMiddle East Current Psychiatry, 2019
Background Tramadol dependence represents a major medical and legal hazardous phenomenon in the last decade. It is a synthetic opiate analgesic which exerts its therapeutic effect by its action on μ opioid receptors. It has a weak dependence ability. The
Hossam Eddin Khalifa Ahmad   +5 more
doaj   +1 more source

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

open access: yesFEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta   +3 more
wiley   +1 more source

Benznidazole Treatment: Time- and Dose-Dependence Varies with the Trypanosoma cruzi Strain. [PDF]

open access: yesPathogens, 2021
Fonseca KDS   +10 more
europepmc   +1 more source

Low-Dose Irradiation Differentially Impacts Macrophage Phenotype in Dependence of Fibroblast-Like Synoviocytes and Radiation Dose

open access: yesJournal of Immunology Research, 2019
Rheumatoid arthritis (RA) is a multifactorial autoimmune disease whose main hallmark is inflammation and destruction of the joints. Two cell types within the synovium that play an important role in RA are fibroblast-like synoviocytes (FLS) and ...
Lisa Deloch   +5 more
doaj   +1 more source

An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes

open access: yesFEBS Letters, EarlyView.
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg   +14 more
wiley   +1 more source

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