Results 41 to 50 of about 1,766,452 (265)

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Diversity and complexity in neural organoids

FEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

The Effect of Radionuclide and Chemical Contamination on Morphological and Anatomical Parameters of Plants

Plants
This article presents the results of a study of the influence of radionuclide and chemical pollution on the morphological and anatomical parameters of Calamagróstis epigéjos plants growing in the territory of “Degelen” at the Semipalatinsk Test Site (STS)
Alyona Yankauskas, Natalya Larionova, Anton Shatrov, Anna Toporova   +3 more
doaj   +1 more source

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

FEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto, Masatomo So, Ayako Furukawa, Kenji Sugase   +3 more
wiley   +1 more source

Monitoring of radiation hygienic situation in the area of the Argun production mining and chemical association [PDF]

Саратовский научно-медицинский журнал, 2013
The Argun Production Mining and Chemical Association is a multi-activity mining company which perfprms mining of uranium ore, carries out refining of such ores in hydrometallurgical process to produce natural uranium oxide.
Shandala N.K., Titov А.V., Kiselev S.М., Seregin V.A., Isaev D.V., Semenova M.P.   +5 more
doaj  

Salmonella lipopolysaccharide‐containing supported lipid bilayers as platforms to study bacteriophage interactions

FEBS Letters, EarlyView.
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace, Alyssa Borges, Charles Arnaud, Tove Karlsson, Nina K. Bröker, Stefanie Barbirz, Marta Bally   +6 more
wiley   +1 more source

Assessment the impact of hybrid dose rates intensity modulated radiation therapy planning technique in patients with head and neck cancer

Egyptian Journal of Cancer and Biomedical Research
Background: Head and neck cancer incidence is high with radiotherapy representing integral part of treatment with different advanced techniques emerging along with different adverse events profile for each evolving technique.
ahmed adel, Omneya elemary, Hanady hegazy, Mohamed Abougylah, wahib attia   +4 more
doaj   +1 more source

Enhanced Low Dose Rate Sensitivity at Ultra-Low Dose Rates [PDF]

IEEE Transactions on Nuclear Science, 2011
We present results on the effects of ELDRS at dose rates of 10, 5, 1, and 0.5 mrad(Si)/s for a variety of commercial, radiation hardened, and ELDRS-free devices. We observed low dose rate enhancement below 10 mrad(Si)/s in several different part types. The magnitudes of the low dose rate enhancement varied substantially.
Dakai Chen, Ronald Pease, Kirby Kruckmeyer, James Forney, Anthony Phan, Martin Carts, Stephen Cox, Sam Burns, Rafi Albarian, Bruce Holcombe, Bradley Little, James Salzman, Geraldine Chaumont, Herve Duperray, Al Ouellet, Stephen Buchner, Kenneth LaBel   +16 more
openaire   +1 more source

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

FEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

ESTIMATION OF THE MODERN DOSES OF AN ARTIFICIAL EXPOSURE FOR THE INHABITANTS OF THE SETTLEMENTS LOCATED ON THE COAST OF YENISEI IN A ZONE OF SUPERVISION OF FSUE «MINING AND CHEMICAL ESTABLISHMENT»

Радиационная гигиена, 2015
The research objective consists in an estimation of modern exposure doses for the inhabitants of six settlements located on the coasts of the river Yenisei, including the doses caused by artificial radioactive contamination, connected with activity of ...
A. I. Grigorev, L. V. Pankratov, S. E. Skudarnov, Yu. S. Churikova   +3 more
doaj