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Heavy atom nanoparticles, such as gold nanoparticles, are proven effective radiosensitizers in radiotherapy to enhance the dose delivery for cancer treatment.
Ngoc Han Huynh, James C. L. Chow
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Different distributions of gold nanoparticles on the tumor and calculation of dose enhancement factor by Monte Carlo simulation [PDF]
Gold nanoparticles can be used to increase the dose of the tumor due to its high atomic number as well as being free from apparent toxicity. The aim of this study is to evaluate the effect of distribution of gold nanoparticles models, as well as changes ...
Sajad Keshavarz, Dariush Sardari
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The aim of this study is the evaluation of electron dose enhancement and photon contamination production by various nanoparticles in the electron mode of a medical linac. MCNPX Monte Carlo code was used for simulation of Siemens Primus linac as well as a
Toossi Mohammad Taghi Bahreyni +4 more
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Energy Optimization And Calculation Of Dose Absorption Enhancement Factor In Photon Activation Therapy [PDF]
Introduction: Secondary radiation such as photoelectrons, Auger electrons and characteristic radiations cause a local boost in dose for a tumor when irradiated with an external X-ray beam after being loaded with elements capable of activating the tumor ...
Hassan Ranjbar +2 more
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AbstractBackgroundThe introduction of Gold NanoParticles (GNPs) in radiotherapy treatments necessitates considerations such as GNP size, location, and quantity, as well as patient geometry and beam quality. Physics considerations span length scales across many orders of magnitude (nanometer‐to‐centimeter), presenting challenges that often limit the ...
Martinov, Martin P. +2 more
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Size Effects of Gold and Iron Nanoparticles on Radiation Dose Enhancement in Brachytherapy and Teletherapy: A Monte Carlo Study [PDF]
Introduction In this study, we aimed to calculate dose enhancement factor (DEF) for gold (Au) and iron (Fe) nanoparticles (NPs) in brachytherapy and teletherapy, using Monte Carlo (MC) method.
Ahad Ollah Ezzati +2 more
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IMPACT OF NANOPARTICLE CLUSTERING ON DOSE RADIO-ENHANCEMENT
High atomic number nanoparticles (NPs) have been shown to enhance the effects of radiation in vitro and in vivo. However, NPs are often observed to cluster together, leading to inhomogeneous distribution within the tissue and within cells themselves. The effect of this clustering on the capability of NPs to enhance radiation dose has not yet been fully
Hilary, Byrne +2 more
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: The energy deposition and radiation dose from commonly used radioisotopes, 125I,103Pd, and 131Cs, used for brachytherapy of cancers is estimated using Monte Carlo (MC) simulations.
Hamda Khan +2 more
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Adaptive Visual Saliency Feature Enhancement of CBCT for Image-Guided Radiotherapy
Unlike the high imaging radiation dose of computed tomography (CT), cone-beam CT (CBCT) has smaller radiation dose and presents less harm to patients. Therefore, CBCT is often used for target delineation, dose planning, and postoperative evaluation in ...
Lisiqi Xie, Kangjian He, Dan Xu
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Background Gadolinium-based nanoparticles (GdNPs) are clinically used agents to increase the radiosensitivity of tumor cells. However, studies on the mechanisms and biological modeling of GdNP radio-enhancement are still preliminary.
Jianan Wu +5 more
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